| # | % | |||||
|---|---|---|---|---|---|---|
| 201 | BVF INC/IL | 6,059,625 | 50,719,000 | 3.56% | ||
| 202 | MILLENNIUM MANAGEMENT LLC | 6,604,997 | 55,284,000 | 3.88% | ||
| 203 | FRANKLIN RESOURCES INC | 8,950,982 | 74,920,000 | 5.26% | ||
| 204 | STATE STREET CORP | 9,544,525 | 79,890,000 | 5.61% | ||
| 205 | BlackRock Finance, Inc. | 12,994,700 | 108,765,000 | 7.63% | ||
| 206 | ORBIMED ADVISORS LLC | 14,182,900 | 118,711,000 | 8.33% | ||
| 207 | Redmile Group, LLC | 16,093,786 | 134,705,000 | 9.45% | ||
| 208 | FMR LLC | 18,532,336 | 155,116,000 | 10.88% | ||
| 209 | VANGUARD GROUP INC | 19,622,890 | 164,243,000 | 11.52% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
