| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 34,310,948 | 267,969,000 | 17.81% | ||
| 2 | Meditor Group Ltd | 22,070,213 | 172,368,000 | 11.45% | ||
| 3 | VANGUARD GROUP INC | 16,457,824 | 128,536,000 | 8.54% | ||
| 4 | PRICE T ROWE ASSOCIATES INC /MD/ | 15,526,930 | 121,265,000 | 8.06% | ||
| 5 | BlackRock Fund Advisors | 9,104,003 | 71,102,000 | 4.72% | ||
| 6 | Invesco Ltd. | 6,485,818 | 50,654,000 | 3.37% | ||
| 7 | STATE STREET CORP | 6,356,435 | 49,641,000 | 3.30% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 5,357,463 | 41,842,000 | 2.78% | ||
| 9 | FARALLON CAPITAL MANAGEMENT LLC | 4,915,000 | 38,386,000 | 2.55% | ||
| 10 | GOLDMAN SACHS GROUP INC | 4,227,853 | 33,019,000 | 2.19% | ||
| 11 | MILLENNIUM MANAGEMENT LLC | 4,139,212 | 32,327,000 | 2.15% | ||
| 12 | JANUS HENDERSON INVESTORS US LLC | 3,291,067 | 25,702,000 | 1.71% | ||
| 13 | GREAT POINT PARTNERS LLC | 3,200,000 | 24,992,000 | 1.66% | ||
| 14 | LORD, ABBETT & CO. LLC | 2,905,222 | 22,690,000 | 1.51% | ||
| 15 | CITADEL ADVISORS LLC | 2,604,675 | 20,342,000 | 1.35% | ||
| 16 | BAKER BROS. ADVISORS LP | 2,580,000 | 20,150,000 | 1.34% | ||
| 17 | NORTHERN TRUST CORP | 2,561,166 | 20,002,000 | 1.33% | ||
| 18 | NEA Management Company, LLC | 2,207,000 | 17,237,000 | 1.15% | ||
| 19 | SECTOR GAMMA AS | 2,059,833 | 16,087,000 | 1.07% | ||
| 20 | Point72 Asset Management, L.P. | 2,025,400 | 15,818,000 | 1.05% | ||
| 21 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,977,251 | 15,442,000 | 1.03% | ||
| 22 | CITIGROUP INC | 1,928,844 | 15,064,000 | 1.00% | ||
| 23 | GEODE CAPITAL MANAGEMENT, LLC | 1,732,779 | 13,532,000 | 0.90% | ||
| 24 | TWO SIGMA INVESTMENTS, LP | 1,605,443 | 12,539,000 | 0.83% | ||
| 25 | VOYA INVESTMENT MANAGEMENT LLC | 1,550,199 | 12,107,000 | 0.80% | ||
| 26 | Tekla Capital Management LLC | 1,405,420 | 10,976,000 | 0.73% | ||
| 27 | BANK OF AMERICA CORP /DE/ | 1,348,998 | 10,535,000 | 0.70% | ||
| 28 | NORGES BANK | 1,278,794 | 9,987,000 | 0.66% | ||
| 29 | Bank of New York Mellon Corp | 1,250,820 | 9,770,000 | 0.65% | ||
| 30 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,228,100 | 9,591,000 | 0.64% | Call | |
| 31 | WELLINGTON MANAGEMENT GROUP LLP | 1,197,671 | 9,354,000 | 0.62% | ||
| 32 | TIAA CREF INVESTMENT MANAGEMENT LLC | 1,173,937 | 9,168,000 | 0.61% | ||
| 33 | Allianz Asset Management GmbH | 1,083,330 | 8,461,000 | 0.56% | ||
| 34 | KINGDON CAPITAL MANAGEMENT, L.L.C. | 1,014,130 | 7,920,000 | 0.53% | ||
| 35 | TWO SIGMA ADVISERS, LP | 978,790 | 7,644,000 | 0.51% | ||
| 36 | BlackRock Investment Management, LLC | 880,601 | 6,877,000 | 0.46% | ||
| 37 | Rhenman & Partners Asset Management AB | 800,000 | 6,248,000 | 0.42% | ||
| 38 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 796,015 | 6,217,000 | 0.41% | ||
| 39 | OXFORD ASSET MANAGEMENT LLP | 760,959 | 5,943,000 | 0.39% | ||
| 40 | DRIEHAUS CAPITAL MANAGEMENT LLC | 630,843 | 4,927,000 | 0.33% | ||
| 41 | Informed Momentum Co LLC | 560,317 | 4,376,000 | 0.29% | ||
| 42 | DEUTSCHE BANK AG\ | 519,522 | 4,055,000 | 0.27% | ||
| 43 | Jupiter Investment Management Ltd | 510,142 | 3,984,000 | 0.26% | ||
| 44 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 477,493 | 3,729,000 | 0.25% | ||
| 45 | ALLIANCEBERNSTEIN L.P. | 410,478 | 3,206,000 | 0.21% | ||
| 46 | CREDIT SUISSE AG/ | 407,732 | 3,185,000 | 0.21% | ||
| 47 | BLAIR WILLIAM & CO/IL | 406,390 | 3,174,000 | 0.21% | ||
| 48 | MORGAN STANLEY | 397,359 | 3,103,000 | 0.21% | ||
| 49 | Asset Management One Co., Ltd. | 374,280 | 2,919,000 | 0.19% | ||
| 50 | GUGGENHEIM CAPITAL LLC | 370,240 | 2,892,000 | 0.19% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
