| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 4,251,478 | 223,160,000 | 16.18% | ||
| 2 | WELLINGTON MANAGEMENT GROUP LLP | 2,496,986 | 131,067,000 | 9.50% | ||
| 3 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 2,125,100 | 111,546,000 | 8.09% | ||
| 4 | VANGUARD GROUP INC | 1,722,827 | 90,432,000 | 6.56% | ||
| 5 | ACADIAN ASSET MANAGEMENT LLC | 1,111,332 | 58,332,000 | 4.23% | ||
| 6 | BlackRock Fund Advisors | 1,080,243 | 56,702,000 | 4.11% | ||
| 7 | STATE STREET CORP | 1,061,061 | 55,691,000 | 4.04% | ||
| 8 | EVENTIDE ASSET MANAGEMENT, LLC | 1,015,200 | 53,288,000 | 3.86% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 752,276 | 39,487,000 | 2.86% | ||
| 10 | DIMENSIONAL FUND ADVISORS LP | 747,861 | 39,255,000 | 2.85% | ||
| 11 | GOLDMAN SACHS GROUP INC | 654,352 | 34,347,000 | 2.49% | ||
| 12 | VICTORY CAPITAL MANAGEMENT INC | 588,733 | 30,903,000 | 2.24% | ||
| 13 | CANADA PENSION PLAN INVESTMENT BOARD | 474,800 | 24,922,000 | 1.81% | ||
| 14 | OppenheimerFunds, Inc. | 393,850 | 20,673,000 | 1.50% | ||
| 15 | NORTHERN TRUST CORP | 337,743 | 17,727,000 | 1.28% | ||
| 16 | BOGLE INVESTMENT MANAGEMENT L P /DE/ | 333,449 | 17,502,000 | 1.27% | ||
| 17 | DEERFIELD MANAGEMENT COMPANY, L.P. | 311,000 | 16,324,000 | 1.18% | ||
| 18 | EcoR1 Capital, LLC | 286,612 | 15,044,000 | 1.09% | ||
| 19 | GEODE CAPITAL MANAGEMENT, LLC | 243,266 | 12,768,000 | 0.93% | ||
| 20 | TEACHERS ADVISORS, LLC | 236,870 | 12,433,000 | 0.90% | ||
| 21 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 217,878 | 11,437,000 | 0.83% | ||
| 22 | EMERALD ACQUISITION LTD. | 204,006 | 10,708,000 | 0.78% | ||
| 23 | TIAA CREF INVESTMENT MANAGEMENT LLC | 183,282 | 9,620,000 | 0.70% | ||
| 24 | AQR CAPITAL MANAGEMENT LLC | 182,908 | 9,601,000 | 0.70% | ||
| 25 | Invesco Ltd. | 174,488 | 9,158,000 | 0.66% | ||
| 26 | PERCEPTIVE ADVISORS LLC | 166,509 | 8,740,000 | 0.63% | ||
| 27 | Rock Springs Capital Management LP | 166,250 | 8,726,000 | 0.63% | ||
| 28 | WELLS FARGO & COMPANY/MN | 157,545 | 8,269,000 | 0.60% | ||
| 29 | PICTET ASSET MANAGEMENT LTD | 156,719 | 8,226,000 | 0.60% | ||
| 30 | CAPITAL FUND MANAGEMENT S.A. | 153,680 | 8,067,000 | 0.58% | ||
| 31 | Bank of New York Mellon Corp | 144,458 | 7,582,000 | 0.55% | ||
| 32 | JPMORGAN CHASE & CO | 129,775 | 6,812,000 | 0.49% | ||
| 33 | HUSSMAN STRATEGIC ADVISORS, INC. | 125,000 | 6,561,000 | 0.48% | ||
| 34 | HAYS ADVISORY LLC | 123,148 | 6,464,000 | 0.47% | ||
| 35 | Matarin Capital Management, LLC | 117,303 | 6,157,235 | 0.45% | ||
| 36 | DRIEHAUS CAPITAL MANAGEMENT LLC | 115,563 | 6,066,000 | 0.44% | ||
| 37 | LORD, ABBETT & CO. LLC | 113,062 | 5,934,000 | 0.43% | ||
| 38 | BlackRock Investment Management, LLC | 109,459 | 5,746,000 | 0.42% | ||
| 39 | ALLIANCEBERNSTEIN L.P. | 107,750 | 5,656,000 | 0.41% | ||
| 40 | SKANDINAVISKA ENSKILDA BANKEN AB (PUBL) | 99,100 | 5,202,000 | 0.38% | ||
| 41 | DEUTSCHE BANK AG\ | 98,765 | 5,181,000 | 0.38% | ||
| 42 | Zurcher Kantonalbank (Zurich Cantonalbank) | 97,015 | 5,092,000 | 0.37% | ||
| 43 | D. E. Shaw & Co., Inc. | 87,915 | 4,615,000 | 0.33% | ||
| 44 | AWM Investment Company, Inc. | 80,000 | 4,199,000 | 0.30% | ||
| 45 | CREDIT SUISSE AG/ | 76,696 | 4,026,000 | 0.29% | ||
| 46 | Spark Investment Management LLC | 73,400 | 3,852,000 | 0.28% | ||
| 47 | GSA CAPITAL PARTNERS LLP | 71,000 | 3,727,000 | 0.27% | ||
| 48 | Vident Investment Advisory, LLC | 65,550 | 3,441,000 | 0.25% | ||
| 49 | MACKENZIE FINANCIAL CORP | 64,873 | 3,405,000 | 0.25% | ||
| 50 | TRILLIUM ASSET MANAGEMENT, LLC | 63,864 | 3,352,000 | 0.24% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
