| # | % | |||||
|---|---|---|---|---|---|---|
| 101 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 283,300 | 5,394,000 | 0.83% | Call | |
| 102 | Informed Momentum Co LLC | 304,022 | 5,789,000 | 0.89% | ||
| 103 | OXFORD ASSET MANAGEMENT LLP | 312,397 | 5,948,000 | 0.92% | ||
| 104 | Palo Alto Investors LP | 316,699 | 6,030,000 | 0.93% | ||
| 105 | PERCEPTIVE ADVISORS LLC | 340,000 | 6,474,000 | 1.00% | ||
| 106 | Invesco Ltd. | 380,280 | 7,241,000 | 1.12% | ||
| 107 | MARSHALL WACE, LLP | 415,299 | 7,907,000 | 1.22% | ||
| 108 | NORTHERN TRUST CORP | 473,294 | 9,012,000 | 1.39% | ||
| 109 | MILLENNIUM MANAGEMENT LLC | 485,600 | 9,246,000 | 1.43% | Call | |
| 110 | BAKER BROS. ADVISORS LP | 554,050 | 10,549,000 | 1.63% | ||
| 111 | GOLDMAN SACHS GROUP INC | 584,400 | 11,127,000 | 1.72% | Put | |
| 112 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 590,200 | 11,238,000 | 1.74% | Put | |
| 113 | BARCLAYS PLC | 605,000 | 11,495,000 | 1.77% | Call | |
| 114 | Tourbillon Capital Partners, L.P. | 700,000 | 13,328,000 | 2.06% | ||
| 115 | GOLDMAN SACHS GROUP INC | 781,600 | 14,882,000 | 2.30% | Call | |
| 116 | AMERIPRISE FINANCIAL INC | 934,020 | 17,781,000 | 2.75% | ||
| 117 | JPMORGAN CHASE & CO | 935,801 | 17,818,000 | 2.75% | ||
| 118 | VANGUARD GROUP INC | 939,654 | 17,892,000 | 2.76% | ||
| 119 | BlackRock Fund Advisors | 970,670 | 18,482,000 | 2.85% | ||
| 120 | SECTORAL ASSET MANAGEMENT INC | 1,172,121 | 22,317,000 | 3.45% | ||
| 121 | BlackRock Institutional Trust Company, N.A. | 1,401,192 | 26,679,000 | 4.12% | ||
| 122 | FRANKLIN RESOURCES INC | 1,452,200 | 27,650,000 | 4.27% | ||
| 123 | STATE STREET CORP | 1,461,978 | 27,830,000 | 4.30% | ||
| 124 | MILLENNIUM MANAGEMENT LLC | 1,644,674 | 31,315,000 | 4.84% | ||
| 125 | DEERFIELD MANAGEMENT COMPANY, L.P. | 2,016,147 | 38,387,000 | 5.93% | ||
| 126 | WELLS FARGO & COMPANY/MN | 2,130,011 | 40,555,000 | 6.26% | ||
| 127 | FMR LLC | 5,889,436 | 112,135,000 | 17.31% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
