| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 5,359,831 | 47,810,000 | 25.24% | ||
| 2 | FRANKLIN RESOURCES INC | 4,284,188 | 38,215,000 | 20.17% | ||
| 3 | Palo Alto Investors LP | 3,098,145 | 27,635,000 | 14.59% | ||
| 4 | MILLENNIUM MANAGEMENT LLC | 1,306,393 | 11,653,000 | 6.15% | ||
| 5 | WELLINGTON MANAGEMENT GROUP LLP | 1,269,485 | 11,323,000 | 5.98% | ||
| 6 | BlackRock Fund Advisors | 1,057,872 | 9,436,000 | 4.98% | ||
| 7 | VANGUARD GROUP INC | 688,730 | 6,144,000 | 3.24% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 514,428 | 4,589,000 | 2.42% | ||
| 9 | Tekla Capital Management LLC | 500,324 | 4,463,000 | 2.36% | ||
| 10 | STATE STREET CORP | 360,950 | 3,220,000 | 1.70% | ||
| 11 | JPMORGAN CHASE & CO | 280,206 | 2,500,000 | 1.32% | ||
| 12 | NORTHERN TRUST CORP | 248,139 | 2,214,000 | 1.17% | ||
| 13 | BAKER BROS. ADVISORS LP | 216,990 | 1,936,000 | 1.02% | ||
| 14 | Candriam S.C.A. | 187,000 | 1,659,000 | 0.88% | ||
| 15 | GEODE CAPITAL MANAGEMENT, LLC | 138,717 | 1,237,000 | 0.65% | ||
| 16 | DEUTSCHE BANK AG\ | 102,444 | 913,000 | 0.48% | ||
| 17 | Bank of New York Mellon Corp | 97,385 | 869,000 | 0.46% | ||
| 18 | STONERIDGE INVESTMENT PARTNERS LLC | 94,141 | 840,000 | 0.44% | ||
| 19 | MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | 87,466 | 780,000 | 0.41% | ||
| 20 | GUGGENHEIM CAPITAL LLC | 85,768 | 765,000 | 0.40% | ||
| 21 | BlackRock Investment Management, LLC | 81,703 | 729,000 | 0.38% | ||
| 22 | NEW YORK STATE COMMON RETIREMENT FUND | 81,226 | 725,000 | 0.38% | ||
| 23 | TIAA CREF INVESTMENT MANAGEMENT LLC | 72,892 | 650,000 | 0.34% | ||
| 24 | A.R.T. Advisors, LLC | 67,170 | 599,000 | 0.32% | ||
| 25 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 59,616 | 532,000 | 0.28% | ||
| 26 | BANK OF AMERICA CORP /DE/ | 57,676 | 514,000 | 0.27% | ||
| 27 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 52,700 | 470,000 | 0.25% | Call | |
| 28 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 49,591 | 442,000 | 0.23% | ||
| 29 | Opus Point Partners Management, LLC | 49,500 | 442,000 | 0.23% | ||
| 30 | ROYAL BANK OF CANADA | 43,600 | 388,000 | 0.20% | ||
| 31 | Numeric Investors LLC | 42,819 | 382,000 | 0.20% | ||
| 32 | TCW GROUP INC | 41,652 | 372,000 | 0.20% | ||
| 33 | ALPS ADVISORS INC | 40,184 | 358,000 | 0.19% | ||
| 34 | TEACHERS ADVISORS, LLC | 36,532 | 326,000 | 0.17% | ||
| 35 | Swiss National Bank | 34,350 | 296,000 | 0.16% | ||
| 36 | ProShare Advisors LLC | 29,279 | 261,000 | 0.14% | ||
| 37 | ALLIANCEBERNSTEIN L.P. | 28,130 | 251,000 | 0.13% | ||
| 38 | Connor, Clark & Lunn Investment Management Ltd. | 27,300 | 244,000 | 0.13% | ||
| 39 | CAXTON CORP | 24,829 | 221,000 | 0.12% | ||
| 40 | RHUMBLINE ADVISERS | 22,341 | 199,000 | 0.11% | ||
| 41 | MORGAN STANLEY | 21,494 | 192,000 | 0.10% | ||
| 42 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 19,400 | 173,000 | 0.09% | Put | |
| 43 | VIRTUS ETF ADVISERS LLC | 17,923 | 160,000 | 0.08% | ||
| 44 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 17,919 | 160,000 | 0.08% | ||
| 45 | CITIGROUP INC | 17,588 | 157,000 | 0.08% | ||
| 46 | Nationwide Fund Advisors | 15,372 | 137,000 | 0.07% | ||
| 47 | DekaBank Deutsche Girozentrale | 15,500 | 134,000 | 0.07% | ||
| 48 | WELLS FARGO & COMPANY/MN | 15,172 | 134,000 | 0.07% | ||
| 49 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 15,337 | 133,000 | 0.07% | ||
| 50 | AMERICAN INTERNATIONAL GROUP, INC. | 14,026 | 125,000 | 0.07% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
