| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | MPM ASSET MANAGEMENT LLC | 5,831,253 | 122,456,000 | 39.93% | ||
| 2 | BB BIOTECH AG | 2,745,040 | 57,646,000 | 18.80% | ||
| 3 | Bain Capital Public Equity Management, LLC | 1,824,524 | 38,315,000 | 12.50% | ||
| 4 | WELLCOME TRUST LTD (THE) as trustee of the WELLCOME TRUST | 1,726,841 | 36,263,000 | 11.83% | ||
| 5 | FARALLON CAPITAL MANAGEMENT LLC | 949,500 | 19,940,000 | 6.50% | ||
| 6 | CITADEL ADVISORS LLC | 419,845 | 8,817,000 | 2.88% | ||
| 7 | JPMORGAN CHASE & CO | 201,600 | 4,234,000 | 1.38% | ||
| 8 | BlackRock Fund Advisors | 172,731 | 3,627,000 | 1.18% | ||
| 9 | SPHERA FUNDS MANAGEMENT LTD. | 150,000 | 3,150,000 | 1.03% | ||
| 10 | FMR LLC | 118,673 | 2,492,000 | 0.81% | ||
| 11 | STATE STREET CORP | 57,900 | 1,216,000 | 0.40% | ||
| 12 | BlackRock Institutional Trust Company, N.A. | 56,538 | 1,187,000 | 0.39% | ||
| 13 | VANGUARD GROUP INC | 49,472 | 1,039,000 | 0.34% | ||
| 14 | Numeric Investors LLC | 37,785 | 793,000 | 0.26% | ||
| 15 | GOLDMAN SACHS GROUP INC | 36,972 | 776,000 | 0.25% | ||
| 16 | GEODE CAPITAL MANAGEMENT, LLC | 34,678 | 728,000 | 0.24% | ||
| 17 | Spark Investment Management LLC | 27,900 | 578,000 | 0.19% | ||
| 18 | A.R.T. Advisors, LLC | 19,876 | 417,000 | 0.14% | ||
| 19 | BlackRock Investment Management, LLC | 19,706 | 414,000 | 0.14% | ||
| 20 | TIAA CREF INVESTMENT MANAGEMENT LLC | 18,001 | 378,000 | 0.12% | ||
| 21 | Bank of New York Mellon Corp | 16,654 | 349,000 | 0.11% | ||
| 22 | Rathbones Group PLC | 14,590 | 306,000 | 0.10% | ||
| 23 | NORTHERN TRUST CORP | 14,081 | 296,000 | 0.10% | ||
| 24 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 12,900 | 271,000 | 0.09% | ||
| 25 | JANE STREET GROUP, LLC | 10,317 | 217,000 | 0.07% | ||
| 26 | MORGAN STANLEY | 9,319 | 195,000 | 0.06% | ||
| 27 | BANK OF AMERICA CORP /DE/ | 8,600 | 181,000 | 0.06% | ||
| 28 | TEACHERS ADVISORS, LLC | 6,537 | 137,000 | 0.04% | ||
| 29 | BLACKROCK ADVISORS LLC | 2,732 | 57,000 | 0.02% | ||
| 30 | WELLS FARGO & COMPANY/MN | 2,500 | 53,000 | 0.02% | ||
| 31 | STRS OHIO | 2,400 | 50,000 | 0.02% | ||
| 32 | Nationwide Fund Advisors | 2,056 | 43,000 | 0.01% | ||
| 33 | UBS AG | 495 | 10,000 | 0.00% | ||
| 34 | CITIGROUP INC | 245 | 5,000 | 0.00% | ||
| 35 | BlackRock Finance, Inc. | 201 | 4,000 | 0.00% | ||
| 36 | DEUTSCHE BANK AG\ | 2 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
