| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 5,575,494 | 377,907,000 | 12.14% | ||
| 2 | BAILLIE GIFFORD & CO | 4,998,833 | 338,821,000 | 10.88% | ||
| 3 | Capital Research Global Investors | 3,992,809 | 270,633,000 | 8.69% | ||
| 4 | PRICE T ROWE ASSOCIATES INC /MD/ | 3,365,797 | 228,134,000 | 7.33% | ||
| 5 | VANGUARD GROUP INC | 2,735,732 | 185,428,000 | 5.96% | ||
| 6 | WELLINGTON MANAGEMENT GROUP LLP | 1,963,639 | 133,096,000 | 4.27% | ||
| 7 | STATE STREET CORP | 1,659,517 | 112,485,000 | 3.61% | ||
| 8 | BlackRock Fund Advisors | 1,475,395 | 100,002,000 | 3.21% | ||
| 9 | ORBIMED ADVISORS LLC | 1,185,800 | 80,374,000 | 2.58% | ||
| 10 | FRANKLIN RESOURCES INC | 1,161,832 | 78,749,000 | 2.53% | ||
| 11 | BlackRock Institutional Trust Company, N.A. | 935,722 | 63,423,000 | 2.04% | ||
| 12 | JENNISON ASSOCIATES LLC | 867,437 | 58,795,000 | 1.89% | ||
| 13 | OppenheimerFunds, Inc. | 788,099 | 53,418,000 | 1.72% | ||
| 14 | Capital World Investors | 752,000 | 50,971,000 | 1.64% | ||
| 15 | VICTORY CAPITAL MANAGEMENT INC | 654,930 | 44,391,000 | 1.43% | ||
| 16 | MILLENNIUM MANAGEMENT LLC | 653,144 | 44,270,000 | 1.42% | ||
| 17 | BALYASNY ASSET MANAGEMENT L.P. | 548,684 | 37,190,000 | 1.19% | ||
| 18 | EVENTIDE ASSET MANAGEMENT, LLC | 539,500 | 36,567,000 | 1.17% | ||
| 19 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 467,500 | 31,687,000 | 1.02% | Put | |
| 20 | WELLS FARGO & COMPANY/MN | 425,639 | 28,850,000 | 0.93% | ||
| 21 | NORTHERN TRUST CORP | 411,712 | 27,906,000 | 0.90% | ||
| 22 | NORGES BANK | 422,618 | 27,359,000 | 0.88% | ||
| 23 | ArrowMark Colorado Holdings LLC | 396,897 | 26,902,000 | 0.86% | ||
| 24 | Artal Group S.A. | 385,000 | 26,095,000 | 0.84% | ||
| 25 | DEUTSCHE BANK AG\ | 382,110 | 25,896,000 | 0.83% | ||
| 26 | EMERALD ADVISERS, LLC | 373,554 | 25,319,000 | 0.81% | ||
| 27 | AMERIPRISE FINANCIAL INC | 363,852 | 24,664,000 | 0.79% | ||
| 28 | EMERALD MUTUAL FUND ADVISERS TRUST | 323,863 | 21,951,000 | 0.71% | ||
| 29 | BAKER BROS. ADVISORS LP | 293,943 | 19,923,000 | 0.64% | ||
| 30 | Passport Capital, LLC | 289,068 | 19,593,000 | 0.63% | ||
| 31 | GEODE CAPITAL MANAGEMENT, LLC | 278,959 | 18,907,000 | 0.61% | ||
| 32 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 241,394 | 16,361,000 | 0.53% | ||
| 33 | Invesco Ltd. | 230,338 | 15,612,000 | 0.50% | ||
| 34 | DEERFIELD MANAGEMENT COMPANY, L.P. | 224,000 | 15,183,000 | 0.49% | ||
| 35 | Bank of New York Mellon Corp | 194,978 | 13,215,000 | 0.42% | ||
| 36 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 194,100 | 13,156,000 | 0.42% | Call | |
| 37 | GOLDMAN SACHS GROUP INC | 184,355 | 12,496,000 | 0.40% | ||
| 38 | COLUMBUS CIRCLE INVESTORS | 172,034 | 11,660,000 | 0.37% | ||
| 39 | AXA S.A. | 163,651 | 11,092,000 | 0.36% | ||
| 40 | NEW YORK STATE COMMON RETIREMENT FUND | 155,055 | 10,510,000 | 0.34% | ||
| 41 | Mitsubishi UFJ Trust & Banking Corp | 154,660 | 10,483,000 | 0.34% | ||
| 42 | BlackRock Investment Management, LLC | 154,127 | 10,447,000 | 0.34% | ||
| 43 | Polar Capital LLP | 152,678 | 10,349,000 | 0.33% | ||
| 44 | TEACHERS ADVISORS, LLC | 151,646 | 10,279,000 | 0.33% | ||
| 45 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 140,491 | 9,523,000 | 0.31% | ||
| 46 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 134,763 | 9,134,000 | 0.29% | ||
| 47 | BLACKROCK ADVISORS LLC | 128,615 | 8,718,000 | 0.28% | ||
| 48 | TIAA CREF INVESTMENT MANAGEMENT LLC | 127,462 | 8,639,000 | 0.28% | ||
| 49 | BANK OF AMERICA CORP /DE/ | 124,334 | 8,428,000 | 0.27% | ||
| 50 | Hood River Capital Management LLC | 119,080 | 8,071,000 | 0.26% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
