| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 6,088,971 | 375,689,000 | 12.71% | ||
| 2 | BAILLIE GIFFORD & CO | 5,164,467 | 318,647,000 | 10.78% | ||
| 3 | Capital Research Global Investors | 4,713,042 | 290,795,000 | 9.84% | ||
| 4 | PRICE T ROWE ASSOCIATES INC /MD/ | 3,288,161 | 202,880,000 | 6.86% | ||
| 5 | VANGUARD GROUP INC | 3,073,953 | 189,663,000 | 6.42% | ||
| 6 | WELLINGTON MANAGEMENT GROUP LLP | 3,049,519 | 188,156,000 | 6.37% | ||
| 7 | BlackRock Fund Advisors | 1,813,191 | 111,874,000 | 3.78% | ||
| 8 | STATE STREET CORP | 1,552,804 | 95,814,000 | 3.24% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 1,005,508 | 62,040,000 | 2.10% | ||
| 10 | VICTORY CAPITAL MANAGEMENT INC | 983,609 | 60,688,000 | 2.05% | ||
| 11 | OppenheimerFunds, Inc. | 971,471 | 59,940,000 | 2.03% | ||
| 12 | FRANKLIN RESOURCES INC | 925,300 | 57,091,000 | 1.93% | ||
| 13 | JENNISON ASSOCIATES LLC | 870,511 | 53,711,000 | 1.82% | ||
| 14 | BALYASNY ASSET MANAGEMENT L.P. | 706,035 | 43,562,000 | 1.47% | ||
| 15 | Capital World Investors | 625,000 | 38,563,000 | 1.30% | ||
| 16 | EVENTIDE ASSET MANAGEMENT, LLC | 587,677 | 36,260,000 | 1.23% | ||
| 17 | WELLS FARGO & COMPANY/MN | 468,012 | 28,878,000 | 0.98% | ||
| 18 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 461,200 | 28,456,000 | 0.96% | Put | |
| 19 | NORTHERN TRUST CORP | 455,548 | 28,107,000 | 0.95% | ||
| 20 | ArrowMark Colorado Holdings LLC | 453,354 | 27,972,000 | 0.95% | ||
| 21 | Artal Group S.A. | 422,536 | 26,070,000 | 0.88% | ||
| 22 | NORGES BANK | 371,793 | 22,940,000 | 0.78% | ||
| 23 | BAKER BROS. ADVISORS LP | 351,441 | 21,684,000 | 0.73% | ||
| 24 | AMERIPRISE FINANCIAL INC | 341,626 | 21,079,000 | 0.71% | ||
| 25 | GEODE CAPITAL MANAGEMENT, LLC | 326,610 | 20,151,000 | 0.68% | ||
| 26 | DEUTSCHE BANK AG\ | 310,756 | 19,171,000 | 0.65% | ||
| 27 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 306,300 | 18,899,000 | 0.64% | Call | |
| 28 | DEERFIELD MANAGEMENT COMPANY, L.P. | 302,027 | 18,635,000 | 0.63% | ||
| 29 | Alyeska Investment Group, L.P. | 296,107 | 18,270,000 | 0.62% | ||
| 30 | ORBIMED ADVISORS LLC | 283,800 | 17,510,000 | 0.59% | ||
| 31 | GOLDMAN SACHS GROUP INC | 265,208 | 16,364,000 | 0.55% | ||
| 32 | Invesco Ltd. | 254,748 | 15,718,000 | 0.53% | ||
| 33 | COLUMBUS CIRCLE INVESTORS | 248,980 | 15,362,000 | 0.52% | ||
| 34 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 231,292 | 14,272,000 | 0.48% | ||
| 35 | Bank of New York Mellon Corp | 206,652 | 12,751,000 | 0.43% | ||
| 36 | FRONTIER CAPITAL MANAGEMENT CO LLC | 201,454 | 12,430,000 | 0.42% | ||
| 37 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 170,676 | 10,531,000 | 0.36% | ||
| 38 | EMERALD ADVISERS, LLC | 164,940 | 10,177,000 | 0.34% | ||
| 39 | JPMORGAN CHASE & CO | 158,258 | 9,765,000 | 0.33% | ||
| 40 | BlackRock Investment Management, LLC | 157,838 | 9,739,000 | 0.33% | ||
| 41 | Mitsubishi UFJ Trust & Banking Corp | 157,200 | 9,699,000 | 0.33% | ||
| 42 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 154,599 | 9,539,000 | 0.32% | ||
| 43 | TIAA CREF INVESTMENT MANAGEMENT LLC | 148,033 | 9,134,000 | 0.31% | ||
| 44 | MORGAN STANLEY | 146,684 | 9,051,000 | 0.31% | ||
| 45 | PICTET ASSET MANAGEMENT LTD | 144,916 | 8,941,000 | 0.30% | ||
| 46 | NEW YORK STATE COMMON RETIREMENT FUND | 142,608 | 8,799,000 | 0.30% | ||
| 47 | Candriam S.C.A. | 137,000 | 8,452,000 | 0.29% | ||
| 48 | BANK OF AMERICA CORP /DE/ | 134,822 | 8,319,000 | 0.28% | ||
| 49 | AXA S.A. | 131,134 | 8,091,000 | 0.27% | ||
| 50 | RTW INVESTMENTS, LP | 122,576 | 7,563,000 | 0.26% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
