| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BROWN CAPITAL MANAGEMENT LLC | 8,783,162 | 63,590,000 | 9.19% | ||
| 2 | ArrowMark Colorado Holdings LLC | 7,119,669 | 51,546,000 | 7.45% | ||
| 3 | VANGUARD GROUP INC | 6,285,069 | 45,505,000 | 6.58% | ||
| 4 | COLUMBIA WANGER ASSET MANAGEMENT LLC | 6,026,829 | 43,634,000 | 6.31% | ||
| 5 | Camber Capital Management LP | 6,000,000 | 43,440,000 | 6.28% | ||
| 6 | BlackRock Finance, Inc. | 5,019,220 | 36,338,000 | 5.25% | ||
| 7 | TimesSquare Capital Management, LLC | 3,814,670 | 27,618,000 | 3.99% | ||
| 8 | Clearbridge Investments, LLC | 3,239,894 | 23,457,000 | 3.39% | ||
| 9 | Redmile Group, LLC | 2,717,394 | 19,674,000 | 2.84% | ||
| 10 | NEA Management Company, LLC | 2,490,204 | 18,029,000 | 2.61% | ||
| 11 | WELLINGTON MANAGEMENT GROUP LLP | 2,477,102 | 17,935,000 | 2.59% | ||
| 12 | Elk Creek Partners, LLC | 2,372,991 | 17,180,000 | 2.48% | ||
| 13 | MACKENZIE FINANCIAL CORP | 2,144,131 | 15,524,000 | 2.24% | ||
| 14 | PFM Health Sciences, LP | 2,043,786 | 14,797,000 | 2.14% | ||
| 15 | Essex Woodlands Management, Inc. | 1,257,468 | 14,484,000 | 2.09% | ||
| 16 | STATE STREET CORP | 1,749,732 | 12,667,000 | 1.83% | ||
| 17 | Broadfin Capital, LLC | 1,669,020 | 12,084,000 | 1.75% | ||
| 18 | Rhenman & Partners Asset Management AB | 1,600,000 | 11,584,000 | 1.67% | ||
| 19 | BNP Paribas Asset Management Holding S.A. | 1,528,342 | 11,065,000 | 1.60% | ||
| 20 | NEW YORK STATE COMMON RETIREMENT FUND | 1,339,275 | 9,696,000 | 1.40% | ||
| 21 | Ghost Tree Capital, LLC | 1,300,000 | 9,412,000 | 1.36% | ||
| 22 | PALISADE CAPITAL MANAGEMENT, LP | 1,201,149 | 8,696,000 | 1.26% | ||
| 23 | MPM ASSET MANAGEMENT LLC | 1,121,447 | 8,119,000 | 1.17% | ||
| 24 | NORTHERN TRUST CORP | 1,052,188 | 7,617,000 | 1.10% | ||
| 25 | D. E. Shaw & Co., Inc. | 985,150 | 7,132,000 | 1.03% | ||
| 26 | AXA S.A. | 962,787 | 6,971,000 | 1.01% | ||
| 27 | FIL Ltd | 882,214 | 6,387,000 | 0.92% | ||
| 28 | PRICE T ROWE ASSOCIATES INC /MD/ | 877,626 | 6,354,000 | 0.92% | ||
| 29 | PICTET ASSET MANAGEMENT LTD | 876,208 | 6,344,000 | 0.92% | ||
| 30 | Bank of New York Mellon Corp | 839,948 | 6,081,000 | 0.88% | ||
| 31 | ALTRINSIC GLOBAL ADVISORS LLC | 790,000 | 5,720,000 | 0.83% | ||
| 32 | STEPHENS INC /AR/ | 764,688 | 5,536,000 | 0.80% | ||
| 33 | Lombard Odier Asset Management (USA) Corp | 750,000 | 5,430,000 | 0.79% | ||
| 34 | DEUTSCHE BANK AG\ | 653,002 | 4,726,000 | 0.68% | ||
| 35 | GEODE CAPITAL MANAGEMENT, LLC | 648,288 | 4,693,000 | 0.68% | ||
| 36 | KENNEDY CAPITAL MANAGEMENT LLC | 639,211 | 4,628,000 | 0.67% | ||
| 37 | AMUNDI ASSET MANAGEMENT US, INC. | 630,314 | 4,563,000 | 0.66% | ||
| 38 | Point72 Asset Management, L.P. | 622,400 | 4,506,000 | 0.65% | ||
| 39 | C WorldWide Group Holding A/S | 524,556 | 3,798,000 | 0.55% | ||
| 40 | RENAISSANCE TECHNOLOGIES LLC | 503,891 | 3,648,000 | 0.53% | ||
| 41 | CANADA LIFE ASSURANCE Co | 448,025 | 3,249,000 | 0.47% | ||
| 42 | NORGES BANK | 421,356 | 3,051,000 | 0.44% | ||
| 43 | STATE OF WISCONSIN INVESTMENT BOARD | 400,000 | 2,896,000 | 0.42% | ||
| 44 | CITADEL ADVISORS LLC | 348,460 | 2,523,000 | 0.36% | ||
| 45 | Endurant Capital Management LP | 335,007 | 2,425,000 | 0.35% | ||
| 46 | FMR LLC | 300,000 | 2,172,000 | 0.31% | ||
| 47 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 290,880 | 2,106,000 | 0.30% | ||
| 48 | GOLDMAN SACHS GROUP INC | 285,295 | 2,066,000 | 0.30% | ||
| 49 | BANK OF AMERICA CORP /DE/ | 265,523 | 1,922,000 | 0.28% | ||
| 50 | Nationwide Fund Advisors | 258,787 | 1,874,000 | 0.27% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
