| # | % | |||||
|---|---|---|---|---|---|---|
| 101 | NEW YORK STATE COMMON RETIREMENT FUND | 1,220,399 | 5,931,000 | 1.37% | ||
| 102 | PALISADE CAPITAL MANAGEMENT, LP | 1,231,437 | 5,985,000 | 1.38% | ||
| 103 | BNP Paribas Asset Management Holding S.A. | 1,550,539 | 7,536,000 | 1.74% | ||
| 104 | Rhenman & Partners Asset Management AB | 1,575,000 | 7,655,000 | 1.77% | ||
| 105 | STATE STREET CORP | 1,951,432 | 9,483,000 | 2.19% | ||
| 106 | Elk Creek Partners, LLC | 2,087,238 | 10,144,000 | 2.35% | ||
| 107 | MACKENZIE FINANCIAL CORP | 2,123,931 | 10,322,000 | 2.39% | ||
| 108 | Essex Woodlands Management, Inc. | 1,257,468 | 11,699,000 | 2.71% | ||
| 109 | NEA Management Company, LLC | 2,490,204 | 12,102,000 | 2.80% | ||
| 110 | BlackRock Finance, Inc. | 4,983,675 | 24,222,000 | 5.60% | ||
| 111 | COLUMBIA WANGER ASSET MANAGEMENT LLC | 5,244,360 | 25,488,000 | 5.89% | ||
| 112 | PFM Health Sciences, LP | 5,599,466 | 27,213,000 | 6.29% | ||
| 113 | Redmile Group, LLC | 6,368,299 | 30,950,000 | 7.16% | ||
| 114 | VANGUARD GROUP INC | 6,638,302 | 32,262,000 | 7.46% | ||
| 115 | Camber Capital Management LP | 7,500,000 | 36,450,000 | 8.43% | ||
| 116 | ArrowMark Colorado Holdings LLC | 7,639,140 | 37,126,000 | 8.59% | ||
| 117 | BROWN CAPITAL MANAGEMENT LLC | 8,783,162 | 42,686,000 | 9.87% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
