| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 1,567,709 | 13,012,000 | 16.92% | ||
| 2 | MILLENNIUM MANAGEMENT LLC | 1,155,526 | 9,591,000 | 12.47% | ||
| 3 | JPMORGAN CHASE & CO | 926,959 | 7,694,000 | 10.00% | ||
| 4 | Lombard Odier Asset Management (USA) Corp | 900,000 | 7,470,000 | 9.71% | ||
| 5 | Visium Asset Management, LP | 833,000 | 6,916,000 | 8.99% | ||
| 6 | Broadfin Capital, LLC | 641,700 | 5,326,000 | 6.93% | ||
| 7 | Redmile Group, LLC | 600,000 | 4,980,000 | 6.48% | ||
| 8 | BAKER BROS. ADVISORS LP | 571,000 | 4,739,000 | 6.16% | ||
| 9 | Foresite Capital Management I, LLC | 500,000 | 4,150,000 | 5.40% | ||
| 10 | SABBY MANAGEMENT, LLC | 341,810 | 2,837,000 | 3.69% | ||
| 11 | Artal Group S.A. | 300,000 | 2,490,000 | 3.24% | ||
| 12 | SPHERA FUNDS MANAGEMENT LTD. | 205,000 | 1,702,000 | 2.21% | ||
| 13 | Alyeska Investment Group, L.P. | 168,578 | 1,399,000 | 1.82% | ||
| 14 | Del Mar Asset Management, LP | 166,666 | 1,383,000 | 1.80% | ||
| 15 | BALYASNY ASSET MANAGEMENT L.P. | 115,000 | 955,000 | 1.24% | ||
| 16 | WEXFORD CAPITAL LP | 100,000 | 830,000 | 1.08% | ||
| 17 | Iguana Healthcare Management, LLC | 63,833 | 530,000 | 0.69% | ||
| 18 | DEUTSCHE BANK AG\ | 41,285 | 342,000 | 0.44% | ||
| 19 | HIGHLAND CAPITAL MANAGEMENT LP | 34,975 | 290,000 | 0.38% | ||
| 20 | Ghost Tree Capital, LLC | 23,500 | 195,000 | 0.25% | ||
| 21 | PRELUDE CAPITAL MANAGEMENT, LLC | 4,467 | 37,000 | 0.05% | ||
| 22 | NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 3,800 | 32,000 | 0.04% | ||
| 23 | Tower Research Capital LLC (TRC) | 600 | 5,000 | 0.01% | ||
| 24 | MORGAN STANLEY | 31 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
