| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Lombard Odier Asset Management (USA) Corp | 1,898,846 | 18,894,000 | 14.81% | ||
| 2 | ARMISTICE CAPITAL, LLC | 1,780,000 | 17,711,000 | 13.88% | ||
| 3 | Broadfin Capital, LLC | 1,741,700 | 17,330,000 | 13.58% | ||
| 4 | FMR LLC | 1,429,609 | 14,225,000 | 11.15% | ||
| 5 | JPMORGAN CHASE & CO | 1,040,003 | 10,347,000 | 8.11% | ||
| 6 | MILLENNIUM MANAGEMENT LLC | 776,118 | 7,722,000 | 6.05% | ||
| 7 | Visium Asset Management, LP | 641,251 | 6,380,000 | 5.00% | ||
| 8 | BAKER BROS. ADVISORS LP | 571,000 | 5,681,000 | 4.45% | ||
| 9 | Artal Group S.A. | 425,000 | 4,229,000 | 3.32% | ||
| 10 | BALYASNY ASSET MANAGEMENT L.P. | 351,826 | 3,501,000 | 2.74% | ||
| 11 | Foresite Capital Management I, LLC | 336,766 | 3,351,000 | 2.63% | ||
| 12 | VANGUARD GROUP INC | 310,625 | 3,091,000 | 2.42% | ||
| 13 | SABBY MANAGEMENT, LLC | 259,032 | 2,577,000 | 2.02% | ||
| 14 | Ghost Tree Capital, LLC | 250,000 | 2,488,000 | 1.95% | ||
| 15 | Avoro Capital Advisors LLC | 200,772 | 1,998,000 | 1.57% | ||
| 16 | Foresite Capital Management II, LLC | 185,220 | 1,843,000 | 1.44% | ||
| 17 | BAILARD, INC. | 160,000 | 1,592,000 | 1.25% | ||
| 18 | GEODE CAPITAL MANAGEMENT, LLC | 120,227 | 1,196,000 | 0.94% | ||
| 19 | ACUTA CAPITAL PARTNERS, LLC | 100,000 | 995,000 | 0.78% | ||
| 20 | BlackRock Fund Advisors | 39,384 | 392,000 | 0.31% | ||
| 21 | Spark Investment Management LLC | 26,300 | 260,000 | 0.20% | ||
| 22 | GUPTA WEALTH MANAGEMENT LLC | 23,719 | 236,000 | 0.18% | ||
| 23 | TFS CAPITAL LLC | 18,159 | 181,000 | 0.14% | ||
| 24 | GOLDMAN SACHS GROUP INC | 17,309 | 172,000 | 0.13% | ||
| 25 | STATE STREET CORP | 17,000 | 169,000 | 0.13% | ||
| 26 | Nationwide Fund Advisors | 15,000 | 149,000 | 0.12% | ||
| 27 | DRW Securities, LLC | 15,000 | 149,000 | 0.12% | ||
| 28 | Virtu KCG Holdings LLC | 11,202 | 111,000 | 0.09% | ||
| 29 | BlackRock Institutional Trust Company, N.A. | 10,700 | 106,000 | 0.08% | ||
| 30 | RENAISSANCE TECHNOLOGIES LLC | 10,600 | 105,000 | 0.08% | ||
| 31 | NORTHERN TRUST CORP | 10,213 | 102,000 | 0.08% | ||
| 32 | Independence Capital Asset Partners, LLC | 10,000 | 99,000 | 0.08% | ||
| 33 | BlackRock Group LTD | 4,995 | 50,000 | 0.04% | ||
| 34 | MORGAN STANLEY | 4,909 | 49,000 | 0.04% | ||
| 35 | BlackRock Japan Co. Ltd | 3,958 | 39,000 | 0.03% | ||
| 36 | BlackRock Investment Management, LLC | 3,050 | 30,000 | 0.02% | ||
| 37 | BLACKROCK ADVISORS LLC | 1,250 | 12,000 | 0.01% | ||
| 38 | Tower Research Capital LLC (TRC) | 605 | 6,000 | 0.00% | ||
| 39 | CITIGROUP INC | 20 | 0 | 0.00% | ||
| 40 | ROYAL BANK OF CANADA | 14 | 0 | 0.00% | ||
| 41 | UBS Group AG | 8 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
