| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Novo Holdings A/S | 3,549,320 | 212,604,000 | 15.90% | ||
| 2 | BROWN CAPITAL MANAGEMENT LLC | 1,224,464 | 73,345,000 | 5.48% | ||
| 3 | BlackRock Fund Advisors | 1,179,565 | 70,656,000 | 5.28% | ||
| 4 | VANGUARD GROUP INC | 1,040,504 | 62,326,000 | 4.66% | ||
| 5 | BLAIR WILLIAM & CO/IL | 912,789 | 54,676,000 | 4.09% | ||
| 6 | TimesSquare Capital Management, LLC | 726,565 | 43,521,000 | 3.25% | ||
| 7 | WADDELL & REED FINANCIAL INC | 609,200 | 36,491,000 | 2.73% | ||
| 8 | DIMENSIONAL FUND ADVISORS LP | 491,170 | 29,421,000 | 2.20% | ||
| 9 | WELLS FARGO & COMPANY/MN | 477,657 | 28,612,000 | 2.14% | ||
| 10 | JPMORGAN CHASE & CO | 443,200 | 26,548,000 | 1.99% | ||
| 11 | OppenheimerFunds, Inc. | 426,412 | 25,542,000 | 1.91% | ||
| 12 | PEREGRINE CAPITAL MANAGEMENT INC /MN/ | 416,770 | 24,965,000 | 1.87% | ||
| 13 | Cortina Asset Management, LLC | 408,733 | 24,483,000 | 1.83% | ||
| 14 | WELLINGTON MANAGEMENT GROUP LLP | 408,152 | 24,449,000 | 1.83% | ||
| 15 | KALMAR INVESTMENTS INC /DE/ | 404,990 | 24,259,000 | 1.81% | ||
| 16 | LOOMIS SAYLES & CO L P | 403,633 | 24,178,000 | 1.81% | ||
| 17 | BlackRock Institutional Trust Company, N.A. | 394,884 | 23,654,000 | 1.77% | ||
| 18 | STATE STREET CORP | 348,872 | 20,902,000 | 1.56% | ||
| 19 | Granahan Investment Management, LLC | 330,201 | 19,779,000 | 1.48% | ||
| 20 | NEXT CENTURY GROWTH INVESTORS LLC | 303,771 | 18,195,000 | 1.36% | ||
| 21 | ROCKEFELLER FINANCIAL SERVICES INC | 295,558 | 17,704,000 | 1.32% | ||
| 22 | Invesco Ltd. | 287,433 | 17,217,000 | 1.29% | ||
| 23 | NORGES BANK | 297,879 | 17,042,000 | 1.27% | ||
| 24 | Bank of New York Mellon Corp | 273,744 | 16,398,000 | 1.23% | ||
| 25 | PRICE T ROWE ASSOCIATES INC /MD/ | 271,740 | 16,277,000 | 1.22% | ||
| 26 | ROYAL BANK OF CANADA | 259,812 | 15,562,000 | 1.16% | ||
| 27 | Point72 Asset Management, L.P. | 259,590 | 15,549,000 | 1.16% | ||
| 28 | NORTHERN TRUST CORP | 240,670 | 14,416,000 | 1.08% | ||
| 29 | DRIEHAUS CAPITAL MANAGEMENT LLC | 216,740 | 12,983,000 | 0.97% | ||
| 30 | KORNITZER CAPITAL MANAGEMENT INC /KS | 212,985 | 12,758,000 | 0.95% | ||
| 31 | NEW YORK STATE COMMON RETIREMENT FUND | 211,440 | 12,665,000 | 0.95% | ||
| 32 | FMR LLC | 200,300 | 11,998,000 | 0.90% | ||
| 33 | THRIVENT FINANCIAL FOR LUTHERANS | 198,270 | 11,876,000 | 0.89% | ||
| 34 | FRED ALGER MANAGEMENT, LLC | 188,585 | 11,296,000 | 0.84% | ||
| 35 | RENAISSANCE TECHNOLOGIES LLC | 181,500 | 10,872,000 | 0.81% | ||
| 36 | GOLDMAN SACHS GROUP INC | 176,918 | 10,598,000 | 0.79% | ||
| 37 | Allianz Asset Management GmbH | 176,759 | 10,588,000 | 0.79% | ||
| 38 | TIRSCHWELL & LOEWY INC | 174,150 | 10,432,000 | 0.78% | ||
| 39 | COLUMBUS CIRCLE INVESTORS | 159,493 | 9,554,000 | 0.71% | ||
| 40 | GEODE CAPITAL MANAGEMENT, LLC | 149,244 | 8,939,000 | 0.67% | ||
| 41 | AMERIPRISE FINANCIAL INC | 141,020 | 8,447,000 | 0.63% | ||
| 42 | LORD, ABBETT & CO. LLC | 139,476 | 8,354,000 | 0.62% | ||
| 43 | Pembroke Management, LTD | 138,100 | 8,272,000 | 0.62% | ||
| 44 | OBERWEIS ASSET MANAGEMENT INC/ | 129,050 | 7,730,000 | 0.58% | ||
| 45 | PRINCIPAL FINANCIAL GROUP INC | 119,879 | 7,181,000 | 0.54% | ||
| 46 | DEUTSCHE BANK AG\ | 116,207 | 6,959,000 | 0.52% | ||
| 47 | ROYCE & ASSOCIATES LP | 113,155 | 6,778,000 | 0.51% | ||
| 48 | THORNBURG INVESTMENT MANAGEMENT INC | 110,416 | 6,614,000 | 0.49% | ||
| 49 | CREDIT AGRICOLE S A | 110,000 | 6,589,000 | 0.49% | ||
| 50 | TIAA CREF INVESTMENT MANAGEMENT LLC | 98,948 | 5,927,000 | 0.44% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
