| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 1,753,573 | 23,831,000 | 51.24% | ||
| 2 | First Eagle Investment Management, LLC | 352,000 | 4,784,000 | 10.29% | ||
| 3 | SABBY MANAGEMENT, LLC | 225,081 | 3,059,000 | 6.58% | ||
| 4 | BLACKROCK ADVISORS LLC | 128,100 | 1,741,000 | 3.74% | ||
| 5 | BVF INC/IL | 125,000 | 1,699,000 | 3.65% | ||
| 6 | AXA S.A. | 105,961 | 1,440,000 | 3.10% | ||
| 7 | MILLENNIUM MANAGEMENT LLC | 105,242 | 1,430,000 | 3.07% | ||
| 8 | COLUMBUS CIRCLE INVESTORS | 99,679 | 1,355,000 | 2.91% | ||
| 9 | PUTNAM INVESTMENTS LLC | 96,061 | 1,305,000 | 2.81% | ||
| 10 | DEUTSCHE BANK AG\ | 92,125 | 1,250,000 | 2.69% | ||
| 11 | WALL STREET ASSOCIATES | 55,000 | 747,000 | 1.61% | ||
| 12 | FARALLON CAPITAL MANAGEMENT LLC | 50,000 | 680,000 | 1.46% | ||
| 13 | BlackRock Group LTD | 43,800 | 595,000 | 1.28% | ||
| 14 | JENNISON ASSOCIATES LLC | 31,800 | 432,000 | 0.93% | ||
| 15 | BAKER BROS. ADVISORS LP | 30,672 | 417,000 | 0.90% | ||
| 16 | BlackRock Finance, Inc. | 26,800 | 364,000 | 0.78% | ||
| 17 | Granite Point Capital Management, L.P. | 25,000 | 340,000 | 0.73% | ||
| 18 | EVENTIDE ASSET MANAGEMENT, LLC | 21,466 | 292,000 | 0.63% | ||
| 19 | TFS CAPITAL LLC | 15,563 | 212,000 | 0.46% | ||
| 20 | Alyeska Investment Group, L.P. | 12,620 | 172,000 | 0.37% | ||
| 21 | DRIEHAUS CAPITAL MANAGEMENT LLC | 12,213 | 166,000 | 0.36% | ||
| 22 | HighTower Advisors, LLC | 10,000 | 136,000 | 0.29% | ||
| 23 | MORGAN STANLEY | 2,089 | 28,000 | 0.06% | ||
| 24 | THOMPSON DAVIS & CO., INC. | 2,000 | 27,000 | 0.06% | ||
| 25 | Tower Research Capital LLC (TRC) | 431 | 6,000 | 0.01% | ||
| 26 | WELLS FARGO & COMPANY/MN | 300 | 4,000 | 0.01% | ||
| 27 | CITIGROUP INC | 25 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
