| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | PERCEPTIVE ADVISORS LLC | 1,312,836 | 10,043,000 | 18.50% | ||
| 2 | FMR LLC | 1,128,918 | 8,637,000 | 15.91% | ||
| 3 | Point72 Asset Management, L.P. | 586,545 | 4,487,000 | 8.27% | ||
| 4 | ORBIMED ADVISORS LLC | 489,000 | 3,741,000 | 6.89% | ||
| 5 | PUTNAM INVESTMENTS LLC | 340,849 | 2,607,000 | 4.80% | ||
| 6 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 327,809 | 2,508,000 | 4.62% | ||
| 7 | BlackRock Fund Advisors | 324,462 | 2,482,000 | 4.57% | ||
| 8 | MORGAN STANLEY | 286,413 | 2,190,000 | 4.03% | ||
| 9 | Spark Investment Management LLC | 279,100 | 2,135,000 | 3.93% | ||
| 10 | Tekla Capital Management LLC | 241,021 | 1,844,000 | 3.40% | ||
| 11 | RENAISSANCE TECHNOLOGIES LLC | 235,350 | 1,800,000 | 3.32% | ||
| 12 | BAKER BROS. ADVISORS LP | 230,000 | 1,760,000 | 3.24% | ||
| 13 | DAFNA Capital Management LLC | 203,907 | 1,560,000 | 2.87% | ||
| 14 | BOGLE INVESTMENT MANAGEMENT L P /DE/ | 165,738 | 1,267,000 | 2.33% | ||
| 15 | BANK OF AMERICA CORP /DE/ | 142,560 | 1,091,000 | 2.01% | ||
| 16 | DEUTSCHE BANK AG\ | 112,474 | 860,000 | 1.58% | ||
| 17 | ASCEND CAPITAL, LLC | 100,000 | 765,000 | 1.41% | ||
| 18 | MACQUARIE GROUP LTD | 80,000 | 612,000 | 1.13% | ||
| 19 | BlackRock Institutional Trust Company, N.A. | 70,322 | 538,000 | 0.99% | ||
| 20 | TFS CAPITAL LLC | 62,988 | 482,000 | 0.89% | ||
| 21 | GOLDMAN SACHS GROUP INC | 41,918 | 321,000 | 0.59% | ||
| 22 | JPMORGAN CHASE & CO | 31,340 | 240,000 | 0.44% | ||
| 23 | FT OPTIONS LLC | 30,158 | 231,000 | 0.43% | ||
| 24 | VIRTUS ETF ADVISERS LLC | 26,511 | 203,000 | 0.37% | ||
| 25 | LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 21,574 | 165,000 | 0.30% | ||
| 26 | Palo Alto Investors LP | 20,453 | 156,000 | 0.29% | ||
| 27 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 20,000 | 153,000 | 0.28% | ||
| 28 | CITADEL ADVISORS LLC | 18,500 | 142,000 | 0.26% | Call | |
| 29 | ProShare Advisors LLC | 15,656 | 120,000 | 0.22% | ||
| 30 | CAPITAL FUND MANAGEMENT S.A. | 14,500 | 111,000 | 0.20% | ||
| 31 | ELLINGTON MANAGEMENT GROUP LLC | 14,100 | 108,000 | 0.20% | ||
| 32 | BOOTHBAY FUND MANAGEMENT, LLC | 13,450 | 103,000 | 0.19% | ||
| 33 | CREDIT SUISSE AG/ | 13,253 | 102,000 | 0.19% | ||
| 34 | WEDBUSH SECURITIES INC | 12,600 | 96,000 | 0.18% | ||
| 35 | Creative Planning | 11,995 | 92,000 | 0.17% | ||
| 36 | MILLENNIUM MANAGEMENT LLC | 10,657 | 82,000 | 0.15% | ||
| 37 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 10,535 | 81,000 | 0.15% | ||
| 38 | Compagnie Lombard Odier SCmA | 10,000 | 76,000 | 0.14% | ||
| 39 | CUTLER GROUP LLC / CA | 8,260 | 63,000 | 0.12% | ||
| 40 | UBS Group AG | 4,600 | 35,000 | 0.06% | ||
| 41 | PRELUDE CAPITAL MANAGEMENT, LLC | 4,500 | 34,000 | 0.06% | ||
| 42 | Tower Research Capital LLC (TRC) | 4,386 | 34,000 | 0.06% | ||
| 43 | CITIGROUP INC | 4,003 | 31,000 | 0.06% | ||
| 44 | WELLS FARGO & COMPANY/MN | 3,000 | 23,000 | 0.04% | ||
| 45 | ADVISOR GROUP, INC. | 2,616 | 20,000 | 0.04% | ||
| 46 | CUTLER GROUP LLC / CA | 3,000 | 16,000 | 0.03% | Put | |
| 47 | GROUP ONE TRADING LLC | 1,929 | 15,000 | 0.03% | ||
| 48 | ROYAL BANK OF CANADA | 1,267 | 10,000 | 0.02% | ||
| 49 | SIMPLEX TRADING, LLC | 1,109 | 8,000 | 0.01% | ||
| 50 | Cubist Systematic Strategies, LLC | 921 | 7,000 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
