| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 2,143,006 | 57,861,000 | 27.80% | ||
| 2 | PERCEPTIVE ADVISORS LLC | 650,269 | 17,557,000 | 8.44% | ||
| 3 | SECTORAL ASSET MANAGEMENT INC | 649,800 | 17,545,000 | 8.43% | ||
| 4 | Point72 Asset Management, L.P. | 546,313 | 14,750,000 | 7.09% | ||
| 5 | Tourbillon Capital Partners, L.P. | 540,000 | 14,580,000 | 7.01% | ||
| 6 | MILLENNIUM MANAGEMENT LLC | 347,037 | 9,370,000 | 4.50% | ||
| 7 | PUTNAM INVESTMENTS LLC | 346,662 | 9,360,000 | 4.50% | ||
| 8 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 326,600 | 8,818,000 | 4.24% | ||
| 9 | LORD, ABBETT & CO. LLC | 217,656 | 5,876,000 | 2.82% | ||
| 10 | Granite Investment Partners, LLC | 205,572 | 5,550,000 | 2.67% | ||
| 11 | Ghost Tree Capital, LLC | 185,000 | 4,995,000 | 2.40% | ||
| 12 | EverPoint Asset Management, LLC | 175,000 | 4,725,000 | 2.27% | ||
| 13 | J. Goldman & Co LP | 169,947 | 4,589,000 | 2.21% | ||
| 14 | OppenheimerFunds, Inc. | 158,720 | 4,285,000 | 2.06% | ||
| 15 | SPHERA FUNDS MANAGEMENT LTD. | 115,000 | 3,105,000 | 1.49% | ||
| 16 | EVENTIDE ASSET MANAGEMENT, LLC | 90,500 | 2,444,000 | 1.17% | ||
| 17 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 72,700 | 1,963,000 | 0.94% | ||
| 18 | WALL STREET ASSOCIATES | 55,000 | 1,485,000 | 0.71% | ||
| 19 | PDT Partners, LLC | 53,300 | 1,439,000 | 0.69% | ||
| 20 | Spark Investment Management LLC | 51,800 | 1,398,000 | 0.67% | ||
| 21 | HARVEY CAPITAL MANAGEMENT INC | 43,465 | 1,152,000 | 0.55% | ||
| 22 | DEUTSCHE BANK AG\ | 40,000 | 1,080,000 | 0.52% | ||
| 23 | DAFNA Capital Management LLC | 40,000 | 1,080,000 | 0.52% | SH | |
| 24 | ACADIAN ASSET MANAGEMENT LLC | 38,585 | 1,041,000 | 0.50% | ||
| 25 | CITADEL ADVISORS LLC | 33,580 | 907,000 | 0.44% | ||
| 26 | Informed Momentum Co LLC | 32,914 | 889,000 | 0.43% | ||
| 27 | Trexquant Investment LP | 30,600 | 826,000 | 0.40% | ||
| 28 | BAKER BROS. ADVISORS LP | 30,000 | 810,000 | 0.39% | ||
| 29 | CQS Cayman LP | 30,000 | 810,000 | 0.39% | ||
| 30 | Bank of New York Mellon Corp | 29,661 | 801,000 | 0.38% | ||
| 31 | D. E. Shaw & Co., Inc. | 25,100 | 678,000 | 0.33% | ||
| 32 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 23,304 | 629,000 | 0.30% | ||
| 33 | COLUMBUS CIRCLE INVESTORS | 22,587 | 610,000 | 0.29% | ||
| 34 | Nine Chapters Capital Management LLC | 22,200 | 599,000 | 0.29% | ||
| 35 | NEW YORK STATE COMMON RETIREMENT FUND | 21,439 | 579,000 | 0.28% | ||
| 36 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 21,400 | 578,000 | 0.28% | Put | |
| 37 | AMERIPRISE FINANCIAL INC | 21,034 | 568,000 | 0.27% | ||
| 38 | NAVELLIER & ASSOCIATES INC | 16,849 | 455,000 | 0.22% | ||
| 39 | COWEN INC. | 16,000 | 432,000 | 0.21% | ||
| 40 | CITIGROUP INC | 14,916 | 403,000 | 0.19% | ||
| 41 | MORGAN STANLEY | 10,050 | 271,000 | 0.13% | ||
| 42 | FolioMetrix LLC | 8,100 | 240,000 | 0.12% | ||
| 43 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 8,400 | 227,000 | 0.11% | Call | |
| 44 | Cubist Systematic Strategies, LLC | 8,243 | 223,000 | 0.11% | ||
| 45 | CREDIT SUISSE AG/ | 8,096 | 219,000 | 0.11% | ||
| 46 | PRELUDE CAPITAL MANAGEMENT, LLC | 3,500 | 95,000 | 0.05% | ||
| 47 | UBS Group AG | 2,986 | 81,000 | 0.04% | ||
| 48 | WELLS FARGO & COMPANY/MN | 2,000 | 54,000 | 0.03% | ||
| 49 | ROYAL BANK OF CANADA | 1,000 | 27,000 | 0.01% | ||
| 50 | Stevens First Principles Investment Advisors | 600 | 16,000 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
