| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 1,759,451 | 42,790,000 | 35.75% | ||
| 2 | PERCEPTIVE ADVISORS LLC | 1,039,332 | 25,227,000 | 21.07% | ||
| 3 | Tourbillon Capital Partners, L.P. | 300,000 | 7,296,000 | 6.10% | ||
| 4 | Granite Investment Partners, LLC | 242,717 | 5,902,000 | 4.93% | ||
| 5 | Avoro Capital Advisors LLC | 226,456 | 5,507,000 | 4.60% | ||
| 6 | MILLENNIUM MANAGEMENT LLC | 195,248 | 4,748,000 | 3.97% | ||
| 7 | OppenheimerFunds, Inc. | 158,720 | 3,860,000 | 3.22% | ||
| 8 | SPHERA FUNDS MANAGEMENT LTD. | 102,415 | 2,491,000 | 2.08% | ||
| 9 | PUTNAM INVESTMENTS LLC | 96,061 | 2,336,000 | 1.95% | ||
| 10 | EVENTIDE ASSET MANAGEMENT, LLC | 90,500 | 2,201,000 | 1.84% | ||
| 11 | First Eagle Investment Management, LLC | 89,300 | 2,172,000 | 1.81% | ||
| 12 | MORGAN STANLEY | 71,136 | 1,730,000 | 1.45% | ||
| 13 | CQS Cayman LP | 59,400 | 1,445,000 | 1.21% | ||
| 14 | WALL STREET ASSOCIATES | 55,000 | 1,338,000 | 1.12% | ||
| 15 | Spark Investment Management LLC | 51,800 | 1,252,000 | 1.05% | ||
| 16 | NORTHERN TRUST CORP | 37,829 | 920,000 | 0.77% | ||
| 17 | Informed Momentum Co LLC | 32,914 | 800,000 | 0.67% | ||
| 18 | DAFNA Capital Management LLC | 30,000 | 730,000 | 0.61% | SH | |
| 19 | BAKER BROS. ADVISORS LP | 30,000 | 730,000 | 0.61% | ||
| 20 | DEUTSCHE BANK AG\ | 30,000 | 729,000 | 0.61% | ||
| 21 | Bank of New York Mellon Corp | 29,661 | 721,000 | 0.60% | ||
| 22 | COLUMBUS CIRCLE INVESTORS | 29,072 | 707,000 | 0.59% | ||
| 23 | HARVEY CAPITAL MANAGEMENT INC | 22,100 | 537,000 | 0.45% | ||
| 24 | NEW YORK STATE COMMON RETIREMENT FUND | 21,439 | 521,000 | 0.44% | ||
| 25 | BALYASNY ASSET MANAGEMENT L.P. | 21,038 | 512,000 | 0.43% | ||
| 26 | PDT Partners, LLC | 18,900 | 460,000 | 0.38% | ||
| 27 | A.R.T. Advisors, LLC | 18,295 | 444,000 | 0.37% | ||
| 28 | CITADEL ADVISORS LLC | 14,735 | 358,000 | 0.30% | ||
| 29 | ROYAL BANK OF CANADA | 10,100 | 245,000 | 0.20% | ||
| 30 | BNP Paribas Asset Management Holding S.A. | 9,979 | 243,000 | 0.20% | ||
| 31 | CREDIT SUISSE AG/ | 9,163 | 222,000 | 0.19% | ||
| 32 | Trexquant Investment LP | 8,868 | 215,000 | 0.18% | ||
| 33 | ACADIAN ASSET MANAGEMENT LLC | 7,510 | 183,000 | 0.15% | ||
| 34 | PRELUDE CAPITAL MANAGEMENT, LLC | 3,200 | 78,000 | 0.07% | ||
| 35 | UBS Group AG | 525 | 13,000 | 0.01% | ||
| 36 | WELLS FARGO & COMPANY/MN | 500 | 12,000 | 0.01% | ||
| 37 | PNC FINANCIAL SERVICES GROUP, INC. | 500 | 12,000 | 0.01% | ||
| 38 | MAGEE THOMSON INVESTMENT PARTNERS LLC | 349 | 9,000 | 0.01% | ||
| 39 | Tower Research Capital LLC (TRC) | 192 | 5,000 | 0.00% | ||
| 40 | SUMMIT SECURITIES GROUP LLC | 100 | 2,000 | 0.00% | ||
| 41 | CITIGROUP INC | 5 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
