| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Temasek Holdings (Private) Ltd | 6,583,568 | 258,010,000 | 13.14% | ||
| 2 | WELLINGTON MANAGEMENT GROUP LLP | 5,433,434 | 212,936,000 | 10.84% | ||
| 3 | VANGUARD GROUP INC | 4,614,814 | 180,855,000 | 9.21% | ||
| 4 | BlackRock Finance, Inc. | 4,034,725 | 158,121,000 | 8.05% | ||
| 5 | FMR LLC | 3,902,000 | 152,919,000 | 7.79% | ||
| 6 | STATE STREET CORP | 1,980,631 | 77,622,000 | 3.95% | ||
| 7 | PFM Health Sciences, LP | 1,692,510 | 66,329,000 | 3.38% | ||
| 8 | DEERFIELD MANAGEMENT COMPANY, L.P. | 1,451,301 | 56,876,000 | 2.90% | ||
| 9 | JPMORGAN CHASE & CO | 1,064,192 | 41,705,000 | 2.12% | ||
| 10 | CADIAN CAPITAL MANAGEMENT, LP | 868,400 | 34,033,000 | 1.73% | ||
| 11 | FRED ALGER MANAGEMENT, LLC | 731,015 | 28,648,000 | 1.46% | ||
| 12 | D. E. Shaw & Co., Inc. | 655,490 | 25,688,000 | 1.31% | ||
| 13 | BALYASNY ASSET MANAGEMENT L.P. | 635,645 | 24,911,000 | 1.27% | ||
| 14 | PICTET ASSET MANAGEMENT LTD | 630,858 | 24,723,000 | 1.26% | ||
| 15 | NORTHERN TRUST CORP | 616,279 | 24,152,000 | 1.23% | ||
| 16 | SECTORAL ASSET MANAGEMENT INC | 604,041 | 23,672,000 | 1.21% | ||
| 17 | Cormorant Asset Management, LP | 600,000 | 23,514,000 | 1.20% | ||
| 18 | MORGAN STANLEY | 555,747 | 21,780,000 | 1.11% | ||
| 19 | Tourbillon Capital Partners, L.P. | 528,903 | 20,728,000 | 1.06% | ||
| 20 | PINNACLE ASSOCIATES LTD | 526,176 | 20,621,000 | 1.05% | ||
| 21 | GOLDMAN SACHS GROUP INC | 517,046 | 20,263,000 | 1.03% | ||
| 22 | GEODE CAPITAL MANAGEMENT, LLC | 481,732 | 18,879,000 | 0.96% | ||
| 23 | NORGES BANK | 435,947 | 17,085,000 | 0.87% | ||
| 24 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 399,684 | 15,663,616 | 0.80% | ||
| 25 | DEUTSCHE BANK AG\ | 391,571 | 15,343,000 | 0.78% | ||
| 26 | VOYA INVESTMENT MANAGEMENT LLC | 386,690 | 15,155,000 | 0.77% | ||
| 27 | FARALLON CAPITAL MANAGEMENT LLC | 385,000 | 15,088,000 | 0.77% | ||
| 28 | ALLIANCEBERNSTEIN L.P. | 371,373 | 14,554,000 | 0.74% | ||
| 29 | BOGLE INVESTMENT MANAGEMENT L P /DE/ | 330,318 | 12,945,000 | 0.66% | ||
| 30 | EMERALD ADVISERS, LLC | 291,993 | 11,443,000 | 0.58% | ||
| 31 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 271,900 | 10,656,000 | 0.54% | Put | |
| 32 | CITADEL ADVISORS LLC | 270,033 | 10,583,000 | 0.54% | ||
| 33 | ZEVENBERGEN CAPITAL INVESTMENTS LLC | 263,870 | 10,341,000 | 0.53% | ||
| 34 | TEACHERS ADVISORS, LLC | 259,325 | 10,163,000 | 0.52% | ||
| 35 | MILLENNIUM MANAGEMENT LLC | 255,190 | 10,001,000 | 0.51% | ||
| 36 | Bank of New York Mellon Corp | 250,723 | 9,825,000 | 0.50% | ||
| 37 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 250,500 | 9,817,000 | 0.50% | Call | |
| 38 | Allianz Asset Management GmbH | 248,265 | 9,709,000 | 0.49% | ||
| 39 | Fernwood Investment Management, LLC | 227,902 | 8,931,000 | 0.45% | ||
| 40 | TIAA CREF INVESTMENT MANAGEMENT LLC | 223,924 | 8,776,000 | 0.45% | ||
| 41 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 221,223 | 8,670,000 | 0.44% | ||
| 42 | EMERALD MUTUAL FUND ADVISERS TRUST | 215,441 | 8,443,000 | 0.43% | ||
| 43 | Ghost Tree Capital, LLC | 200,000 | 7,838,000 | 0.40% | ||
| 44 | HARVEY CAPITAL MANAGEMENT INC | 194,380 | 7,617,000 | 0.39% | ||
| 45 | STRS OHIO | 191,100 | 7,489,000 | 0.38% | ||
| 46 | BANK OF AMERICA CORP /DE/ | 180,965 | 7,092,000 | 0.36% | ||
| 47 | PRUDENTIAL FINANCIAL INC | 155,740 | 6,104,000 | 0.31% | ||
| 48 | CREDIT SUISSE AG/ | 154,411 | 6,051,000 | 0.31% | ||
| 49 | GAM Holding AG | 151,600 | 5,941,000 | 0.30% | ||
| 50 | Randolph Co Inc | 125,200 | 4,907,000 | 0.25% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
