| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ABIOMED INC | 2,889,505 | 260,865,000 | 14.52% | ||
| 2 | Anacor Pharmaceuticals Inc | 2,187,242 | 247,093,000 | 13.75% | ||
| 3 | UNITED THERAPEUTICS | 1,518,654 | 237,836,000 | 13.24% | ||
| 4 | BIOMARIN | 1,336,847 | 140,048,000 | 7.79% | ||
| 5 | CLOVIS ONCOLOGY INC | 3,547,719 | 124,170,000 | 6.91% | ||
| 6 | INSMED INC COM PAR .01 | 4,790,800 | 86,953,000 | 4.84% | ||
| 7 | AMAG PHARMACEUTICALS INC COM | 2,835,792 | 85,613,000 | 4.77% | ||
| 8 | Wright Medical Group NV | 2,132,157 | 51,556,000 | 2.87% | ||
| 9 | ENDO INTL | 801,230 | 49,051,000 | 2.73% | ||
| 10 | PROTHENA CORP PLC | 695,518 | 47,372,000 | 2.64% | ||
| 11 | EPIZYME INC COM | 2,660,979 | 42,629,000 | 2.37% | ||
| 12 | KARYOPHARM THERAPEUTICS INC COM | 3,112,645 | 41,243,000 | 2.30% | ||
| 13 | VANDA PHARMACEUTICALS INC COM | 4,030,908 | 37,528,000 | 2.09% | ||
| 14 | CEMPRA INC | 1,175,733 | 36,601,000 | 2.04% | ||
| 15 | AMICUS THERAPEUTICS INC | 3,551,173 | 34,446,000 | 1.92% | ||
| 16 | CELGENE CORP | 270,800 | 32,431,000 | 1.81% | ||
| 17 | GILEAD SCIENCES INC | 302,900 | 30,650,000 | 1.71% | ||
| 18 | MEDIVATION INC | 509,862 | 24,647,000 | 1.37% | ||
| 19 | Momenta Pharmaceuticals Inc | 1,468,776 | 21,797,000 | 1.21% | ||
| 20 | SHIRE PLC | 104,700 | 21,464,000 | 1.19% | ||
| 21 | STAAR SURGICAL CO | 2,666,722 | 19,040,000 | 1.06% | ||
| 22 | SEQUENOM INC | 10,023,842 | 16,439,000 | 0.91% | ||
| 23 | ZELTIQ AESTHETICS INCORPORATED | 573,636 | 16,366,000 | 0.91% | ||
| 24 | RIGEL PHARMACEUTICAL INC | 5,239,119 | 15,875,000 | 0.88% | ||
| 25 | ARIAD PHARMACEUTICALS INC | 2,257,217 | 14,108,000 | 0.79% | ||
| 26 | Heartware International, Inc. | 246,068 | 12,402,000 | 0.69% | ||
| 27 | ALIMERA SCIENCES INC | 3,013,793 | 7,293,000 | 0.41% | ||
| 28 | Sunesis Pharmaceuticals I | 6,974,854 | 6,260,000 | 0.35% | ||
| 29 | AIMMUNE THERAPEUTICS INC COM | 325,599 | 6,007,000 | 0.33% | ||
| 30 | ACELRX PHARMACEUTICALS INC | 1,425,439 | 5,488,000 | 0.31% | ||
| 31 | IDERA PHARMACEUTICALS INC | 1,257,748 | 3,886,000 | 0.22% | ||
| 32 | EXACT SCIENCES CORP | 396,276 | 3,658,000 | 0.20% | ||
| 33 | Dicerna Pharmaceuticals | 267,890 | 3,180,000 | 0.18% | ||
| 34 | Orexigen Therapeutics, Inc. | 1,673,024 | 2,878,000 | 0.16% | ||
| 35 | ALIGN TECHNOLOGY INC | 27,757 | 1,828,000 | 0.10% | ||
| 36 | ALCOBRA LTD | 254,188 | 1,596,000 | 0.09% | ||
| 37 | HISTOGENICS CORP | 454,545 | 1,591,000 | 0.09% | ||
| 38 | INTREXON CORP | 47,100 | 1,420,000 | 0.08% | ||
| 39 | CYTOKINETICS INC | 123,686 | 1,294,000 | 0.07% | ||
| 40 | SOPHIRIS BIO INC | 494,000 | 879,000 | 0.05% | ||
| 41 | MARINUS PHARMACEUTICALS INC | 59,017 | 451,000 | 0.03% | ||
| 42 | ZOGENIX INC | 28,600 | 422,000 | 0.02% | ||
| 43 | UNIQURE NV | 20,453 | 338,000 | 0.02% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001306923-16-000045, filed 2016.02.16).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
