| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Broadfin Capital, LLC | 8,200,000 | 15,990,000 | 39.67% | ||
| 2 | BAKER BROS. ADVISORS LP | 5,102,153 | 9,949,000 | 24.68% | ||
| 3 | VANGUARD GROUP INC | 3,007,935 | 5,865,000 | 14.55% | ||
| 4 | Candriam S.C.A. | 600,000 | 1,170,000 | 2.90% | ||
| 5 | BlackRock Finance, Inc. | 552,803 | 1,077,000 | 2.67% | ||
| 6 | GEODE CAPITAL MANAGEMENT, LLC | 462,677 | 902,000 | 2.24% | ||
| 7 | RENAISSANCE TECHNOLOGIES LLC | 382,400 | 746,000 | 1.85% | ||
| 8 | KNOTT DAVID M | 284,350 | 554,000 | 1.37% | ||
| 9 | CORRADO ADVISORS, LLC | 251,025 | 489,000 | 1.21% | ||
| 10 | KENNEDY CAPITAL MANAGEMENT LLC | 230,500 | 449,000 | 1.11% | ||
| 11 | TANAKA CAPITAL MANAGEMENT INC | 241,753 | 416,000 | 1.03% | ||
| 12 | ROYAL BANK OF CANADA | 165,000 | 322,000 | 0.80% | ||
| 13 | DEUTSCHE BANK AG\ | 136,788 | 266,000 | 0.66% | ||
| 14 | BOOTHBAY FUND MANAGEMENT, LLC | 135,872 | 265,000 | 0.66% | ||
| 15 | NORTHERN TRUST CORP | 111,328 | 217,000 | 0.54% | ||
| 16 | HAP Trading, LLC | 315,000 | 165,000 | 0.41% | Call | |
| 17 | JPMORGAN CHASE & CO | 79,470 | 155,000 | 0.38% | ||
| 18 | Bank of New York Mellon Corp | 69,176 | 135,000 | 0.33% | ||
| 19 | Weiss Multi-Strategy Advisers LLC | 68,000 | 133,000 | 0.33% | ||
| 20 | MILLENNIUM MANAGEMENT LLC | 60,067 | 117,000 | 0.29% | ||
| 21 | OXFORD ASSET MANAGEMENT LLP | 58,940 | 115,000 | 0.29% | ||
| 22 | A.R.T. Advisors, LLC | 51,207 | 99,000 | 0.25% | ||
| 23 | STATE STREET CORP | 45,300 | 88,000 | 0.22% | ||
| 24 | AGRAN LIBBIE | 44,000 | 86,000 | 0.21% | ||
| 25 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 41,332 | 81,000 | 0.20% | ||
| 26 | MORGAN STANLEY | 26,345 | 52,000 | 0.13% | ||
| 27 | GUGGENHEIM CAPITAL LLC | 24,984 | 49,000 | 0.12% | ||
| 28 | Commonwealth Equity Services, Inc | 24,090 | 47,000 | 0.12% | ||
| 29 | HBK Sorce Advisory LLC | 22,109 | 43,000 | 0.11% | ||
| 30 | WOLVERINE TRADING LP /BD | 19,000 | 38,000 | 0.09% | Call | |
| 31 | ProVise Management Group, LLC | 19,000 | 37,000 | 0.09% | ||
| 32 | GOLDMAN SACHS GROUP INC | 18,654 | 36,000 | 0.09% | ||
| 33 | CREDIT SUISSE AG/ | 16,050 | 31,000 | 0.08% | ||
| 34 | Raymond James Financial Services Advisors, Inc. | 15,500 | 30,000 | 0.07% | ||
| 35 | TWO SIGMA SECURITIES, LLC | 12,863 | 25,000 | 0.06% | ||
| 36 | Creative Planning | 10,681 | 21,000 | 0.05% | ||
| 37 | Segantii Capital Management Ltd | 6,700 | 13,000 | 0.03% | ||
| 38 | CUTLER GROUP LLC / CA | 5,646 | 11,000 | 0.03% | ||
| 39 | CITIGROUP INC | 4,088 | 8,000 | 0.02% | ||
| 40 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 3,218 | 6,000 | 0.01% | ||
| 41 | LADENBURG THALMANN FINANCIAL SERVICES INC. | 2,000 | 4,000 | 0.01% | ||
| 42 | BANK OF AMERICA CORP /DE/ | 1,459 | 3,000 | 0.01% | ||
| 43 | Tower Research Capital LLC (TRC) | 1,001 | 2,000 | 0.00% | ||
| 44 | CWM, LLC | 500 | 1,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
