| 1 |
Broadfin Capital, LLC |
8,200,000 |
8,610,000 |
34.43% |
|
|
| 2 |
BAKER BROS. ADVISORS LP |
5,102,153 |
5,357,000 |
21.42% |
|
|
| 3 |
VANGUARD GROUP INC |
2,992,335 |
3,142,000 |
12.56% |
|
|
| 4 |
Point72 Asset Management, L.P. |
2,272,816 |
2,386,000 |
9.54% |
|
|
| 5 |
Avoro Capital Advisors LLC |
1,141,149 |
1,198,000 |
4.79% |
|
|
| 6 |
KINGDON CAPITAL MANAGEMENT, L.L.C. |
756,311 |
794,000 |
3.18% |
|
|
| 7 |
TANAKA CAPITAL MANAGEMENT INC |
589,883 |
590,000 |
2.36% |
|
|
| 8 |
BlackRock Institutional Trust Company, N.A. |
469,440 |
493,000 |
1.97% |
|
|
| 9 |
GEODE CAPITAL MANAGEMENT, LLC |
461,231 |
484,000 |
1.94% |
|
|
| 10 |
MILLENNIUM MANAGEMENT LLC |
319,868 |
336,000 |
1.34% |
|
|
| 11 |
KENNEDY CAPITAL MANAGEMENT LLC |
233,171 |
245,000 |
0.98% |
|
|
| 12 |
CORRADO ADVISORS, LLC |
190,600 |
200,000 |
0.80% |
|
|
| 13 |
ROYAL BANK OF CANADA |
166,013 |
174,000 |
0.70% |
|
|
| 14 |
NORTHERN TRUST CORP |
100,396 |
105,000 |
0.42% |
|
|
| 15 |
Weiss Multi-Strategy Advisers LLC |
68,000 |
71,000 |
0.28% |
|
|
| 16 |
Bank of New York Mellon Corp |
66,772 |
70,000 |
0.28% |
|
|
| 17 |
A.R.T. Advisors, LLC |
63,300 |
66,000 |
0.26% |
|
|
| 18 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
59,541 |
63,000 |
0.25% |
|
|
| 19 |
BlackRock Fund Advisors |
58,345 |
61,000 |
0.24% |
|
|
| 20 |
Virtu KCG Holdings LLC |
54,200 |
57,000 |
0.23% |
|
|
| 21 |
STATE STREET CORP |
45,300 |
47,000 |
0.19% |
|
|
| 22 |
AGRAN LIBBIE |
44,000 |
46,000 |
0.18% |
|
|
| 23 |
GOLDMAN SACHS GROUP INC |
42,979 |
45,000 |
0.18% |
|
|
| 24 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
41,332 |
43,000 |
0.17% |
|
|
| 25 |
Private Advisor Group, LLC |
24,500 |
28,000 |
0.11% |
|
|
| 26 |
OXFORD ASSET MANAGEMENT LLP |
24,759 |
26,000 |
0.10% |
|
|
| 27 |
Commonwealth Equity Services, Inc |
24,000 |
25,000 |
0.10% |
|
|
| 28 |
HBK Sorce Advisory LLC |
21,109 |
22,000 |
0.09% |
|
|
| 29 |
GUGGENHEIM CAPITAL LLC |
21,335 |
22,000 |
0.09% |
|
|
| 30 |
ProVise Management Group, LLC |
19,000 |
20,000 |
0.08% |
|
|
| 31 |
Squarepoint Ops LLC |
18,000 |
19,000 |
0.08% |
|
|
| 32 |
Creative Planning |
16,681 |
18,000 |
0.07% |
|
|
| 33 |
CREDIT SUISSE AG/ |
16,005 |
17,000 |
0.07% |
|
|
| 34 |
Raymond James Financial Services Advisors, Inc. |
15,500 |
16,000 |
0.06% |
|
|
| 35 |
D. E. Shaw & Co., Inc. |
12,651 |
13,000 |
0.05% |
|
|
| 36 |
BLACKROCK ADVISORS LLC |
12,442 |
13,000 |
0.05% |
|
|
| 37 |
MORGAN STANLEY |
12,419 |
13,000 |
0.05% |
|
|
| 38 |
TWO SIGMA SECURITIES, LLC |
11,603 |
12,000 |
0.05% |
|
|
| 39 |
COMPTON CAPITAL MANAGEMENT INC /RI |
10,000 |
11,000 |
0.04% |
|
|
| 40 |
ACROSPIRE INVESTMENT MANAGEMENT LLC |
8,900 |
9,000 |
0.04% |
|
|
| 41 |
Tower Research Capital LLC (TRC) |
8,097 |
9,000 |
0.04% |
|
|
| 42 |
CUTLER GROUP LLC / CA |
5,646 |
5,000 |
0.02% |
|
|
| 43 |
CITIGROUP INC |
4,088 |
4,000 |
0.02% |
|
|
| 44 |
Vantage Investment Advisors, LLC |
3,000 |
3,000 |
0.01% |
|
|
| 45 |
MSI Financial Services Inc |
2,800 |
3,000 |
0.01% |
|
|
| 46 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
3,218 |
3,000 |
0.01% |
|
|
| 47 |
GENEOS WEALTH MANAGEMENT INC. |
2,500 |
2,000 |
0.01% |
|
|
| 48 |
BANK OF AMERICA CORP /DE/ |
1,860 |
2,000 |
0.01% |
|
|
| 49 |
Walleye Trading LLC |
1,900 |
2,000 |
0.01% |
|
|
| 50 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
2,000 |
2,000 |
0.01% |
|
|
