| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BAKER BROS. ADVISORS LP | 13,053,275 | 56,782,000 | 18.18% | ||
| 2 | PRIMECAP MANAGEMENT CO/CA/ | 7,800,000 | 33,930,000 | 10.86% | ||
| 3 | BlackRock Fund Advisors | 4,712,166 | 20,498,000 | 6.56% | ||
| 4 | VANGUARD GROUP INC | 4,364,830 | 18,987,000 | 6.08% | ||
| 5 | PEREGRINE CAPITAL MANAGEMENT INC /MN/ | 3,344,086 | 14,547,000 | 4.66% | ||
| 6 | ALLIANCEBERNSTEIN L.P. | 3,247,350 | 14,126,000 | 4.52% | ||
| 7 | Elk Creek Partners, LLC | 3,179,434 | 13,831,000 | 4.43% | ||
| 8 | WELLS FARGO & COMPANY/MN | 3,164,604 | 13,766,000 | 4.41% | ||
| 9 | Senvest Management, LLC | 2,729,373 | 11,873,000 | 3.80% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 2,643,277 | 11,498,000 | 3.68% | ||
| 11 | STATE STREET CORP | 1,787,312 | 7,773,000 | 2.49% | ||
| 12 | PICTET ASSET MANAGEMENT LTD | 1,460,918 | 6,355,000 | 2.03% | ||
| 13 | NORTHERN TRUST CORP | 1,223,228 | 5,322,000 | 1.70% | ||
| 14 | STEPHENS INC /AR/ | 948,190 | 4,125,000 | 1.32% | ||
| 15 | DEUTSCHE BANK AG\ | 940,732 | 4,090,000 | 1.31% | ||
| 16 | Pier Capital, LLC | 808,200 | 3,516,000 | 1.13% | ||
| 17 | GEODE CAPITAL MANAGEMENT, LLC | 794,151 | 3,454,000 | 1.11% | ||
| 18 | RAYMOND JAMES & ASSOCIATES | 784,984 | 3,415,000 | 1.09% | ||
| 19 | NORGES BANK | 783,135 | 3,407,000 | 1.09% | ||
| 20 | ARK INVESTMENT MANAGEMENT LLC | 661,815 | 2,879,000 | 0.92% | ||
| 21 | MORGAN STANLEY | 591,372 | 2,573,000 | 0.82% | ||
| 22 | Lesa Sroufe & Co | 569,762 | 2,478,000 | 0.79% | ||
| 23 | BANK OF AMERICA CORP /DE/ | 521,472 | 2,268,000 | 0.73% | ||
| 24 | DELTA LLOYD NV | 500,000 | 2,175,000 | 0.70% | ||
| 25 | Bank of New York Mellon Corp | 498,942 | 2,170,000 | 0.69% | ||
| 26 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 470,559 | 2,047,000 | 0.66% | ||
| 27 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 413,642 | 1,800,000 | 0.58% | ||
| 28 | BlackRock Investment Management, LLC | 403,102 | 1,753,000 | 0.56% | ||
| 29 | TIAA CREF INVESTMENT MANAGEMENT LLC | 398,200 | 1,732,000 | 0.55% | ||
| 30 | EMORY UNIVERSITY | 372,841 | 1,622,000 | 0.52% | ||
| 31 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 344,000 | 1,496,000 | 0.48% | Put | |
| 32 | Jefferies Group LLC | 317,500 | 1,381,000 | 0.44% | Put | |
| 33 | SALZHAUER MICHAEL | 310,190 | 1,350,000 | 0.43% | ||
| 34 | MACQUARIE GROUP LTD | 295,769 | 1,287,000 | 0.41% | ||
| 35 | Jefferies Group LLC | 290,689 | 1,264,000 | 0.40% | ||
| 36 | BAMCO INC /NY/ | 282,500 | 1,229,000 | 0.39% | ||
| 37 | AMERIPRISE FINANCIAL INC | 276,300 | 1,202,000 | 0.38% | ||
| 38 | CREDIT SUISSE AG/ | 271,036 | 1,178,000 | 0.38% | ||
| 39 | TEACHERS ADVISORS, LLC | 269,964 | 1,174,000 | 0.38% | ||
| 40 | D. E. Shaw & Co., Inc. | 269,651 | 1,173,000 | 0.38% | ||
| 41 | ROYCE & ASSOCIATES LP | 248,000 | 1,079,000 | 0.35% | ||
| 42 | Granite Investment Partners, LLC | 228,939 | 996,000 | 0.32% | ||
| 43 | FIRST MIDWEST BANK TRUST DIVISION | 223,308 | 971,000 | 0.31% | ||
| 44 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 208,846 | 908,000 | 0.29% | ||
| 45 | NEW YORK STATE COMMON RETIREMENT FUND | 207,514 | 903,000 | 0.29% | ||
| 46 | BAIRD FINANCIAL GROUP, INC. | 202,000 | 879,000 | 0.28% | ||
| 47 | FORMULA GROWTH LTD | 200,000 | 870,000 | 0.28% | ||
| 48 | STONERIDGE INVESTMENT PARTNERS LLC | 169,969 | 739,000 | 0.24% | ||
| 49 | Swiss National Bank | 158,900 | 691,000 | 0.22% | ||
| 50 | MILLENNIUM MANAGEMENT LLC | 130,029 | 566,000 | 0.18% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
