| # | % | |||||
|---|---|---|---|---|---|---|
| 51 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 275,000 | 2,329,000 | 1.27% | ||
| 52 | ORBIMED ADVISORS LLC | 300,000 | 2,541,000 | 1.39% | ||
| 53 | ROYCE & ASSOCIATES LP | 342,600 | 2,902,000 | 1.59% | ||
| 54 | PERCEPTIVE ADVISORS LLC | 343,284 | 2,908,000 | 1.59% | ||
| 55 | DAFNA Capital Management LLC | 373,918 | 3,167,000 | 1.73% | SH | |
| 56 | VANGUARD GROUP INC | 582,976 | 4,938,000 | 2.70% | ||
| 57 | BlackRock Fund Advisors | 619,345 | 5,246,000 | 2.87% | ||
| 58 | J. Goldman & Co LP | 772,649 | 6,544,000 | 3.58% | ||
| 59 | HealthCor Management, L.P. | 893,600 | 7,569,000 | 4.14% | ||
| 60 | GREAT POINT PARTNERS LLC | 977,923 | 8,283,000 | 4.53% | ||
| 61 | DEERFIELD MANAGEMENT COMPANY, L.P. | 991,040 | 8,394,000 | 4.59% | ||
| 62 | JENNISON ASSOCIATES LLC | 1,136,928 | 9,630,000 | 5.27% | ||
| 63 | Senvest Management, LLC | 1,151,926 | 9,757,000 | 5.34% | ||
| 64 | Consonance Capital Management LP | 1,632,627 | 13,828,000 | 7.56% | ||
| 65 | FMR LLC | 1,951,200 | 16,527,000 | 9.04% | ||
| 66 | Broadfin Capital, LLC | 2,130,477 | 18,045,000 | 9.87% | ||
| 67 | BAKER BROS. ADVISORS LP | 3,457,841 | 29,288,000 | 16.02% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
