| 1 |
GREAT POINT PARTNERS LLC |
1,963,777 |
7,463,000 |
33.36% |
|
|
| 2 |
VHCP Management, LLC |
703,730 |
2,674,000 |
11.95% |
|
|
| 3 |
QVT Financial LP |
590,127 |
2,242,000 |
10.02% |
|
|
| 4 |
MILLENNIUM MANAGEMENT LLC |
516,575 |
1,963,000 |
8.77% |
|
|
| 5 |
SABBY MANAGEMENT, LLC |
379,574 |
1,442,000 |
6.45% |
|
|
| 6 |
VANGUARD GROUP INC |
357,253 |
1,357,000 |
6.07% |
|
|
| 7 |
Endurant Capital Management LP |
231,141 |
878,000 |
3.92% |
|
|
| 8 |
Weiss Multi-Strategy Advisers LLC |
195,000 |
741,000 |
3.31% |
|
|
| 9 |
Opus Point Partners Management, LLC |
186,573 |
709,000 |
3.17% |
|
|
| 10 |
Ghost Tree Capital, LLC |
125,000 |
475,000 |
2.12% |
|
|
| 11 |
PURA VIDA INVESTMENTS, LLC |
117,419 |
460,000 |
2.06% |
|
|
| 12 |
TURNER INVESTMENTS LLC |
100,078 |
380,000 |
1.70% |
|
|
| 13 |
JPMORGAN CHASE & CO |
72,467 |
275,000 |
1.23% |
|
|
| 14 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
63,060 |
240,000 |
1.07% |
|
|
| 15 |
GEODE CAPITAL MANAGEMENT, LLC |
62,972 |
239,000 |
1.07% |
|
|
| 16 |
BlackRock Fund Advisors |
35,489 |
135,000 |
0.60% |
|
|
| 17 |
RENAISSANCE TECHNOLOGIES LLC |
35,200 |
134,000 |
0.60% |
|
|
| 18 |
STIFEL FINANCIAL CORP |
34,273 |
130,000 |
0.58% |
|
|
| 19 |
Bank of New York Mellon Corp |
34,136 |
129,000 |
0.58% |
|
|
| 20 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
30,711 |
117,000 |
0.52% |
|
|
| 21 |
DIMENSIONAL FUND ADVISORS LP |
12,100 |
46,000 |
0.21% |
|
|
| 22 |
GLENMEDE TRUST CO NA |
11,352 |
43,000 |
0.19% |
|
|
| 23 |
CITADEL ADVISORS LLC |
10,082 |
38,000 |
0.17% |
|
|
| 24 |
MORGAN STANLEY |
7,028 |
27,000 |
0.12% |
|
|
| 25 |
CITIGROUP INC |
3,095 |
11,000 |
0.05% |
|
|
| 26 |
BlackRock Investment Management, LLC |
2,122 |
8,000 |
0.04% |
|
|
| 27 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
1,755 |
7,000 |
0.03% |
|
|
| 28 |
WELLS FARGO & COMPANY/MN |
1,325 |
5,000 |
0.02% |
|
|
| 29 |
FIRST MANHATTAN CO. LLC. |
1,000 |
3,000 |
0.01% |
|
|
| 30 |
DEUTSCHE BANK AG\ |
367 |
1,000 |
0.00% |
|
|
| 31 |
Tower Research Capital LLC (TRC) |
257 |
1,000 |
0.00% |
|
|
| 32 |
BANK OF AMERICA CORP /DE/ |
131 |
0 |
0.00% |
|
|
