| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Clarus Ventures, LLC | 2,579,062 | 51,762,000 | 25.26% | ||
| 2 | Invesco Ltd. | 1,383,448 | 27,487,000 | 13.42% | ||
| 3 | PRICE T ROWE ASSOCIATES INC /MD/ | 855,300 | 17,166,000 | 8.38% | ||
| 4 | Redmile Group, LLC | 624,869 | 12,541,000 | 6.12% | ||
| 5 | LANSDOWNE PARTNERS LIMITED PARTNERSHIP | 522,354 | 10,484,000 | 5.12% | ||
| 6 | Fosun International Ltd | 467,551 | 9,384,000 | 4.58% | ||
| 7 | Alyeska Investment Group, L.P. | 330,433 | 6,632,000 | 3.24% | ||
| 8 | BLACKROCK ADVISORS LLC | 304,508 | 6,111,000 | 2.98% | ||
| 9 | NEXT CENTURY GROWTH INVESTORS LLC | 300,965 | 6,040,000 | 2.95% | ||
| 10 | OppenheimerFunds, Inc. | 264,227 | 5,303,000 | 2.59% | ||
| 11 | WELLS FARGO & COMPANY/MN | 245,937 | 4,936,000 | 2.41% | ||
| 12 | FMR LLC | 230,000 | 4,616,000 | 2.25% | ||
| 13 | Cortina Asset Management, LLC | 217,177 | 4,359,000 | 2.13% | ||
| 14 | WALL STREET ASSOCIATES | 208,600 | 4,187,000 | 2.04% | ||
| 15 | DRIEHAUS CAPITAL MANAGEMENT LLC | 184,917 | 3,711,000 | 1.81% | ||
| 16 | BlackRock Fund Advisors | 177,067 | 3,554,000 | 1.73% | ||
| 17 | First Light Asset Management, LLC | 175,347 | 3,519,000 | 1.72% | ||
| 18 | BlackRock Group LTD | 174,056 | 3,493,000 | 1.70% | ||
| 19 | Tamarack Capital Management, LLC | 167,625 | 3,364,000 | 1.64% | ||
| 20 | Nicholas Investment Partners, LP | 103,615 | 2,079,000 | 1.01% | ||
| 21 | DEUTSCHE BANK AG\ | 92,315 | 1,852,000 | 0.90% | ||
| 22 | AXA S.A. | 77,104 | 1,547,000 | 0.76% | ||
| 23 | STATE STREET CORP | 74,127 | 1,488,000 | 0.73% | ||
| 24 | KORNITZER CAPITAL MANAGEMENT INC /KS | 72,188 | 1,449,000 | 0.71% | ||
| 25 | NORTHERN TRUST CORP | 65,294 | 1,311,000 | 0.64% | ||
| 26 | BlackRock Investment Management, LLC | 62,606 | 1,257,000 | 0.61% | ||
| 27 | BlackRock Institutional Trust Company, N.A. | 61,475 | 1,234,000 | 0.60% | ||
| 28 | Bank of New York Mellon Corp | 35,306 | 709,000 | 0.35% | ||
| 29 | AMERIPRISE FINANCIAL INC | 28,300 | 568,000 | 0.28% | ||
| 30 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 27,857 | 530,000 | 0.26% | ||
| 31 | Waterstone Capital Management, L.P. | 25,000 | 502,000 | 0.25% | ||
| 32 | FRIESS ASSOCIATES LLC | 22,400 | 450,000 | 0.22% | ||
| 33 | TIAA CREF INVESTMENT MANAGEMENT LLC | 15,980 | 321,000 | 0.16% | ||
| 34 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 11,200 | 225,000 | 0.11% | ||
| 35 | VANGUARD GROUP INC | 10,114 | 203,000 | 0.10% | ||
| 36 | TEACHERS ADVISORS, LLC | 6,100 | 122,000 | 0.06% | ||
| 37 | Nationwide Fund Advisors | 4,767 | 96,000 | 0.05% | ||
| 38 | AMERICAN INTERNATIONAL GROUP, INC. | 4,192 | 84,133 | 0.04% | ||
| 39 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 3,060 | 61,000 | 0.03% | ||
| 40 | STRS OHIO | 2,500 | 50,000 | 0.02% | ||
| 41 | BARCLAYS PLC | 2,061 | 41,000 | 0.02% | ||
| 42 | PANAGORA ASSET MANAGEMENT INC | 1,065 | 21,000 | 0.01% | ||
| 43 | CITIGROUP INC | 951 | 19,000 | 0.01% | ||
| 44 | MANAGED ACCOUNT ADVISORS LLC | 856 | 17,000 | 0.01% | ||
| 45 | UBS AG | 100 | 2,000 | 0.00% | ||
| 46 | MORGAN STANLEY | 36 | 1,000 | 0.00% | ||
| 47 | Tower Research Capital LLC (TRC) | 0 | 0 | 0.00% | ||
| 48 | BANK OF AMERICA CORP /DE/ | 12 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
