| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Clarus Ventures, LLC | 2,730,765 | 23,266,000 | 18.76% | ||
| 2 | Abingworth LLP | 2,199,012 | 18,692,000 | 15.07% | ||
| 3 | Park West Asset Management LLC | 1,618,676 | 13,791,000 | 11.12% | ||
| 4 | CANNELL CAPITAL LLC | 1,113,571 | 9,488,000 | 7.65% | ||
| 5 | GOLDMAN SACHS GROUP INC | 783,928 | 6,679,000 | 5.38% | ||
| 6 | ORBIMED ADVISORS LLC | 742,574 | 6,327,000 | 5.10% | ||
| 7 | GILDER GAGNON HOWE & CO LLC | 697,383 | 5,942,000 | 4.79% | ||
| 8 | AMERIPRISE FINANCIAL INC | 559,414 | 4,766,000 | 3.84% | ||
| 9 | PURA VIDA INVESTMENTS, LLC | 500,000 | 4,260,000 | 3.43% | ||
| 10 | Jefferies Group LLC | 497,100 | 4,235,000 | 3.41% | Put | |
| 11 | CLOVERDALE CAPITAL MANAGEMENT, LLC | 351,039 | 2,991,000 | 2.41% | ||
| 12 | SCHONFELD STRATEGIC ADVISORS LLC | 335,000 | 2,854,000 | 2.30% | ||
| 13 | VANGUARD GROUP INC | 285,687 | 2,434,000 | 1.96% | ||
| 14 | Atika Capital Management LLC | 210,000 | 1,789,000 | 1.44% | ||
| 15 | MILLENNIUM MANAGEMENT LLC | 176,623 | 1,505,000 | 1.21% | ||
| 16 | SCHRODER INVESTMENT MANAGEMENT GROUP | 169,741 | 1,446,000 | 1.17% | ||
| 17 | BAMCO INC /NY/ | 168,500 | 1,436,000 | 1.16% | ||
| 18 | Jefferies Group LLC | 160,000 | 1,363,000 | 1.10% | ||
| 19 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 155,200 | 1,322,000 | 1.07% | ||
| 20 | PRELUDE CAPITAL MANAGEMENT, LLC | 147,813 | 1,259,000 | 1.01% | ||
| 21 | 22NW, LP | 132,400 | 1,128,000 | 0.91% | ||
| 22 | BlackRock Institutional Trust Company, N.A. | 109,324 | 931,000 | 0.75% | ||
| 23 | Parallax Volatility Advisers, L.P. | 100,000 | 852,000 | 0.69% | Put | |
| 24 | GEODE CAPITAL MANAGEMENT, LLC | 81,874 | 697,000 | 0.56% | ||
| 25 | SABBY MANAGEMENT, LLC | 70,973 | 605,000 | 0.49% | ||
| 26 | Birchview Capital, LP | 63,300 | 539,000 | 0.43% | ||
| 27 | Bank of New York Mellon Corp | 51,510 | 439,000 | 0.35% | ||
| 28 | Parallax Volatility Advisers, L.P. | 45,438 | 387,000 | 0.31% | ||
| 29 | BlackRock Fund Advisors | 40,785 | 347,000 | 0.28% | ||
| 30 | BLAIR WILLIAM & CO/IL | 30,164 | 257,000 | 0.21% | ||
| 31 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 25,747 | 219,000 | 0.18% | ||
| 32 | RAYMOND JAMES & ASSOCIATES | 25,500 | 217,000 | 0.17% | ||
| 33 | MORGAN STANLEY | 23,353 | 198,000 | 0.16% | ||
| 34 | FIRST NEW YORK SECURITIES LLC /NY | 22,143 | 188,658 | 0.15% | ||
| 35 | FNY PARTNERS FUND LP | 21,143 | 180,000 | 0.15% | ||
| 36 | NORTHERN TRUST CORP | 20,971 | 179,000 | 0.14% | ||
| 37 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 16,300 | 139,000 | 0.11% | Put | |
| 38 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 14,345 | 122,000 | 0.10% | ||
| 39 | TIAA CREF INVESTMENT MANAGEMENT LLC | 13,460 | 115,000 | 0.09% | ||
| 40 | WELLS FARGO & COMPANY/MN | 12,831 | 109,000 | 0.09% | ||
| 41 | Brandywine Global Investment Management, LLC | 9,640 | 83,000 | 0.07% | ||
| 42 | UBS Group AG | 7,215 | 61,000 | 0.05% | ||
| 43 | CITIGROUP INC | 5,990 | 51,000 | 0.04% | ||
| 44 | Joel Isaacson & Co., LLC | 4,800 | 41,000 | 0.03% | ||
| 45 | ADVISOR GROUP, INC. | 3,500 | 30,000 | 0.02% | ||
| 46 | Segantii Capital Management Ltd | 2,700 | 23,000 | 0.02% | ||
| 47 | BlackRock Investment Management, LLC | 2,301 | 20,000 | 0.02% | ||
| 48 | BANK OF AMERICA CORP /DE/ | 1,300 | 11,000 | 0.01% | ||
| 49 | BANK OF MONTREAL /CAN/ | 1,000 | 8,000 | 0.01% | ||
| 50 | Allworth Financial LP | 680 | 6,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
