| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 13,129,697 | 47,661,000 | 16.98% | ||
| 2 | WELLINGTON MANAGEMENT GROUP LLP | 6,156,658 | 22,349,000 | 7.96% | ||
| 3 | Broadfin Capital, LLC | 5,598,019 | 20,321,000 | 7.24% | ||
| 4 | Palo Alto Investors LP | 5,180,101 | 18,804,000 | 6.70% | ||
| 5 | OppenheimerFunds, Inc. | 5,000,000 | 18,150,000 | 6.47% | ||
| 6 | VANGUARD GROUP INC | 4,117,277 | 14,946,000 | 5.33% | ||
| 7 | BlackRock Institutional Trust Company, N.A. | 3,313,446 | 12,028,000 | 4.29% | ||
| 8 | BlackRock Fund Advisors | 3,257,486 | 11,825,000 | 4.21% | ||
| 9 | NEA Management Company, LLC | 3,243,150 | 11,773,000 | 4.20% | ||
| 10 | DEERFIELD MANAGEMENT COMPANY, L.P. | 2,397,855 | 8,704,000 | 3.10% | ||
| 11 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,900,196 | 6,898,000 | 2.46% | ||
| 12 | MILLENNIUM MANAGEMENT LLC | 1,780,917 | 6,465,000 | 2.30% | ||
| 13 | D. E. Shaw & Co., Inc. | 1,654,492 | 6,006,000 | 2.14% | ||
| 14 | MORGAN STANLEY | 1,471,180 | 5,340,000 | 1.90% | ||
| 15 | DIMENSIONAL FUND ADVISORS LP | 1,451,074 | 5,267,000 | 1.88% | ||
| 16 | STATE STREET CORP | 1,447,992 | 5,257,000 | 1.87% | ||
| 17 | NORTHERN TRUST CORP | 1,042,827 | 3,786,000 | 1.35% | ||
| 18 | BLACKROCK ADVISORS LLC | 1,015,346 | 3,686,000 | 1.31% | ||
| 19 | SENZAR ASSET MANAGEMENT, LLC | 923,200 | 3,352,000 | 1.19% | ||
| 20 | TFS CAPITAL LLC | 739,492 | 2,684,000 | 0.96% | ||
| 21 | AQR CAPITAL MANAGEMENT LLC | 620,000 | 2,251,000 | 0.80% | ||
| 22 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 600,000 | 2,178,000 | 0.78% | ||
| 23 | Visium Asset Management, LP | 600,060 | 2,178,000 | 0.78% | ||
| 24 | BlackRock Group LTD | 576,293 | 2,092,000 | 0.75% | ||
| 25 | BAKER BROS. ADVISORS LP | 481,972 | 1,750,000 | 0.62% | ||
| 26 | Bank of New York Mellon Corp | 475,270 | 1,725,000 | 0.61% | ||
| 27 | DRIEHAUS CAPITAL MANAGEMENT LLC | 465,509 | 1,690,000 | 0.60% | ||
| 28 | GEODE CAPITAL MANAGEMENT, LLC | 437,345 | 1,587,000 | 0.57% | ||
| 29 | NORGES BANK | 422,815 | 1,535,000 | 0.55% | ||
| 30 | RENAISSANCE TECHNOLOGIES LLC | 421,254 | 1,529,000 | 0.54% | ||
| 31 | DEUTSCHE BANK AG\ | 412,106 | 1,494,000 | 0.53% | ||
| 32 | TIAA CREF INVESTMENT MANAGEMENT LLC | 393,825 | 1,430,000 | 0.51% | ||
| 33 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 370,959 | 1,347,000 | 0.48% | ||
| 34 | BlackRock Investment Management, LLC | 361,558 | 1,312,000 | 0.47% | ||
| 35 | JACOBS LEVY EQUITY MANAGEMENT, INC | 343,448 | 1,247,000 | 0.44% | ||
| 36 | ALLIANCEBERNSTEIN L.P. | 289,420 | 1,051,000 | 0.37% | ||
| 37 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 276,100 | 1,002,000 | 0.36% | ||
| 38 | TWO SIGMA INVESTMENTS, LP | 260,027 | 944,000 | 0.34% | ||
| 39 | TWO SIGMA ADVISERS, LP | 239,191 | 868,000 | 0.31% | ||
| 40 | PRICE T ROWE ASSOCIATES INC /MD/ | 217,200 | 788,000 | 0.28% | ||
| 41 | ROYCE & ASSOCIATES LP | 215,392 | 782,000 | 0.28% | ||
| 42 | COLUMBUS CIRCLE INVESTORS | 201,167 | 730,000 | 0.26% | ||
| 43 | MARSHALL WACE, LLP | 179,764 | 653,000 | 0.23% | ||
| 44 | Neuberger Berman Group LLC | 172,600 | 627,000 | 0.22% | ||
| 45 | FRANKLIN STREET ADVISORS INC /NC | 170,000 | 618,000 | 0.22% | ||
| 46 | GOLDMAN SACHS GROUP INC | 165,253 | 600,000 | 0.21% | ||
| 47 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 159,456 | 579,000 | 0.21% | ||
| 48 | Nationwide Fund Advisors | 153,520 | 557,000 | 0.20% | ||
| 49 | Weiss Multi-Strategy Advisers LLC | 150,000 | 545,000 | 0.19% | ||
| 50 | TURNER INVESTMENTS LLC | 149,490 | 543,000 | 0.19% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
