| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | JENNISON ASSOCIATES LLC | 3,201,470 | 37,585,000 | 20.27% | ||
| 2 | QVT Financial LP | 2,287,583 | 26,530,000 | 14.31% | ||
| 3 | Broadfin Capital, LLC | 1,675,251 | 24,885,000 | 13.42% | ||
| 4 | PERCEPTIVE ADVISORS LLC | 1,274,292 | 14,960,000 | 8.07% | ||
| 5 | Opaleye Management Inc. | 1,216,400 | 14,281,000 | 7.70% | ||
| 6 | PUTNAM INVESTMENTS LLC | 940,936 | 11,046,000 | 5.96% | ||
| 7 | Lombard Odier Asset Management (USA) Corp | 600,000 | 7,044,000 | 3.80% | ||
| 8 | DEUTSCHE BANK AG\ | 549,089 | 6,445,000 | 3.48% | ||
| 9 | BlackRock Fund Advisors | 524,343 | 6,156,000 | 3.32% | ||
| 10 | VANGUARD GROUP INC | 325,061 | 3,816,000 | 2.06% | ||
| 11 | ASCEND CAPITAL, LLC | 307,293 | 3,608,000 | 1.95% | ||
| 12 | Visium Asset Management, LP | 305,500 | 3,587,000 | 1.93% | ||
| 13 | LionEye Capital Management LLC | 303,500 | 3,563,000 | 1.92% | ||
| 14 | STATE STREET CORP | 258,390 | 3,035,000 | 1.64% | ||
| 15 | BlackRock Institutional Trust Company, N.A. | 222,339 | 2,610,000 | 1.41% | ||
| 16 | NORTHERN TRUST CORP | 185,359 | 2,176,000 | 1.17% | ||
| 17 | TIAA CREF INVESTMENT MANAGEMENT LLC | 158,259 | 1,858,000 | 1.00% | ||
| 18 | SENZAR ASSET MANAGEMENT, LLC | 158,100 | 1,856,000 | 1.00% | ||
| 19 | Amici Capital, LLC | 100,000 | 1,174,000 | 0.63% | ||
| 20 | EverPoint Asset Management, LLC | 100,000 | 1,174,000 | 0.63% | ||
| 21 | Bank of New York Mellon Corp | 80,115 | 941,000 | 0.51% | ||
| 22 | BlackRock Investment Management, LLC | 61,621 | 723,000 | 0.39% | ||
| 23 | ClariVest Asset Management LLC | 59,531 | 698,000 | 0.38% | ||
| 24 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 38,800 | 456,000 | 0.25% | ||
| 25 | Spot Trading L.L.C | 38,400 | 451,000 | 0.24% | Call | |
| 26 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 33,028 | 388,000 | 0.21% | ||
| 27 | GEODE CAPITAL MANAGEMENT, LLC | 33,095 | 388,000 | 0.21% | ||
| 28 | TEACHERS ADVISORS, LLC | 28,618 | 336,000 | 0.18% | ||
| 29 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 25,000 | 294,000 | 0.16% | ||
| 30 | GROUP ONE TRADING LLC | 21,220 | 249,000 | 0.13% | ||
| 31 | METROPOLITAN LIFE INSURANCE CO/NY | 20,202 | 237,000 | 0.13% | ||
| 32 | UBS AG | 17,700 | 208,000 | 0.11% | Put | |
| 33 | RHUMBLINE ADVISERS | 17,138 | 201,000 | 0.11% | ||
| 34 | CREDIT SUISSE AG/ | 16,632 | 195,000 | 0.11% | ||
| 35 | Nationwide Fund Advisors | 16,385 | 192,000 | 0.10% | ||
| 36 | CITADEL ADVISORS LLC | 16,213 | 190,000 | 0.10% | ||
| 37 | VOYA INVESTMENT MANAGEMENT LLC | 15,292 | 180,000 | 0.10% | ||
| 38 | DSC Advisors, L.P. | 15,000 | 176,000 | 0.09% | ||
| 39 | MORGAN STANLEY | 14,809 | 174,000 | 0.09% | ||
| 40 | ALLIANCEBERNSTEIN L.P. | 14,210 | 167,000 | 0.09% | ||
| 41 | AMERICAN INTERNATIONAL GROUP, INC. | 13,915 | 163,362 | 0.09% | ||
| 42 | D. E. Shaw & Co., Inc. | 13,800 | 162,000 | 0.09% | ||
| 43 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 13,643 | 160,000 | 0.09% | ||
| 44 | ProShare Advisors LLC | 10,366 | 122,000 | 0.07% | ||
| 45 | BANK OF AMERICA CORP /DE/ | 9,700 | 114,000 | 0.06% | ||
| 46 | BLACKROCK ADVISORS LLC | 8,964 | 105,000 | 0.06% | ||
| 47 | BANK OF MONTREAL /CAN/ | 6,555 | 77,000 | 0.04% | ||
| 48 | DSC Advisors, L.P. | 20,000 | 62,000 | 0.03% | Put | |
| 49 | UBS AG | 3,800 | 45,000 | 0.02% | Call | |
| 50 | Cubist Systematic Strategies, LLC | 2,081 | 24,000 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
