| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 4,244,037 | 17,401,000 | 26.49% | ||
| 2 | FRANKLIN RESOURCES INC | 3,025,300 | 12,404,000 | 18.88% | ||
| 3 | Polaris Venture Management Co. V, L.L.C. | 1,968,606 | 8,071,000 | 12.29% | ||
| 4 | AWM Investment Company, Inc. | 778,849 | 3,193,000 | 4.86% | ||
| 5 | NORTHPOINTE CAPITAL LLC | 756,017 | 3,100,000 | 4.72% | ||
| 6 | SPHERA FUNDS MANAGEMENT LTD. | 709,271 | 2,908,000 | 4.43% | ||
| 7 | DEERFIELD MANAGEMENT COMPANY, L.P. | 687,257 | 2,818,000 | 4.29% | ||
| 8 | VANGUARD GROUP INC | 656,515 | 2,691,000 | 4.10% | ||
| 9 | AXA S.A. | 595,157 | 2,440,000 | 3.71% | ||
| 10 | Rock Springs Capital Management LP | 480,000 | 1,968,000 | 3.00% | ||
| 11 | AlphaMark Advisors, LLC | 226,740 | 930,000 | 1.42% | ||
| 12 | Alyeska Investment Group, L.P. | 214,866 | 881,000 | 1.34% | ||
| 13 | PRINCIPAL FINANCIAL GROUP INC | 212,122 | 869,000 | 1.32% | ||
| 14 | BlackRock Institutional Trust Company, N.A. | 183,852 | 754,000 | 1.15% | ||
| 15 | MILLENNIUM MANAGEMENT LLC | 166,588 | 683,000 | 1.04% | ||
| 16 | GEODE CAPITAL MANAGEMENT, LLC | 119,352 | 489,000 | 0.74% | ||
| 17 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 89,000 | 365,000 | 0.56% | ||
| 18 | Paloma Partners Management Co | 81,492 | 334,000 | 0.51% | ||
| 19 | BlackRock Fund Advisors | 60,667 | 249,000 | 0.38% | ||
| 20 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 60,000 | 246,000 | 0.37% | ||
| 21 | CREDIT SUISSE AG/ | 57,667 | 236,000 | 0.36% | ||
| 22 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 52,022 | 213,000 | 0.32% | ||
| 23 | JACOBS LEVY EQUITY MANAGEMENT, INC | 51,397 | 211,000 | 0.32% | ||
| 24 | Squarepoint Ops LLC | 42,900 | 176,000 | 0.27% | ||
| 25 | Birchview Capital, LP | 39,000 | 160,000 | 0.24% | ||
| 26 | AMERIPRISE FINANCIAL INC | 42,000 | 156,000 | 0.24% | ||
| 27 | DIMENSIONAL FUND ADVISORS LP | 34,799 | 143,000 | 0.22% | ||
| 28 | DEUTSCHE BANK AG\ | 33,583 | 137,000 | 0.21% | ||
| 29 | TFS CAPITAL LLC | 32,554 | 133,000 | 0.20% | ||
| 30 | Connor, Clark & Lunn Investment Management Ltd. | 29,919 | 123,000 | 0.19% | ||
| 31 | GOLDMAN SACHS GROUP INC | 29,819 | 122,000 | 0.19% | ||
| 32 | Alpine Global Management, LLC | 29,169 | 120,000 | 0.18% | ||
| 33 | Bank of New York Mellon Corp | 29,227 | 120,000 | 0.18% | ||
| 34 | NORTHERN TRUST CORP | 27,873 | 114,000 | 0.17% | ||
| 35 | Virtu KCG Holdings LLC | 23,347 | 96,000 | 0.15% | ||
| 36 | MORGAN STANLEY | 22,872 | 94,000 | 0.14% | ||
| 37 | LMR Partners LLP | 22,129 | 91,000 | 0.14% | ||
| 38 | STATE STREET CORP | 21,600 | 88,000 | 0.13% | ||
| 39 | PERCEPTIVE ADVISORS LLC | 17,313 | 71,000 | 0.11% | ||
| 40 | WEDBUSH SECURITIES INC | 10,930 | 45,000 | 0.07% | ||
| 41 | BALYASNY ASSET MANAGEMENT L.P. | 10,790 | 44,000 | 0.07% | ||
| 42 | BANK OF MONTREAL /CAN/ | 10,000 | 41,000 | 0.06% | ||
| 43 | BANK OF AMERICA CORP /DE/ | 7,863 | 32,000 | 0.05% | ||
| 44 | IFP ADVISORS, INC | 7,000 | 29,000 | 0.04% | ||
| 45 | BlackRock Investment Management, LLC | 4,258 | 17,000 | 0.03% | ||
| 46 | BLACKROCK ADVISORS LLC | 3,917 | 16,000 | 0.02% | ||
| 47 | Financial Architects, Inc | 3,000 | 12,000 | 0.02% | ||
| 48 | CITIGROUP INC | 2,500 | 10,000 | 0.02% | ||
| 49 | BARCLAYS PLC | 2,109 | 9,000 | 0.01% | ||
| 50 | WOLVERINE TRADING LP /BD | 2,000 | 8,840 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
