| 1 |
FMR LLC |
4,256,230 |
21,792,000 |
27.44% |
|
|
| 2 |
FRANKLIN RESOURCES INC |
3,025,300 |
15,490,000 |
19.50% |
|
|
| 3 |
Polaris Venture Management Co. V, L.L.C. |
1,968,606 |
10,079,000 |
12.69% |
|
|
| 4 |
NORTHPOINTE CAPITAL LLC |
1,438,286 |
7,364,000 |
9.27% |
|
|
| 5 |
DEERFIELD MANAGEMENT COMPANY, L.P. |
687,257 |
3,519,000 |
4.43% |
|
|
| 6 |
VANGUARD GROUP INC |
685,985 |
3,513,000 |
4.42% |
|
|
| 7 |
SPHERA FUNDS MANAGEMENT LTD. |
609,271 |
3,119,000 |
3.93% |
|
|
| 8 |
AXA S.A. |
595,330 |
3,048,000 |
3.84% |
|
|
| 9 |
Rock Springs Capital Management LP |
480,000 |
2,458,000 |
3.09% |
|
|
| 10 |
AlphaMark Advisors, LLC |
226,822 |
1,161,000 |
1.46% |
|
SH |
| 11 |
Alyeska Investment Group, L.P. |
223,771 |
1,146,000 |
1.44% |
|
|
| 12 |
PRINCIPAL FINANCIAL GROUP INC |
210,100 |
1,076,000 |
1.35% |
|
|
| 13 |
BlackRock Institutional Trust Company, N.A. |
183,852 |
941,000 |
1.18% |
|
|
| 14 |
GEODE CAPITAL MANAGEMENT, LLC |
141,374 |
723,000 |
0.91% |
|
|
| 15 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
119,000 |
609,000 |
0.77% |
|
|
| 16 |
MILLENNIUM MANAGEMENT LLC |
101,400 |
519,000 |
0.65% |
|
|
| 17 |
BlackRock Fund Advisors |
60,495 |
310,000 |
0.39% |
|
|
| 18 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
60,000 |
307,000 |
0.39% |
|
|
| 19 |
JACOBS LEVY EQUITY MANAGEMENT, INC |
48,897 |
250,000 |
0.31% |
|
|
| 20 |
DIMENSIONAL FUND ADVISORS LP |
48,792 |
250,000 |
0.31% |
|
|
| 21 |
ELLINGTON MANAGEMENT GROUP LLC |
39,037 |
200,000 |
0.25% |
|
|
| 22 |
Birchview Capital, LP |
39,000 |
200,000 |
0.25% |
|
|
| 23 |
GOLDMAN SACHS GROUP INC |
38,412 |
197,000 |
0.25% |
|
|
| 24 |
NORTHERN TRUST CORP |
34,636 |
177,000 |
0.22% |
|
|
| 25 |
AMERIPRISE FINANCIAL INC |
23,500 |
172,000 |
0.22% |
|
|
| 26 |
STATE STREET CORP |
21,600 |
111,000 |
0.14% |
|
|
| 27 |
Connor, Clark & Lunn Investment Management Ltd. |
17,711 |
91,000 |
0.11% |
|
|
| 28 |
TFS CAPITAL LLC |
17,137 |
88,000 |
0.11% |
|
|
| 29 |
MORGAN STANLEY |
16,573 |
85,000 |
0.11% |
|
|
| 30 |
Virtu KCG Holdings LLC |
14,562 |
75,000 |
0.09% |
|
|
| 31 |
Bank of New York Mellon Corp |
13,395 |
69,000 |
0.09% |
|
|
| 32 |
WEDBUSH SECURITIES INC |
11,430 |
59,000 |
0.07% |
|
|
| 33 |
DEUTSCHE BANK AG\ |
10,556 |
53,000 |
0.07% |
|
|
| 34 |
UBS Group AG |
5,662 |
29,000 |
0.04% |
|
|
| 35 |
PRELUDE CAPITAL MANAGEMENT, LLC |
4,500 |
23,000 |
0.03% |
Put |
|
| 36 |
BlackRock Investment Management, LLC |
4,258 |
22,000 |
0.03% |
|
|
| 37 |
CITIGROUP INC |
4,000 |
20,000 |
0.03% |
|
|
| 38 |
BLACKROCK ADVISORS LLC |
3,917 |
20,000 |
0.03% |
|
|
| 39 |
Financial Architects, Inc |
3,000 |
15,000 |
0.02% |
|
|
| 40 |
Tower Research Capital LLC (TRC) |
1,714 |
9,000 |
0.01% |
|
|
| 41 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
1,462 |
7,000 |
0.01% |
|
|
| 42 |
Shamrock Asset Management LLC |
1,000 |
5,000 |
0.01% |
|
|
| 43 |
WELLS FARGO & COMPANY/MN |
1,000 |
5,000 |
0.01% |
|
|
| 44 |
SIMPLEX TRADING, LLC |
817 |
4,000 |
0.01% |
|
|
| 45 |
ROYAL BANK OF CANADA |
502 |
3,000 |
0.00% |
|
|
| 46 |
BANK OF AMERICA CORP /DE/ |
475 |
2,000 |
0.00% |
|
|
| 47 |
PNC FINANCIAL SERVICES GROUP, INC. |
300 |
2,000 |
0.00% |
|
|
| 48 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
300 |
2,000 |
0.00% |
|
|
| 49 |
NEXT Financial Group, Inc |
100 |
1,000 |
0.00% |
|
|
