| # | % | |||||
|---|---|---|---|---|---|---|
| 51 | 683 Capital Management, LLC | 588,237 | 1,906,000 | 2.21% | ||
| 52 | MORGAN STANLEY | 633,944 | 2,054,000 | 2.38% | ||
| 53 | KINGDON CAPITAL MANAGEMENT, L.L.C. | 1,150,947 | 3,729,000 | 4.32% | ||
| 54 | VANGUARD GROUP INC | 1,264,281 | 4,096,000 | 4.75% | ||
| 55 | Redmile Group, LLC | 1,419,058 | 4,598,000 | 5.33% | ||
| 56 | BlackRock Finance, Inc. | 1,658,727 | 5,375,000 | 6.23% | ||
| 57 | Polaris Venture Management Co. V, L.L.C. | 2,473,186 | 8,013,000 | 9.29% | ||
| 58 | EcoR1 Capital, LLC | 2,537,026 | 8,220,000 | 9.53% | ||
| 59 | FMR LLC | 4,346,785 | 14,084,000 | 16.33% | ||
| 60 | FRANKLIN RESOURCES INC | 6,076,879 | 19,689,000 | 22.83% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.