| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Third Security, LLC | 19,329,538 | 247,805,000 | 15.64% | ||
| 2 | BlackRock Finance, Inc. | 11,595,500 | 148,652,000 | 9.38% | ||
| 3 | IRIDIAN ASSET MANAGEMENT LLC/CT | 10,608,993 | 136,007,000 | 8.58% | ||
| 4 | VANGUARD GROUP INC | 9,595,212 | 123,010,000 | 7.76% | ||
| 5 | BB BIOTECH AG | 8,265,304 | 105,961,000 | 6.69% | ||
| 6 | First Eagle Investment Management, LLC | 7,394,315 | 94,795,000 | 5.98% | ||
| 7 | FMR LLC | 5,493,281 | 70,424,000 | 4.44% | ||
| 8 | Invesco Ltd. | 4,442,300 | 56,950,000 | 3.59% | ||
| 9 | SENZAR ASSET MANAGEMENT, LLC | 4,087,264 | 52,399,000 | 3.31% | ||
| 10 | STATE STREET CORP | 3,674,238 | 47,106,000 | 2.97% | ||
| 11 | JPMORGAN CHASE & CO | 2,677,194 | 34,322,000 | 2.17% | ||
| 12 | SNYDER CAPITAL MANAGEMENT L P | 2,528,462 | 32,415,000 | 2.05% | ||
| 13 | MSD Partners, L.P. | 2,245,000 | 28,781,000 | 1.82% | ||
| 14 | Bank of New York Mellon Corp | 1,861,571 | 23,866,000 | 1.51% | ||
| 15 | BAKER BROS. ADVISORS LP | 1,581,424 | 20,274,000 | 1.28% | ||
| 16 | NORTHERN TRUST CORP | 1,492,747 | 19,138,000 | 1.21% | ||
| 17 | PICTET ASSET MANAGEMENT LTD | 1,548,625 | 18,274,000 | 1.15% | ||
| 18 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,233,000 | 15,807,000 | 1.00% | Call | |
| 19 | GEODE CAPITAL MANAGEMENT, LLC | 1,155,799 | 14,816,000 | 0.94% | ||
| 20 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 1,011,449 | 12,968,000 | 0.82% | ||
| 21 | OppenheimerFunds, Inc. | 1,002,764 | 12,855,000 | 0.81% | ||
| 22 | Artisan Partners Limited Partnership | 998,407 | 12,800,000 | 0.81% | ||
| 23 | NORGES BANK | 995,008 | 12,756,000 | 0.81% | ||
| 24 | MILLER VALUE PARTNERS, LLC | 949,800 | 12,176,000 | 0.77% | ||
| 25 | PANAGORA ASSET MANAGEMENT INC | 879,243 | 11,272,000 | 0.71% | ||
| 26 | NEW YORK STATE COMMON RETIREMENT FUND | 750,041 | 9,616,000 | 0.61% | ||
| 27 | Fisher Asset Management, LLC | 614,021 | 7,872,000 | 0.50% | ||
| 28 | MILLENNIUM MANAGEMENT LLC | 590,259 | 7,567,000 | 0.48% | ||
| 29 | Granite Investment Partners, LLC | 565,507 | 7,250,000 | 0.46% | ||
| 30 | KENNEDY CAPITAL MANAGEMENT LLC | 546,200 | 7,002,000 | 0.44% | ||
| 31 | MORGAN STANLEY | 530,611 | 6,803,000 | 0.43% | ||
| 32 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 511,806 | 6,562,000 | 0.41% | ||
| 33 | MACQUARIE GROUP LTD | 500,000 | 6,410,000 | 0.40% | ||
| 34 | First Light Asset Management, LLC | 416,579 | 5,341,000 | 0.34% | ||
| 35 | GOLDMAN SACHS GROUP INC | 407,884 | 5,229,000 | 0.33% | ||
| 36 | TWO SIGMA INVESTMENTS, LP | 391,412 | 5,018,000 | 0.32% | ||
| 37 | DEUTSCHE BANK AG\ | 377,551 | 4,836,000 | 0.31% | ||
| 38 | ORBIMED ADVISORS LLC | 350,000 | 4,487,000 | 0.28% | ||
| 39 | WELLS FARGO & COMPANY/MN | 347,168 | 4,451,000 | 0.28% | ||
| 40 | SEI INVESTMENTS CO | 335,025 | 4,295,000 | 0.27% | ||
| 41 | FRED ALGER MANAGEMENT, LLC | 331,394 | 4,248,000 | 0.27% | ||
| 42 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 325,000 | 4,167,000 | 0.26% | ||
| 43 | CHICAGO EQUITY PARTNERS LLC | 315,440 | 4,044,000 | 0.26% | ||
| 44 | RUBRIC CAPITAL MANAGEMENT LP | 300,000 | 3,846,000 | 0.24% | ||
| 45 | TIAA CREF INVESTMENT MANAGEMENT LLC | 295,570 | 3,789,000 | 0.24% | ||
| 46 | CREDIT SUISSE AG/ | 246,513 | 3,159,000 | 0.20% | ||
| 47 | Candriam S.C.A. | 242,000 | 3,103,000 | 0.20% | ||
| 48 | CITADEL ADVISORS LLC | 236,778 | 3,036,000 | 0.19% | ||
| 49 | BELLEVUE GROUP AG | 219,000 | 2,808,000 | 0.18% | ||
| 50 | GUGGENHEIM CAPITAL LLC | 212,694 | 2,726,000 | 0.17% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
