| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Third Security, LLC | 19,305,403 | 190,737,000 | 17.05% | ||
| 2 | IRIDIAN ASSET MANAGEMENT LLC/CT | 10,739,413 | 106,105,000 | 9.49% | ||
| 3 | VANGUARD GROUP INC | 8,452,343 | 83,509,000 | 7.47% | ||
| 4 | First Eagle Investment Management, LLC | 7,687,515 | 75,953,000 | 6.79% | ||
| 5 | BB BIOTECH AG | 7,599,832 | 75,086,000 | 6.71% | ||
| 6 | FMR LLC | 6,766,382 | 66,852,000 | 5.98% | ||
| 7 | BlackRock Fund Advisors | 5,091,303 | 50,302,000 | 4.50% | ||
| 8 | STATE STREET CORP | 3,819,690 | 37,742,000 | 3.37% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 3,035,630 | 29,992,000 | 2.68% | ||
| 10 | JPMORGAN CHASE & CO | 2,747,066 | 27,142,000 | 2.43% | ||
| 11 | Invesco Ltd. | 2,337,739 | 23,097,000 | 2.07% | ||
| 12 | SNYDER CAPITAL MANAGEMENT L P | 2,144,549 | 21,188,000 | 1.89% | ||
| 13 | VOYA INVESTMENT MANAGEMENT LLC | 1,602,192 | 15,830,000 | 1.42% | ||
| 14 | Bank of New York Mellon Corp | 1,419,004 | 14,020,000 | 1.25% | ||
| 15 | BAKER BROS. ADVISORS LP | 1,391,507 | 13,748,000 | 1.23% | ||
| 16 | BLACKROCK ADVISORS LLC | 1,390,733 | 13,740,000 | 1.23% | ||
| 17 | NORTHERN TRUST CORP | 1,375,360 | 13,589,000 | 1.21% | ||
| 18 | SENZAR ASSET MANAGEMENT, LLC | 1,225,444 | 12,107,000 | 1.08% | ||
| 19 | FRANKLIN RESOURCES INC | 1,033,808 | 10,214,000 | 0.91% | ||
| 20 | NORGES BANK | 1,014,852 | 10,026,000 | 0.90% | ||
| 21 | OppenheimerFunds, Inc. | 1,000,000 | 9,880,000 | 0.88% | ||
| 22 | MSD Partners, L.P. | 965,000 | 9,534,000 | 0.85% | ||
| 23 | GEODE CAPITAL MANAGEMENT, LLC | 904,285 | 8,934,000 | 0.80% | ||
| 24 | PANAGORA ASSET MANAGEMENT INC | 856,007 | 8,457,000 | 0.76% | ||
| 25 | TEACHERS ADVISORS, LLC | 726,329 | 7,176,000 | 0.64% | ||
| 26 | EverPoint Asset Management, LLC | 700,000 | 6,916,000 | 0.62% | Put | |
| 27 | KENNEDY CAPITAL MANAGEMENT LLC | 699,729 | 6,913,000 | 0.62% | ||
| 28 | Fisher Asset Management, LLC | 662,811 | 6,549,000 | 0.59% | ||
| 29 | MORGAN STANLEY | 612,786 | 6,055,000 | 0.54% | ||
| 30 | Point72 Asset Management, L.P. | 582,400 | 5,754,000 | 0.51% | Put | |
| 31 | BlackRock Group LTD | 582,094 | 5,751,000 | 0.51% | ||
| 32 | AMERIPRISE FINANCIAL INC | 535,003 | 5,286,000 | 0.47% | ||
| 33 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 505,000 | 4,989,000 | 0.45% | Call | |
| 34 | NEW YORK STATE COMMON RETIREMENT FUND | 488,940 | 4,831,000 | 0.43% | ||
| 35 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 470,492 | 4,649,000 | 0.42% | ||
| 36 | MACQUARIE GROUP LTD | 460,000 | 4,545,000 | 0.41% | ||
| 37 | BlackRock Investment Management, LLC | 459,695 | 4,542,000 | 0.41% | ||
| 38 | MILLENNIUM MANAGEMENT LLC | 384,099 | 3,795,000 | 0.34% | ||
| 39 | FRED ALGER MANAGEMENT, LLC | 368,566 | 3,641,000 | 0.33% | ||
| 40 | Lombard Odier Asset Management (Switzerland) SA | 360,000 | 3,557,000 | 0.32% | ||
| 41 | CITIGROUP INC | 351,068 | 3,468,000 | 0.31% | ||
| 42 | Candriam S.C.A. | 340,000 | 3,359,000 | 0.30% | ||
| 43 | BELLEVUE GROUP AG | 318,000 | 3,142,000 | 0.28% | ||
| 44 | TIAA CREF INVESTMENT MANAGEMENT LLC | 309,821 | 3,061,000 | 0.27% | ||
| 45 | SEI INVESTMENTS CO | 307,120 | 3,034,000 | 0.27% | ||
| 46 | DEUTSCHE BANK AG\ | 304,341 | 3,005,000 | 0.27% | ||
| 47 | J. Goldman & Co LP | 269,176 | 2,659,000 | 0.24% | ||
| 48 | CITADEL ADVISORS LLC | 252,952 | 2,499,000 | 0.22% | ||
| 49 | WELLS FARGO & COMPANY/MN | 247,907 | 2,449,000 | 0.22% | ||
| 50 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 224,838 | 2,221,000 | 0.20% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
