| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 4,069,020 | 12,939,000 | 29.72% | ||
| 2 | BlackRock Fund Advisors | 729,293 | 2,319,000 | 5.33% | ||
| 3 | VANGUARD GROUP INC | 713,969 | 2,271,000 | 5.22% | ||
| 4 | Foresite Capital Management II, LLC | 663,780 | 2,111,000 | 4.85% | ||
| 5 | 683 Capital Management, LLC | 600,000 | 1,908,000 | 4.38% | ||
| 6 | ROYCE & ASSOCIATES LP | 504,075 | 1,603,000 | 3.68% | ||
| 7 | BlackRock Institutional Trust Company, N.A. | 501,227 | 1,594,000 | 3.66% | ||
| 8 | Artal Group S.A. | 500,000 | 1,590,000 | 3.65% | ||
| 9 | FORESITE CAPITAL MANAGEMENT III, LLC | 469,404 | 1,493,000 | 3.43% | ||
| 10 | D. E. Shaw & Co., Inc. | 452,432 | 1,439,000 | 3.31% | ||
| 11 | MILLENNIUM MANAGEMENT LLC | 363,377 | 1,156,000 | 2.66% | ||
| 12 | STATE STREET CORP | 352,963 | 1,122,000 | 2.58% | ||
| 13 | Spark Investment Management LLC | 352,600 | 1,121,000 | 2.58% | ||
| 14 | SABBY MANAGEMENT, LLC | 310,000 | 986,000 | 2.27% | ||
| 15 | DIMENSIONAL FUND ADVISORS LP | 306,462 | 975,000 | 2.24% | ||
| 16 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 270,651 | 861,000 | 1.98% | ||
| 17 | NORTHERN TRUST CORP | 228,385 | 726,000 | 1.67% | ||
| 18 | PANAGORA ASSET MANAGEMENT INC | 169,660 | 540,000 | 1.24% | ||
| 19 | GEODE CAPITAL MANAGEMENT, LLC | 143,892 | 457,000 | 1.05% | ||
| 20 | FT OPTIONS LLC | 131,930 | 420,000 | 0.96% | ||
| 21 | FEDERATED HERMES, INC. | 129,661 | 412,000 | 0.95% | ||
| 22 | TIAA CREF INVESTMENT MANAGEMENT LLC | 120,528 | 383,000 | 0.88% | ||
| 23 | Connor, Clark & Lunn Investment Management Ltd. | 113,700 | 362,000 | 0.83% | ||
| 24 | Paloma Partners Management Co | 110,722 | 352,000 | 0.81% | ||
| 25 | Candriam S.C.A. | 108,000 | 343,000 | 0.79% | ||
| 26 | MORGAN STANLEY | 102,771 | 327,000 | 0.75% | ||
| 27 | Bank of New York Mellon Corp | 98,405 | 313,000 | 0.72% | ||
| 28 | BlackRock Investment Management, LLC | 89,134 | 283,000 | 0.65% | ||
| 29 | PRICE T ROWE ASSOCIATES INC /MD/ | 70,915 | 226,000 | 0.52% | ||
| 30 | DEUTSCHE BANK AG\ | 53,945 | 170,000 | 0.39% | ||
| 31 | JPMORGAN CHASE & CO | 47,779 | 152,000 | 0.35% | ||
| 32 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 47,625 | 151,000 | 0.35% | ||
| 33 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 44,572 | 142,000 | 0.33% | ||
| 34 | ROYAL BANK OF CANADA | 44,328 | 141,000 | 0.32% | ||
| 35 | AQR CAPITAL MANAGEMENT LLC | 42,946 | 137,000 | 0.31% | ||
| 36 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 42,275 | 134,000 | 0.31% | ||
| 37 | CREDIT SUISSE AG/ | 38,459 | 122,000 | 0.28% | ||
| 38 | TEACHERS ADVISORS, LLC | 32,077 | 102,000 | 0.23% | ||
| 39 | GOLDMAN SACHS GROUP INC | 31,080 | 99,000 | 0.23% | ||
| 40 | JACOBS LEVY EQUITY MANAGEMENT, INC | 29,200 | 93,000 | 0.21% | ||
| 41 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 28,300 | 90,000 | 0.21% | Call | |
| 42 | CITIGROUP INC | 23,902 | 76,000 | 0.17% | ||
| 43 | AJO, LP | 23,979 | 76,000 | 0.17% | ||
| 44 | A.R.T. Advisors, LLC | 23,700 | 75,000 | 0.17% | ||
| 45 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 23,600 | 75,000 | 0.17% | Put | |
| 46 | RHUMBLINE ADVISERS | 21,283 | 68,000 | 0.16% | ||
| 47 | WADE G W & INC | 20,000 | 64,000 | 0.15% | ||
| 48 | TFS CAPITAL LLC | 19,852 | 63,000 | 0.14% | ||
| 49 | GROUP ONE TRADING LLC | 18,718 | 60,000 | 0.14% | ||
| 50 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 18,505 | 59,000 | 0.14% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
