| # | % | |||||
|---|---|---|---|---|---|---|
| 51 | Rock Springs Capital Management LP | 231,500 | 21,675,000 | 0.44% | ||
| 52 | C WorldWide Group Holding A/S | 223,560 | 20,932,000 | 0.42% | ||
| 53 | JANUS HENDERSON GROUP PLC | 217,205 | 20,337,000 | 0.41% | ||
| 54 | EMERALD MUTUAL FUND ADVISERS TRUST | 205,649 | 19,255,000 | 0.39% | ||
| 55 | VOYA INVESTMENT MANAGEMENT LLC | 194,969 | 18,255,000 | 0.37% | ||
| 56 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 189,627 | 17,755,000 | 0.36% | ||
| 57 | ARROWGRASS CAPITAL PARTNERS (US) LP | 174,569 | 16,345,000 | 0.33% | ||
| 58 | PICTET ASSET MANAGEMENT LTD | 315,663 | 16,307,000 | 0.33% | ||
| 59 | Candriam S.C.A. | 169,000 | 15,824,000 | 0.32% | ||
| 60 | BALYASNY ASSET MANAGEMENT L.P. | 165,000 | 15,449,000 | 0.31% | Call | |
| 61 | BANK OF AMERICA CORP /DE/ | 160,800 | 15,056,000 | 0.30% | Call | |
| 62 | CREDIT SUISSE AG/ | 160,653 | 15,042,000 | 0.30% | ||
| 63 | BANK OF AMERICA CORP /DE/ | 154,800 | 14,494,000 | 0.29% | Put | |
| 64 | Redmile Group, LLC | 152,000 | 14,232,000 | 0.29% | Call | |
| 65 | Tekla Capital Management LLC | 150,800 | 14,119,000 | 0.29% | ||
| 66 | MILLENNIUM MANAGEMENT LLC | 147,217 | 13,784,000 | 0.28% | ||
| 67 | BARCLAYS PLC | 146,400 | 13,708,000 | 0.28% | Put | |
| 68 | WOLVERINE TRADING LP /BD | 149,000 | 13,708,000 | 0.28% | Put | |
| 69 | Avoro Capital Advisors LLC | 140,700 | 13,174,000 | 0.27% | ||
| 70 | Allianz Asset Management GmbH | 141,993 | 13,162,000 | 0.27% | ||
| 71 | Bain Capital Public Equity Management, LLC | 140,558 | 13,160,000 | 0.27% | ||
| 72 | Nokota Management, LP | 138,700 | 12,986,000 | 0.26% | ||
| 73 | MORGAN STANLEY | 130,409 | 12,211,000 | 0.25% | ||
| 74 | CASDIN CAPITAL, LLC | 130,000 | 12,172,000 | 0.25% | ||
| 75 | RICE HALL JAMES & ASSOCIATES, LLC | 126,413 | 11,836,000 | 0.24% | ||
| 76 | PEREGRINE CAPITAL MANAGEMENT INC /MN/ | 126,170 | 11,813,000 | 0.24% | ||
| 77 | HBK INVESTMENTS L P | 125,406 | 11,742,000 | 0.24% | ||
| 78 | OppenheimerFunds, Inc. | 123,264 | 11,541,000 | 0.23% | ||
| 79 | COLUMBUS CIRCLE INVESTORS | 122,532 | 11,473,000 | 0.23% | ||
| 80 | MARSHALL WACE NORTH AMERICA, L.P. | 121,954 | 11,464,000 | 0.23% | ||
| 81 | Nationwide Fund Advisors | 117,428 | 10,995,000 | 0.22% | ||
| 82 | BARCLAYS PLC | 115,142 | 10,781,000 | 0.22% | ||
| 83 | SCHONFELD STRATEGIC ADVISORS LLC | 110,657 | 10,360,000 | 0.21% | ||
| 84 | Versant Venture Management, LLC | 101,855 | 9,542,795 | 0.19% | ||
| 85 | FIRST MANHATTAN CO. LLC. | 101,800 | 9,531,000 | 0.19% | ||
| 86 | FOLGER HILL ASSET MANAGEMENT LP | 101,002 | 9,457,000 | 0.19% | ||
| 87 | D. E. Shaw & Co., Inc. | 100,000 | 9,363,000 | 0.19% | Call | |
| 88 | BLUE JAY CAPITAL MANAGEMENT, LLC | 99,101 | 9,279,000 | 0.19% | ||
| 89 | GOLDMAN SACHS GROUP INC | 95,500 | 8,942,000 | 0.18% | Call | |
| 90 | SPHERA FUNDS MANAGEMENT LTD. | 93,000 | 8,708,000 | 0.18% | ||
| 91 | FRONTIER CAPITAL MANAGEMENT CO LLC | 92,159 | 8,629,000 | 0.17% | ||
| 92 | CRAWFORD LAKE CAPITAL MANAGEMENT, LLC | 91,191 | 8,538,000 | 0.17% | ||
| 93 | BOSTON ADVISORS LLC | 88,985 | 8,332,000 | 0.17% | ||
| 94 | GROUP ONE TRADING LLC | 85,811 | 8,034,000 | 0.16% | ||
| 95 | CITADEL ADVISORS LLC | 82,400 | 7,715,000 | 0.16% | Call | |
| 96 | Quantitative Investment Management, LLC | 77,800 | 7,284,000 | 0.15% | ||
| 97 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 76,735 | 7,185,000 | 0.15% | ||
| 98 | Swiss National Bank | 76,450 | 7,158,000 | 0.14% | ||
| 99 | Iguana Healthcare Management, LLC | 75,000 | 7,022,000 | 0.14% | ||
| 100 | KINGDON CAPITAL MANAGEMENT, L.L.C. | 74,881 | 7,011,000 | 0.14% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
