| 1 |
FMR LLC |
2,385,597 |
13,693,000 |
25.43% |
|
|
| 2 |
Versant Venture Management, LLC |
1,281,152 |
7,353,812 |
13.66% |
|
|
| 3 |
MAZAMA CAPITAL MANAGEMENT INC |
1,238,936 |
7,111,000 |
13.21% |
|
|
| 4 |
WELLCOME TRUST LTD (THE) as trustee of the WELLCOME TRUST |
1,125,616 |
6,461,000 |
12.00% |
|
|
| 5 |
Murphy Michael R |
849,648 |
4,877,000 |
9.06% |
|
|
| 6 |
AXA S.A. |
542,733 |
3,115,000 |
5.79% |
|
|
| 7 |
VANGUARD GROUP INC |
288,821 |
1,658,000 |
3.08% |
|
|
| 8 |
MILLENNIUM MANAGEMENT LLC |
268,590 |
1,542,000 |
2.86% |
|
|
| 9 |
Point72 Asset Management, L.P. |
243,490 |
1,398,000 |
2.60% |
|
|
| 10 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
137,950 |
792,000 |
1.47% |
|
|
| 11 |
BlackRock Institutional Trust Company, N.A. |
131,538 |
755,000 |
1.40% |
|
|
| 12 |
PUTNAM INVESTMENTS LLC |
123,527 |
709,000 |
1.32% |
|
|
| 13 |
CQS Cayman LP |
100,850 |
579,000 |
1.08% |
|
|
| 14 |
BAKER BROS. ADVISORS LP |
100,000 |
574,000 |
1.07% |
|
|
| 15 |
Spark Investment Management LLC |
87,300 |
501,000 |
0.93% |
|
|
| 16 |
JACOBS LEVY EQUITY MANAGEMENT, INC |
75,142 |
431,000 |
0.80% |
|
|
| 17 |
GABELLI FUNDS LLC |
53,000 |
304,000 |
0.56% |
|
|
| 18 |
BlackRock Fund Advisors |
46,357 |
266,000 |
0.49% |
|
|
| 19 |
GEODE CAPITAL MANAGEMENT, LLC |
46,241 |
265,000 |
0.49% |
|
|
| 20 |
BlackRock Group LTD |
38,834 |
223,000 |
0.41% |
|
|
| 21 |
COOKSON PEIRCE & CO INC |
38,315 |
220,000 |
0.41% |
|
SH |
| 22 |
RENAISSANCE TECHNOLOGIES LLC |
23,500 |
135,000 |
0.25% |
|
|
| 23 |
Bank of New York Mellon Corp |
21,450 |
123,000 |
0.23% |
|
|
| 24 |
Ballentine Partners, LLC |
19,823 |
114,000 |
0.21% |
|
|
| 25 |
GOLDMAN SACHS GROUP INC |
19,335 |
111,000 |
0.21% |
|
|
| 26 |
OXFORD ASSET MANAGEMENT LLP |
14,347 |
85,000 |
0.16% |
|
|
| 27 |
ICONIQ Capital, LLC |
14,296 |
82,000 |
0.15% |
|
|
| 28 |
NORTHERN TRUST CORP |
12,445 |
71,000 |
0.13% |
|
|
| 29 |
MORGAN STANLEY |
10,247 |
59,000 |
0.11% |
|
|
| 30 |
ALAMBIC INVESTMENT MANAGEMENT, L.P. |
10,100 |
58,000 |
0.11% |
|
|
| 31 |
BANK OF AMERICA CORP /DE/ |
7,935 |
46,000 |
0.09% |
|
|
| 32 |
CORNERSTONE CAPITAL MANAGEMENT HOLDINGS LLC. |
7,300 |
42,000 |
0.08% |
|
|
| 33 |
RUSSELL FRANK CO/ |
3,500 |
21,000 |
0.04% |
|
|
| 34 |
UBS Group AG |
3,385 |
20,000 |
0.04% |
|
|
| 35 |
BlackRock Investment Management, LLC |
3,196 |
18,000 |
0.03% |
|
|
| 36 |
Tower Research Capital LLC (TRC) |
2,674 |
15,000 |
0.03% |
|
|
| 37 |
GIERL AUGUSTINE INVESTMENT MANAGEMENT INC |
1,000 |
6,000 |
0.01% |
|
|
| 38 |
ACADIAN ASSET MANAGEMENT LLC |
128 |
1,000 |
0.00% |
|
|
| 39 |
Walleye Trading LLC |
100 |
1,000 |
0.00% |
|
|
