| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | NEA Management Company, LLC | 4,715,128 | 22,585,000 | 31.41% | ||
| 2 | FMR LLC | 2,575,797 | 12,338,000 | 17.16% | ||
| 3 | EcoR1 Capital, LLC | 1,679,707 | 8,046,000 | 11.19% | ||
| 4 | SPHERA FUNDS MANAGEMENT LTD. | 1,300,313 | 6,228,000 | 8.66% | ||
| 5 | Versant Venture Management, LLC | 1,281,152 | 6,136,718 | 8.53% | ||
| 6 | Point72 Asset Management, L.P. | 890,000 | 4,263,000 | 5.93% | ||
| 7 | VANGUARD GROUP INC | 439,478 | 2,105,000 | 2.93% | ||
| 8 | RENAISSANCE TECHNOLOGIES LLC | 295,500 | 1,415,000 | 1.97% | ||
| 9 | AXA S.A. | 267,844 | 1,283,000 | 1.78% | ||
| 10 | DEUTSCHE BANK AG\ | 169,614 | 811,000 | 1.13% | ||
| 11 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 156,185 | 748,000 | 1.04% | ||
| 12 | Polar Capital LLP | 145,000 | 695,000 | 0.97% | ||
| 13 | Spark Investment Management LLC | 143,865 | 689,000 | 0.96% | ||
| 14 | PUTNAM INVESTMENTS LLC | 123,527 | 592,000 | 0.82% | ||
| 15 | GEODE CAPITAL MANAGEMENT, LLC | 110,663 | 530,000 | 0.74% | ||
| 16 | BlackRock Institutional Trust Company, N.A. | 103,851 | 497,000 | 0.69% | ||
| 17 | BAKER BROS. ADVISORS LP | 100,000 | 479,000 | 0.67% | ||
| 18 | CQS Cayman LP | 90,850 | 435,000 | 0.61% | ||
| 19 | BlackRock Fund Advisors | 60,100 | 288,000 | 0.40% | ||
| 20 | GABELLI FUNDS LLC | 51,800 | 248,000 | 0.34% | ||
| 21 | MORGAN STANLEY | 43,500 | 208,000 | 0.29% | ||
| 22 | BlackRock Group LTD | 38,834 | 186,000 | 0.26% | ||
| 23 | Redmile Group, LLC | 32,300 | 155,000 | 0.22% | ||
| 24 | BANK OF AMERICA CORP /DE/ | 31,118 | 149,000 | 0.21% | ||
| 25 | ICONIQ Capital, LLC | 28,629 | 137,000 | 0.19% | ||
| 26 | GOLDMAN SACHS GROUP INC | 26,689 | 128,000 | 0.18% | ||
| 27 | MILLENNIUM MANAGEMENT LLC | 24,955 | 120,000 | 0.17% | ||
| 28 | NORTHERN TRUST CORP | 23,346 | 112,000 | 0.16% | ||
| 29 | Ballentine Partners, LLC | 19,823 | 95,000 | 0.13% | ||
| 30 | Creative Planning | 15,000 | 72,000 | 0.10% | ||
| 31 | JACOBS LEVY EQUITY MANAGEMENT, INC | 15,019 | 72,000 | 0.10% | ||
| 32 | BlackRock Investment Management, LLC | 3,744 | 18,000 | 0.03% | ||
| 33 | Tower Research Capital LLC (TRC) | 1,936 | 9,000 | 0.01% | ||
| 34 | JPMORGAN CHASE & CO | 1,700 | 8,000 | 0.01% | ||
| 35 | GIERL AUGUSTINE INVESTMENT MANAGEMENT INC | 1,500 | 7,000 | 0.01% | ||
| 36 | UBS Group AG | 1,500 | 7,000 | 0.01% | ||
| 37 | SIMPLEX TRADING, LLC | 1,399 | 6,000 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
