| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | NEA Management Company, LLC | 4,715,128 | 17,870,000 | 34.65% | ||
| 2 | FMR LLC | 2,621,797 | 9,937,000 | 19.27% | ||
| 3 | EcoR1 Capital, LLC | 1,571,708 | 5,957,000 | 11.55% | ||
| 4 | Versant Venture Management, LLC | 1,281,152 | 4,855,566 | 9.42% | ||
| 5 | Point72 Asset Management, L.P. | 890,000 | 3,373,000 | 6.54% | ||
| 6 | VANGUARD GROUP INC | 358,478 | 1,358,000 | 2.63% | ||
| 7 | DAFNA Capital Management LLC | 314,341 | 1,191,000 | 2.31% | ||
| 8 | AXA S.A. | 267,844 | 1,015,000 | 1.97% | ||
| 9 | RENAISSANCE TECHNOLOGIES LLC | 170,100 | 645,000 | 1.25% | ||
| 10 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 156,185 | 592,000 | 1.15% | ||
| 11 | DEUTSCHE BANK AG\ | 132,210 | 501,000 | 0.97% | ||
| 12 | PUTNAM INVESTMENTS LLC | 123,527 | 468,000 | 0.91% | ||
| 13 | BlackRock Institutional Trust Company, N.A. | 103,851 | 394,000 | 0.76% | ||
| 14 | Polar Capital LLP | 100,000 | 379,000 | 0.73% | ||
| 15 | BAKER BROS. ADVISORS LP | 100,000 | 379,000 | 0.73% | ||
| 16 | CQS Cayman LP | 90,850 | 344,000 | 0.67% | ||
| 17 | JACOBS LEVY EQUITY MANAGEMENT, INC | 62,572 | 237,000 | 0.46% | ||
| 18 | GABELLI FUNDS LLC | 52,800 | 200,000 | 0.39% | ||
| 19 | MORGAN STANLEY | 48,782 | 184,000 | 0.36% | ||
| 20 | GEODE CAPITAL MANAGEMENT, LLC | 46,187 | 175,000 | 0.34% | ||
| 21 | BlackRock Fund Advisors | 41,882 | 159,000 | 0.31% | ||
| 22 | BlackRock Group LTD | 38,834 | 147,000 | 0.29% | ||
| 23 | EAGLE GLOBAL ADVISORS LLC | 38,749 | 147,000 | 0.29% | ||
| 24 | A.R.T. Advisors, LLC | 37,507 | 142,000 | 0.28% | ||
| 25 | BANK OF AMERICA CORP /DE/ | 32,700 | 124,000 | 0.24% | ||
| 26 | ICONIQ Capital, LLC | 28,629 | 109,000 | 0.21% | ||
| 27 | GOLDMAN SACHS GROUP INC | 25,731 | 98,000 | 0.19% | ||
| 28 | NOMURA HOLDINGS INC | 25,100 | 96,000 | 0.19% | ||
| 29 | MILLENNIUM MANAGEMENT LLC | 24,043 | 91,000 | 0.18% | ||
| 30 | Ballentine Partners, LLC | 19,823 | 75,000 | 0.15% | ||
| 31 | NORTHERN TRUST CORP | 15,300 | 58,000 | 0.11% | ||
| 32 | Spark Investment Management LLC | 15,100 | 57,000 | 0.11% | ||
| 33 | Creative Planning | 15,000 | 57,000 | 0.11% | ||
| 34 | TFS CAPITAL LLC | 13,587 | 51,000 | 0.10% | ||
| 35 | Walleye Trading LLC | 8,100 | 31,000 | 0.06% | ||
| 36 | EMERALD ACQUISITION LTD. | 7,147 | 27,000 | 0.05% | ||
| 37 | BlackRock Investment Management, LLC | 2,468 | 9,000 | 0.02% | ||
| 38 | CORNERSTONE CAPITAL MANAGEMENT HOLDINGS LLC. | 2,500 | 9,000 | 0.02% | ||
| 39 | Nationwide Fund Advisors | 2,200 | 8,000 | 0.02% | ||
| 40 | GIERL AUGUSTINE INVESTMENT MANAGEMENT INC | 1,500 | 6,000 | 0.01% | ||
| 41 | UBS Group AG | 1,500 | 6,000 | 0.01% | ||
| 42 | Tower Research Capital LLC (TRC) | 881 | 3,000 | 0.01% | ||
| 43 | ACADIAN ASSET MANAGEMENT LLC | 328 | 1,000 | 0.00% | ||
| 44 | ADVISOR GROUP, INC. | 357 | 1,000 | 0.00% | ||
| 45 | CUTLER GROUP LLC / CA | 300 | 0 | 0.00% | Call |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
