| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Essex Woodlands Management, Inc. | 4,592,047 | 77,789,000 | 23.24% | ||
| 2 | NQ HCIF GP, Ltd. | 3,096,650 | 52,457,000 | 15.67% | ||
| 3 | FRANKLIN RESOURCES INC | 2,754,139 | 46,654,000 | 13.94% | ||
| 4 | Polar Capital LLP | 1,107,272 | 18,756,000 | 5.60% | ||
| 5 | Bank of New York Mellon Corp | 1,023,422 | 17,337,000 | 5.18% | ||
| 6 | Visium Asset Management, LP | 1,000,000 | 16,940,000 | 5.06% | ||
| 7 | ArrowMark Colorado Holdings LLC | 787,923 | 13,347,000 | 3.99% | ||
| 8 | JPMORGAN CHASE & CO | 722,276 | 12,236,000 | 3.66% | ||
| 9 | ALLIANCEBERNSTEIN L.P. | 575,906 | 9,756,000 | 2.91% | ||
| 10 | BlackRock Fund Advisors | 515,592 | 8,734,000 | 2.61% | ||
| 11 | GOLDMAN SACHS GROUP INC | 402,755 | 6,823,000 | 2.04% | ||
| 12 | VANGUARD GROUP INC | 383,898 | 6,503,000 | 1.94% | ||
| 13 | WADDELL & REED FINANCIAL INC | 349,050 | 5,913,000 | 1.77% | ||
| 14 | AMERIPRISE FINANCIAL INC | 252,494 | 4,277,000 | 1.28% | ||
| 15 | Lombard Odier Asset Management (USA) Corp | 250,605 | 4,245,000 | 1.27% | ||
| 16 | WELLINGTON MANAGEMENT GROUP LLP | 160,212 | 2,714,000 | 0.81% | ||
| 17 | Rhenman & Partners Asset Management AB | 126,574 | 2,144,000 | 0.64% | ||
| 18 | JENNISON ASSOCIATES LLC | 109,125 | 1,849,000 | 0.55% | ||
| 19 | STATE STREET CORP | 103,742 | 1,756,000 | 0.52% | ||
| 20 | Jefferies Group LLC | 100,000 | 1,694,000 | 0.51% | ||
| 21 | BlackRock Institutional Trust Company, N.A. | 94,622 | 1,603,000 | 0.48% | ||
| 22 | NORTHERN TRUST CORP | 92,450 | 1,566,000 | 0.47% | ||
| 23 | LEVIN CAPITAL STRATEGIES, L.P. | 87,984 | 1,490,000 | 0.45% | ||
| 24 | MILLENNIUM MANAGEMENT LLC | 86,552 | 1,466,000 | 0.44% | ||
| 25 | Zweig-DiMenna Associates LLC | 83,000 | 1,406,000 | 0.42% | ||
| 26 | SABBY MANAGEMENT, LLC | 76,400 | 1,294,000 | 0.39% | ||
| 27 | PRINCIPAL FINANCIAL GROUP INC | 72,438 | 1,227,000 | 0.37% | ||
| 28 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 65,200 | 1,104,000 | 0.33% | ||
| 29 | GEODE CAPITAL MANAGEMENT, LLC | 64,904 | 1,099,000 | 0.33% | ||
| 30 | WALL STREET ASSOCIATES | 57,330 | 971,000 | 0.29% | ||
| 31 | CITADEL ADVISORS LLC | 49,974 | 846,000 | 0.25% | ||
| 32 | Standard Investments LLC | 47,846 | 811,000 | 0.24% | ||
| 33 | BAMCO INC /NY/ | 43,000 | 728,000 | 0.22% | ||
| 34 | COLUMBUS CIRCLE INVESTORS | 38,018 | 644,000 | 0.19% | ||
| 35 | CREDIT SUISSE AG/ | 37,408 | 633,000 | 0.19% | ||
| 36 | Robert W. Baird & Co. Inc | 32,832 | 556,000 | 0.17% | ||
| 37 | TIAA CREF INVESTMENT MANAGEMENT LLC | 29,393 | 498,000 | 0.15% | ||
| 38 | BlackRock Investment Management, LLC | 26,536 | 450,000 | 0.13% | ||
| 39 | State of New Jersey Common Pension Fund D | 26,000 | 440,000 | 0.13% | ||
| 40 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 25,165 | 427,000 | 0.13% | ||
| 41 | C Partners Holding GmbH | 24,000 | 407,000 | 0.12% | ||
| 42 | NOTTINGHAM ADVISORS, INC. | 23,018 | 390,000 | 0.12% | ||
| 43 | Nationwide Fund Advisors | 18,559 | 314,000 | 0.09% | ||
| 44 | Trexquant Investment LP | 17,800 | 301,000 | 0.09% | ||
| 45 | ProShare Advisors LLC | 17,544 | 297,000 | 0.09% | ||
| 46 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 15,940 | 270,000 | 0.08% | ||
| 47 | Swiss National Bank | 12,950 | 219,000 | 0.07% | ||
| 48 | TFS CAPITAL LLC | 11,213 | 190,000 | 0.06% | ||
| 49 | TEACHERS ADVISORS, LLC | 10,524 | 178,000 | 0.05% | ||
| 50 | CITIGROUP INC | 7,840 | 133,000 | 0.04% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
