| 1 |
Essex Woodlands Management, Inc. |
4,592,047 |
74,437,000 |
16.02% |
|
|
| 2 |
JPMORGAN CHASE & CO |
3,267,701 |
52,969,000 |
11.40% |
|
|
| 3 |
FRANKLIN RESOURCES INC |
3,107,279 |
50,369,000 |
10.84% |
|
|
| 4 |
NQ HCIF GP, Ltd. |
3,096,650 |
50,197,000 |
10.81% |
|
|
| 5 |
WELLINGTON MANAGEMENT GROUP LLP |
2,413,340 |
39,120,000 |
8.42% |
|
|
| 6 |
Bank of New York Mellon Corp |
1,923,108 |
31,175,000 |
6.71% |
|
|
| 7 |
ArrowMark Colorado Holdings LLC |
1,823,214 |
29,554,000 |
6.36% |
|
|
| 8 |
Polar Capital LLP |
1,319,871 |
21,392,000 |
4.60% |
|
|
| 9 |
BlackRock Fund Advisors |
1,317,731 |
21,360,000 |
4.60% |
|
|
| 10 |
VANGUARD GROUP INC |
811,823 |
13,160,000 |
2.83% |
|
|
| 11 |
CANADA PENSION PLAN INVESTMENT BOARD |
582,900 |
9,449,000 |
2.03% |
|
|
| 12 |
BlackRock Institutional Trust Company, N.A. |
504,521 |
8,178,000 |
1.76% |
|
|
| 13 |
GOLDMAN SACHS GROUP INC |
425,625 |
6,900,000 |
1.49% |
|
|
| 14 |
ADAGE CAPITAL PARTNERS GP, L.L.C. |
350,000 |
5,674,000 |
1.22% |
|
|
| 15 |
PointState Capital LP |
325,000 |
5,268,000 |
1.13% |
|
|
| 16 |
STATE STREET CORP |
307,738 |
4,990,000 |
1.07% |
|
|
| 17 |
WADDELL & REED FINANCIAL INC |
300,000 |
4,863,000 |
1.05% |
|
|
| 18 |
NORTHERN TRUST CORP |
251,538 |
4,078,000 |
0.88% |
|
|
| 19 |
Rhenman & Partners Asset Management AB |
210,000 |
3,404,100 |
0.73% |
|
|
| 20 |
GEODE CAPITAL MANAGEMENT, LLC |
148,113 |
2,400,000 |
0.52% |
|
|
| 21 |
MORGAN STANLEY |
116,265 |
1,884,000 |
0.41% |
|
|
| 22 |
SUFFOLK CAPITAL MANAGEMENT LLC |
91,194 |
1,478,000 |
0.32% |
|
|
| 23 |
ESSEX INVESTMENT MANAGEMENT CO LLC |
86,000 |
1,394,000 |
0.30% |
|
|
| 24 |
Granite Investment Partners, LLC |
81,369 |
1,319,000 |
0.28% |
|
|
| 25 |
PRINCIPAL FINANCIAL GROUP INC |
80,352 |
1,303,000 |
0.28% |
|
|
| 26 |
BlackRock Investment Management, LLC |
78,950 |
1,280,000 |
0.28% |
|
|
| 27 |
VIVO CAPITAL, LLC |
77,373 |
1,254,000 |
0.27% |
|
|
| 28 |
Tekla Capital Management LLC |
75,000 |
1,216,000 |
0.26% |
|
|
| 29 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
71,153 |
1,153,000 |
0.25% |
|
|
| 30 |
UNITED BANK |
65,500 |
1,062,000 |
0.23% |
|
|
| 31 |
COLUMBIA PARTNERS L.L.C. INVESTMENT MANAGEMENT |
65,313 |
1,058,000 |
0.23% |
|
|
| 32 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
59,715 |
968,000 |
0.21% |
|
|
| 33 |
UNITED SERVICES AUTOMOBILE ASSOCIATION |
55,741 |
904,000 |
0.19% |
|
|
| 34 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
43,270 |
701,000 |
0.15% |
|
|
| 35 |
ALPS ADVISORS INC |
36,313 |
589,000 |
0.13% |
|
|
| 36 |
TEACHERS ADVISORS, LLC |
32,072 |
520,000 |
0.11% |
|
|
| 37 |
Nationwide Fund Advisors |
31,556 |
512,000 |
0.11% |
|
|
| 38 |
Swiss National Bank |
30,750 |
498,000 |
0.11% |
|
|
| 39 |
ALLIANCEBERNSTEIN L.P. |
29,400 |
477,000 |
0.10% |
|
|
| 40 |
State of New Jersey Common Pension Fund D |
26,000 |
421,000 |
0.09% |
|
|
| 41 |
CREDIT SUISSE AG/ |
22,886 |
371,000 |
0.08% |
|
|
| 42 |
Lombard Odier Asset Management (USA) Corp |
21,611 |
350,000 |
0.08% |
|
|
| 43 |
HIGHBRIDGE CAPITAL MANAGEMENT LLC |
20,904 |
339,000 |
0.07% |
|
|
| 44 |
PARAMETRIC PORTFOLIO ASSOCIATES LLC |
20,837 |
338,000 |
0.07% |
|
|
| 45 |
FEDERATED HERMES, INC. |
20,000 |
324,000 |
0.07% |
|
|
| 46 |
ProShare Advisors LLC |
19,985 |
324,000 |
0.07% |
|
|
| 47 |
ROYAL BANK OF CANADA |
19,535 |
317,000 |
0.07% |
|
|
| 48 |
RHUMBLINE ADVISERS |
19,430 |
315,000 |
0.07% |
|
|
| 49 |
DEUTSCHE BANK AG\ |
19,406 |
313,000 |
0.07% |
|
|
| 50 |
NEW YORK STATE COMMON RETIREMENT FUND |
18,900 |
306,000 |
0.07% |
|
|
