| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Essex Woodlands Management, Inc. | 4,592,047 | 156,864,000 | 16.79% | ||
| 2 | FRANKLIN RESOURCES INC | 3,178,895 | 108,591,000 | 11.63% | ||
| 3 | NQ HCIF GP, Ltd. | 3,096,650 | 105,782,000 | 11.32% | ||
| 4 | JPMORGAN CHASE & CO | 2,934,142 | 100,231,000 | 10.73% | ||
| 5 | Bank of New York Mellon Corp | 2,009,567 | 68,647,000 | 7.35% | ||
| 6 | Polar Capital LLP | 1,183,631 | 40,431,000 | 4.33% | ||
| 7 | BlackRock Fund Advisors | 1,049,725 | 35,859,000 | 3.84% | ||
| 8 | VANGUARD GROUP INC | 653,010 | 22,307,000 | 2.39% | ||
| 9 | CANADA PENSION PLAN INVESTMENT BOARD | 610,300 | 20,848,000 | 2.23% | ||
| 10 | LORD, ABBETT & CO. LLC | 609,768 | 20,830,000 | 2.23% | ||
| 11 | ArrowMark Colorado Holdings LLC | 588,646 | 20,108,000 | 2.15% | ||
| 12 | WADDELL & REED FINANCIAL INC | 570,850 | 19,501,000 | 2.09% | ||
| 13 | FMR LLC | 555,600 | 18,979,000 | 2.03% | ||
| 14 | WELLINGTON MANAGEMENT GROUP LLP | 521,178 | 17,803,000 | 1.91% | ||
| 15 | BlackRock Institutional Trust Company, N.A. | 439,399 | 15,010,000 | 1.61% | ||
| 16 | STATE STREET CORP | 388,796 | 13,281,000 | 1.42% | ||
| 17 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 375,000 | 12,810,000 | 1.37% | ||
| 18 | LOOMIS SAYLES & CO L P | 358,393 | 12,242,000 | 1.31% | ||
| 19 | GOLDMAN SACHS GROUP INC | 315,826 | 10,788,000 | 1.15% | ||
| 20 | Lombard Odier Asset Management (USA) Corp | 230,211 | 7,864,000 | 0.84% | ||
| 21 | RENAISSANCE TECHNOLOGIES LLC | 215,900 | 7,375,000 | 0.79% | ||
| 22 | NORTHERN TRUST CORP | 211,966 | 7,240,000 | 0.78% | ||
| 23 | FRED ALGER MANAGEMENT, LLC | 194,816 | 6,655,000 | 0.71% | ||
| 24 | Rhenman & Partners Asset Management AB | 173,000 | 5,910,000 | 0.63% | ||
| 25 | D. E. Shaw & Co., Inc. | 159,939 | 5,464,000 | 0.58% | ||
| 26 | GEODE CAPITAL MANAGEMENT, LLC | 128,718 | 4,397,000 | 0.47% | ||
| 27 | MILLENNIUM MANAGEMENT LLC | 117,850 | 4,026,000 | 0.43% | ||
| 28 | Informed Momentum Co LLC | 102,800 | 3,512,000 | 0.38% | ||
| 29 | BAIRD FINANCIAL GROUP, INC. | 82,610 | 2,822,000 | 0.30% | ||
| 30 | PRINCIPAL FINANCIAL GROUP INC | 81,748 | 2,793,000 | 0.30% | ||
| 31 | DRIEHAUS CAPITAL MANAGEMENT LLC | 78,078 | 2,667,000 | 0.29% | ||
| 32 | UNITED BANK | 77,177 | 2,636,000 | 0.28% | ||
| 33 | ESSEX INVESTMENT MANAGEMENT CO LLC | 71,701 | 2,449,000 | 0.26% | ||
| 34 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 70,813 | 2,419,000 | 0.26% | ||
| 35 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 66,500 | 2,272,000 | 0.24% | Call | |
| 36 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 66,400 | 2,268,000 | 0.24% | Put | |
| 37 | BlackRock Investment Management, LLC | 63,776 | 2,179,000 | 0.23% | ||
| 38 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 63,467 | 2,169,000 | 0.23% | ||
| 39 | COLUMBUS CIRCLE INVESTORS | 61,295 | 2,094,000 | 0.22% | ||
| 40 | OXFORD ASSET MANAGEMENT LLP | 57,641 | 1,993,000 | 0.21% | ||
| 41 | TIAA CREF INVESTMENT MANAGEMENT LLC | 55,715 | 1,903,000 | 0.20% | ||
| 42 | TWO SIGMA INVESTMENTS, LP | 48,146 | 1,645,000 | 0.18% | ||
| 43 | SUFFOLK CAPITAL MANAGEMENT LLC | 47,958 | 1,638,000 | 0.18% | ||
| 44 | AMERIPRISE FINANCIAL INC | 41,957 | 1,433,000 | 0.15% | ||
| 45 | RUSSELL FRANK CO/ | 38,974 | 1,384,000 | 0.15% | ||
| 46 | ALPS ADVISORS INC | 36,968 | 1,263,000 | 0.14% | ||
| 47 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 33,966 | 1,160,000 | 0.12% | ||
| 48 | LEVIN CAPITAL STRATEGIES, L.P. | 32,511 | 1,110,000 | 0.12% | ||
| 49 | TFS CAPITAL LLC | 29,460 | 1,006,000 | 0.11% | ||
| 50 | TEACHERS ADVISORS, LLC | 26,140 | 893,000 | 0.10% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
