| 1 |
Essex Woodlands Management, Inc. |
4,592,047 |
95,193,000 |
22.27% |
|
|
| 2 |
FRANKLIN RESOURCES INC |
3,398,192 |
70,444,000 |
16.48% |
|
|
| 3 |
NQ HCIF GP, Ltd. |
3,096,650 |
64,194,000 |
15.02% |
|
|
| 4 |
JPMORGAN CHASE & CO |
1,224,563 |
25,385,000 |
5.94% |
|
|
| 5 |
Bank of New York Mellon Corp |
1,164,294 |
24,136,000 |
5.65% |
|
|
| 6 |
Visium Asset Management, LP |
1,115,000 |
23,114,000 |
5.41% |
|
|
| 7 |
Polar Capital LLP |
1,107,272 |
22,954,000 |
5.37% |
|
|
| 8 |
ArrowMark Colorado Holdings LLC |
833,772 |
17,284,000 |
4.04% |
|
|
| 9 |
BlackRock Fund Advisors |
541,727 |
11,230,000 |
2.63% |
|
|
| 10 |
VANGUARD GROUP INC |
417,772 |
8,661,000 |
2.03% |
|
|
| 11 |
GOLDMAN SACHS GROUP INC |
415,965 |
8,623,000 |
2.02% |
|
|
| 12 |
WADDELL & REED FINANCIAL INC |
335,350 |
6,952,000 |
1.63% |
|
|
| 13 |
Lombard Odier Asset Management (USA) Corp |
278,568 |
5,775,000 |
1.35% |
|
|
| 14 |
Rhenman & Partners Asset Management AB |
236,000 |
4,892,000 |
1.14% |
|
|
| 15 |
Ghost Tree Capital, LLC |
200,000 |
4,146,000 |
0.97% |
|
|
| 16 |
STATE STREET CORP |
111,425 |
2,308,000 |
0.54% |
|
|
| 17 |
JENNISON ASSOCIATES LLC |
109,367 |
2,267,000 |
0.53% |
|
|
| 18 |
WELLINGTON MANAGEMENT GROUP LLP |
107,762 |
2,234,000 |
0.52% |
|
|
| 19 |
NORTHERN TRUST CORP |
101,676 |
2,108,000 |
0.49% |
|
|
| 20 |
BlackRock Institutional Trust Company, N.A. |
98,731 |
2,047,000 |
0.48% |
|
|
| 21 |
LEVIN CAPITAL STRATEGIES, L.P. |
92,339 |
1,914,000 |
0.45% |
|
|
| 22 |
BALYASNY ASSET MANAGEMENT L.P. |
80,323 |
1,665,000 |
0.39% |
|
|
| 23 |
GEODE CAPITAL MANAGEMENT, LLC |
70,772 |
1,467,000 |
0.34% |
|
|
| 24 |
PRINCIPAL FINANCIAL GROUP INC |
70,640 |
1,463,000 |
0.34% |
|
|
| 25 |
RENAISSANCE TECHNOLOGIES LLC |
65,409 |
1,356,000 |
0.32% |
|
|
| 26 |
TWO SIGMA INVESTMENTS, LP |
51,673 |
1,071,000 |
0.25% |
|
|
| 27 |
Standard Investments LLC |
47,846 |
992,000 |
0.23% |
|
|
| 28 |
Trexquant Investment LP |
43,300 |
897,000 |
0.21% |
|
|
| 29 |
Green Owl Capital Management, LLC |
40,000 |
829,000 |
0.19% |
|
|
| 30 |
DEUTSCHE BANK AG\ |
39,767 |
823,000 |
0.19% |
|
|
| 31 |
Robert W. Baird & Co. Inc |
34,382 |
713,000 |
0.17% |
|
|
| 32 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
31,633 |
656,000 |
0.15% |
|
|
| 33 |
BAMCO INC /NY/ |
30,000 |
622,000 |
0.15% |
|
|
| 34 |
BlackRock Investment Management, LLC |
26,941 |
558,000 |
0.13% |
|
|
| 35 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
26,800 |
556,000 |
0.13% |
Put |
|
| 36 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
26,673 |
553,000 |
0.13% |
|
|
| 37 |
TWO SIGMA ADVISERS, LP |
26,500 |
549,000 |
0.13% |
|
|
| 38 |
State of New Jersey Common Pension Fund D |
26,000 |
539,000 |
0.13% |
|
|
| 39 |
CREDIT SUISSE AG/ |
25,494 |
529,000 |
0.12% |
|
|
| 40 |
SABBY MANAGEMENT, LLC |
23,065 |
478,000 |
0.11% |
|
|
| 41 |
ProShare Advisors LLC |
20,775 |
431,000 |
0.10% |
|
|
| 42 |
COLUMBUS CIRCLE INVESTORS |
20,424 |
423,000 |
0.10% |
|
|
| 43 |
MILLENNIUM MANAGEMENT LLC |
19,890 |
412,000 |
0.10% |
|
|
| 44 |
NOTTINGHAM ADVISORS, INC. |
18,764 |
389,000 |
0.09% |
|
|
| 45 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
16,400 |
340,000 |
0.08% |
Call |
|
| 46 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
15,940 |
330,000 |
0.08% |
|
|
| 47 |
Nationwide Fund Advisors |
15,845 |
328,000 |
0.08% |
|
|
| 48 |
Quantitative Systematic Strategies LLC |
15,850 |
311,000 |
0.07% |
|
|
| 49 |
Swiss National Bank |
12,950 |
268,000 |
0.06% |
|
|
| 50 |
TEACHERS ADVISORS, LLC |
11,995 |
249,000 |
0.06% |
|
|
