| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Essex Woodlands Management, Inc. | 4,592,047 | 95,515,000 | 17.45% | ||
| 2 | JPMORGAN CHASE & CO | 3,459,844 | 71,965,000 | 13.15% | ||
| 3 | FRANKLIN RESOURCES INC | 2,983,600 | 62,059,000 | 11.34% | ||
| 4 | WELLINGTON MANAGEMENT GROUP LLP | 2,091,807 | 43,510,000 | 7.95% | ||
| 5 | BlackRock Finance, Inc. | 2,048,054 | 42,600,000 | 7.78% | ||
| 6 | ArrowMark Colorado Holdings LLC | 1,926,862 | 40,079,000 | 7.32% | ||
| 7 | Bank of New York Mellon Corp | 1,817,798 | 37,810,000 | 6.91% | ||
| 8 | Polar Capital LLP | 1,296,371 | 26,960,000 | 4.93% | ||
| 9 | VANGUARD GROUP INC | 868,118 | 18,056,000 | 3.30% | ||
| 10 | CANADA PENSION PLAN INVESTMENT BOARD | 582,900 | 12,124,000 | 2.22% | ||
| 11 | GOLDMAN SACHS GROUP INC | 548,650 | 11,412,000 | 2.09% | ||
| 12 | STATE STREET CORP | 449,853 | 9,356,000 | 1.71% | ||
| 13 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 350,000 | 7,280,000 | 1.33% | ||
| 14 | FMR LLC | 316,900 | 6,592,000 | 1.20% | ||
| 15 | PointState Capital LP | 276,500 | 5,751,000 | 1.05% | ||
| 16 | NORTHERN TRUST CORP | 265,937 | 5,532,000 | 1.01% | ||
| 17 | WADDELL & REED FINANCIAL INC | 235,000 | 4,888,000 | 0.89% | ||
| 18 | Rhenman & Partners Asset Management AB | 210,000 | 4,368,000 | 0.80% | ||
| 19 | GEODE CAPITAL MANAGEMENT, LLC | 178,435 | 3,711,000 | 0.68% | ||
| 20 | MORGAN STANLEY | 153,670 | 3,197,000 | 0.58% | ||
| 21 | Candriam S.C.A. | 122,000 | 2,538,000 | 0.46% | ||
| 22 | ESSEX INVESTMENT MANAGEMENT CO LLC | 98,684 | 2,053,000 | 0.38% | ||
| 23 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 92,490 | 1,924,000 | 0.35% | ||
| 24 | SUFFOLK CAPITAL MANAGEMENT LLC | 83,495 | 1,737,000 | 0.32% | ||
| 25 | PRINCIPAL FINANCIAL GROUP INC | 81,351 | 1,692,000 | 0.31% | ||
| 26 | VIVO CAPITAL, LLC | 77,373 | 1,609,000 | 0.29% | ||
| 27 | TIAA CREF INVESTMENT MANAGEMENT LLC | 75,274 | 1,566,000 | 0.29% | ||
| 28 | Granite Investment Partners, LLC | 71,241 | 1,482,000 | 0.27% | ||
| 29 | WELLS FARGO & COMPANY/MN | 71,148 | 1,479,000 | 0.27% | ||
| 30 | ROTHSCHILD & CO ASSET MANAGEMENT US INC. | 56,610 | 1,177,000 | 0.22% | ||
| 31 | UNITED SERVICES AUTOMOBILE ASSOCIATION | 54,971 | 1,143,000 | 0.21% | ||
| 32 | Allianz Asset Management GmbH | 50,613 | 1,053,000 | 0.19% | ||
| 33 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 40,270 | 838,000 | 0.15% | ||
| 34 | PARADIGM ASSET MANAGEMENT CO LLC | 35,700 | 742,560 | 0.14% | ||
| 35 | VICTORY CAPITAL MANAGEMENT INC | 35,525 | 739,000 | 0.14% | ||
| 36 | ACADIAN ASSET MANAGEMENT LLC | 35,338 | 735,000 | 0.13% | ||
| 37 | TEACHERS ADVISORS, LLC | 33,698 | 701,000 | 0.13% | ||
| 38 | Swiss National Bank | 32,850 | 683,000 | 0.12% | ||
| 39 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 27,401 | 570,000 | 0.10% | ||
| 40 | Nationwide Fund Advisors | 26,430 | 550,000 | 0.10% | ||
| 41 | State of New Jersey Common Pension Fund D | 26,000 | 541,000 | 0.10% | ||
| 42 | Crestline Management, LP | 25,000 | 520,000 | 0.10% | ||
| 43 | ALPS ADVISORS INC | 24,531 | 510,000 | 0.09% | ||
| 44 | ALLIANCEBERNSTEIN L.P. | 24,000 | 499,000 | 0.09% | ||
| 45 | NEW YORK STATE COMMON RETIREMENT FUND | 23,301 | 485,000 | 0.09% | ||
| 46 | RHUMBLINE ADVISERS | 22,938 | 477,000 | 0.09% | ||
| 47 | MILLENNIUM MANAGEMENT LLC | 22,705 | 472,000 | 0.09% | ||
| 48 | AMERIPRISE FINANCIAL INC | 22,679 | 472,000 | 0.09% | ||
| 49 | ROYAL BANK OF CANADA | 20,131 | 419,000 | 0.08% | ||
| 50 | FEDERATED HERMES, INC. | 20,051 | 417,000 | 0.08% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
