| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 5,239,263 | 125,114,000 | 30.90% | ||
| 2 | BLACKROCK ADVISORS LLC | 1,133,070 | 27,057,000 | 6.68% | ||
| 3 | WASATCH ADVISORS LP | 1,002,002 | 23,928,000 | 5.91% | ||
| 4 | BlackRock Fund Advisors | 976,946 | 23,329,000 | 5.76% | ||
| 5 | Visium Asset Management, LP | 976,419 | 23,317,000 | 5.76% | ||
| 6 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 700,000 | 16,716,000 | 4.13% | ||
| 7 | Redmile Group, LLC | 668,671 | 15,968,000 | 3.94% | ||
| 8 | VANGUARD GROUP INC | 629,875 | 15,041,000 | 3.71% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 460,724 | 11,002,000 | 2.72% | ||
| 10 | FRANKLIN RESOURCES INC | 366,700 | 8,757,000 | 2.16% | ||
| 11 | WALL STREET ASSOCIATES | 365,357 | 8,725,000 | 2.15% | ||
| 12 | Sarissa Capital Management LP | 360,000 | 8,597,000 | 2.12% | ||
| 13 | MORGAN STANLEY | 334,008 | 7,977,000 | 1.97% | ||
| 14 | BlackRock Group LTD | 284,947 | 6,804,000 | 1.68% | ||
| 15 | STATE STREET CORP | 251,596 | 6,009,000 | 1.48% | ||
| 16 | CLOUGH CAPITAL PARTNERS L P | 225,000 | 5,373,000 | 1.33% | ||
| 17 | EverPoint Asset Management, LLC | 220,000 | 5,254,000 | 1.30% | ||
| 18 | NORTHERN TRUST CORP | 206,149 | 4,922,000 | 1.22% | ||
| 19 | Rhenman & Partners Asset Management AB | 183,000 | 4,370,000 | 1.08% | ||
| 20 | FRED ALGER MANAGEMENT, LLC | 164,797 | 3,935,000 | 0.97% | ||
| 21 | GEODE CAPITAL MANAGEMENT, LLC | 156,661 | 3,741,000 | 0.92% | ||
| 22 | SENZAR ASSET MANAGEMENT, LLC | 150,100 | 3,584,000 | 0.89% | ||
| 23 | SPHERA FUNDS MANAGEMENT LTD. | 150,000 | 3,582,000 | 0.88% | ||
| 24 | Tekla Capital Management LLC | 150,000 | 3,582,000 | 0.88% | ||
| 25 | BlackRock Investment Management, LLC | 126,321 | 3,017,000 | 0.75% | ||
| 26 | CITADEL ADVISORS LLC | 125,723 | 3,002,000 | 0.74% | ||
| 27 | BAKER BROS. ADVISORS LP | 104,166 | 2,487,000 | 0.61% | ||
| 28 | Bank of New York Mellon Corp | 100,780 | 2,406,000 | 0.59% | ||
| 29 | SABBY MANAGEMENT, LLC | 100,000 | 2,388,000 | 0.59% | ||
| 30 | BlackRock Finance, Inc. | 97,314 | 2,324,000 | 0.57% | ||
| 31 | Point72 Asset Management, L.P. | 89,823 | 2,145,000 | 0.53% | ||
| 32 | Weiss Multi-Strategy Advisers LLC | 80,000 | 1,910,000 | 0.47% | ||
| 33 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 64,516 | 1,541,000 | 0.38% | ||
| 34 | TIAA CREF INVESTMENT MANAGEMENT LLC | 64,489 | 1,540,000 | 0.38% | ||
| 35 | MONASHEE INVESTMENT MANAGEMENT LLC | 63,978 | 1,528,000 | 0.38% | ||
| 36 | CREDIT SUISSE AG/ | 47,794 | 1,141,000 | 0.28% | ||
| 37 | Informed Momentum Co LLC | 46,132 | 1,102,000 | 0.27% | ||
| 38 | State of New Jersey Common Pension Fund D | 45,000 | 1,075,000 | 0.27% | ||
| 39 | RENAISSANCE TECHNOLOGIES LLC | 43,000 | 1,027,000 | 0.25% | ||
| 40 | RUSSELL FRANK CO/ | 39,995 | 955,000 | 0.24% | ||
| 41 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 36,314 | 867,000 | 0.21% | ||
| 42 | PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 29,260 | 699,000 | 0.17% | ||
| 43 | Swiss National Bank | 24,300 | 580,000 | 0.14% | ||
| 44 | TEACHERS ADVISORS, LLC | 24,080 | 575,000 | 0.14% | ||
| 45 | Capital Impact Advisors, LLC | 21,518 | 514,000 | 0.13% | ||
| 46 | TWO SIGMA INVESTMENTS, LP | 20,947 | 500,000 | 0.12% | ||
| 47 | Alyeska Investment Group, L.P. | 18,908 | 452,000 | 0.11% | ||
| 48 | TFS CAPITAL LLC | 15,822 | 378,000 | 0.09% | ||
| 49 | RHUMBLINE ADVISERS | 14,955 | 357,000 | 0.09% | ||
| 50 | GOLDMAN SACHS GROUP INC | 14,604 | 349,000 | 0.09% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
