| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ADAMAS PHARMACEUTICALS INC | 2,601,351 | 45,524,000 | 9.04% | ||
| 2 | CONCERT PHARMACEUTICALS INCORPORATED | 2,200,000 | 37,532,000 | 7.45% | ||
| 3 | SYNERGY PHARMACEUTICALS DEL | 7,223,509 | 33,662,000 | 6.69% | ||
| 4 | VANDA PHARMACEUTICALS INC COM | 2,232,238 | 31,251,000 | 6.21% | ||
| 5 | RIGEL PHARMACEUTICAL INC | 9,105,691 | 30,140,000 | 5.99% | ||
| 6 | ZOGENIX INC | 2,440,959 | 26,484,000 | 5.26% | ||
| 7 | IGNYTA INC COM | 3,071,300 | 26,413,000 | 5.25% | ||
| 8 | THERAPEUTICSMD INC | 3,460,225 | 24,914,000 | 4.95% | ||
| 9 | NEUROCRINE BIOSCIE COM USD0.001 | 560,000 | 24,248,000 | 4.82% | ||
| 10 | SAGE THERAPEUTICS INC | 301,809 | 21,450,000 | 4.26% | ||
| 11 | SAGE THERAPEUTICS INC | 300,000 | 21,321,000 | 4.23% | Put | |
| 12 | FOAMIX PHARMACEUTICALS LTD | 3,681,708 | 18,224,000 | 3.62% | ||
| 13 | DBV TECHNOLOGIES S A | 485,915 | 17,114,000 | 3.40% | ||
| 14 | AVEXIS INC COM | 200,000 | 15,206,000 | 3.02% | ||
| 15 | PTC THERAPEUTICS INC | 1,468,521 | 14,450,000 | 2.87% | ||
| 16 | ALNYLAM PHARMACEUTICALS INC | 250,000 | 12,813,000 | 2.54% | Call | |
| 17 | GLOBAL BLOOD THERAPEUTICS INCORPORATED | 300,000 | 11,055,000 | 2.20% | ||
| 18 | PARATEK PHARMACEUTICALS INC | 539,571 | 10,387,000 | 2.06% | ||
| 19 | ACORDA THERAPEUTICS INC | 432,500 | 9,083,000 | 1.80% | Put | |
| 20 | NEURODERM LTD | 314,724 | 8,356,000 | 1.66% | ||
| 21 | BOVIE MEDICAL CORP COM | 3,055,000 | 8,157,000 | 1.62% | ||
| 22 | ACCELERON PHARMA INC | 300,000 | 7,941,000 | 1.58% | ||
| 23 | AURINIA PHARMACEUTICALS INC | 1,000,000 | 7,340,000 | 1.46% | ||
| 24 | Sunesis Pharmaceuticals, Inc. | 1,537,873 | 6,305,000 | 1.25% | ||
| 25 | FIVE PRIME THERAPEUTICS INC | 155,265 | 5,613,000 | 1.11% | ||
| 26 | BLUEPRINT MEDICINES CORP COM | 122,129 | 4,884,000 | 0.97% | ||
| 27 | MYOVANT SCIENCES LTD | 407,559 | 4,785,000 | 0.95% | ||
| 28 | CONNECTURE INC | 4,127,232 | 4,416,000 | 0.88% | ||
| 29 | JAZZ PHARMACEUTICALS PLC | 25,000 | 3,628,000 | 0.72% | ||
| 30 | AIMMUNE THERAPEUTICS INC COM | 122,455 | 2,661,000 | 0.53% | ||
| 31 | RADIUS HEALTH INCORPORATED COM NEW | 50,000 | 1,933,000 | 0.38% | Put | |
| 32 | ACORDA THERAPEUTICS INC | 80,000 | 1,680,000 | 0.33% | Call | |
| 33 | CASCADIAN THERAPEUTICS INC | 377,900 | 1,565,000 | 0.31% | ||
| 34 | TREVENA INC | 338,292 | 1,242,000 | 0.25% | ||
| 35 | ARADIGM CORP | 637,279 | 988,000 | 0.20% | ||
| 36 | ALNYLAM PHARMACEUTICALS INC | 11,517 | 590,000 | 0.12% | ||
| 37 | STREAMLINE HEALTH SOLUTIONS COM | 151,611 | 155,000 | 0.03% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0000930413-17-002121, filed 2017.05.15).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
