| # | % | |||||
|---|---|---|---|---|---|---|
| 101 | REXAHN PHARMACEUTICALS INC | 9,071,168 | 2,279,000 | 0.12% | ||
| 102 | VERTEX PHARMACEUTICALS INC | 260 | 2,237,000 | 0.12% | Put | |
| 103 | CLOVIS ONCOLOGY INC | 1,626 | 2,231,000 | 0.12% | Call | |
| 104 | ZOGENIX INC | 12,072 | 2,199,000 | 0.11% | Call | |
| 105 | ABBOTT LABS | 555 | 2,182,000 | 0.11% | Call | |
| 106 | NOVAVAX INC | 3,001 | 2,182,000 | 0.11% | Call | |
| 107 | SAGE THERAPEUTICS INC | 68,950 | 2,077,000 | 0.11% | ||
| 108 | AMARIN CORP PLC | 9,411 | 2,033,000 | 0.11% | Call | |
| 109 | ALCOBRA LTD | 4,467 | 2,006,000 | 0.10% | Call | |
| 110 | CELSION CORPORATION COM PAR | 1,519,365 | 1,930,000 | 0.10% | ||
| 111 | NEURALSTEM INC COM | 6,503,800 | 1,893,000 | 0.10% | ||
| 112 | MOMENTA PHARMACEUTICALS INC | 1,736 | 1,875,000 | 0.10% | Call | |
| 113 | FORWARD PHARMA A/S | 102,135 | 1,856,000 | 0.10% | ||
| 114 | BIODELIVERY SCIENCES INTL IN | 785,799 | 1,854,000 | 0.10% | ||
| 115 | CAPSTONE TURBINE CORP | 1,336,901 | 1,845,000 | 0.10% | ||
| 116 | OPHTHOTECH CORP | 361 | 1,842,000 | 0.10% | Call | |
| 117 | HALOZYME THERAPEUTICS INC | 2,101 | 1,813,000 | 0.09% | Call | |
| 118 | OPKO HEALTH INC | 190,554 | 1,780,000 | 0.09% | ||
| 119 | ALLIQUA BIOMEDICAL INC | 1,500,000 | 1,680,000 | 0.09% | ||
| 120 | REDHILL BIOPHARMA LTD | 147,500 | 1,611,000 | 0.08% | ||
| 121 | FOAMIX PHARMACEUTICALS LTD | 253,706 | 1,611,000 | 0.08% | ||
| 122 | ACADIA PHARMACEUTICALS INC | 495 | 1,607,000 | 0.08% | Put | |
| 123 | FIBROGEN INC | 97,274 | 1,596,000 | 0.08% | ||
| 124 | GW PHARMACEUTICALS PLC | 172 | 1,575,000 | 0.08% | Call | |
| 125 | MOMENTA PHARMACEUTICALS INC | 145,600 | 1,572,000 | 0.08% | ||
| 126 | VANDA PHARMACEUTICALS INC | 1,390 | 1,555,000 | 0.08% | Call | |
| 127 | DEPOMED INC | 788 | 1,546,000 | 0.08% | Call | |
| 128 | WAFERGEN BIO-SYSTEMS INC | 1,867,250 | 1,533,000 | 0.08% | ||
| 129 | FLEXION THERAPEUTICS INC | 100,800 | 1,508,000 | 0.08% | ||
| 130 | REGENERON PHARMACEUTICALS | 43 | 1,502,000 | 0.08% | Call | |
| 131 | ADURO BIOTECH INC | 1,322 | 1,495,000 | 0.08% | Call | |
| 132 | ADAMAS PHARMACEUTICALS INC | 97,600 | 1,478,000 | 0.08% | ||
| 133 | SORRENTO THERAPEUTICS INC COM NEW | 253,805 | 1,421,000 | 0.07% | ||
| 134 | LEXICON PHARMACEUTICALS INC | 979 | 1,405,000 | 0.07% | Put | |
| 135 | EXELIXIS INC | 1,783 | 1,393,000 | 0.07% | Call | |
| 136 | OPKO HEALTH INC | 1,491 | 1,393,000 | 0.07% | Call | |
| 137 | PUMA BIOTECHNOLOGY INC | 458 | 1,364,000 | 0.07% | Call | |
| 138 | BIOBLAST PHARMA LTD | 830,253 | 1,328,000 | 0.07% | ||
| 139 | INSMED INC | 1,346 | 1,327,000 | 0.07% | Call | |
| 140 | RICEBRAN TECHNOLOGIES | 785,476 | 1,304,000 | 0.07% | ||
| 141 | SCYNEXIS INC | 572,928 | 1,243,000 | 0.06% | ||
| 142 | EXPRESS INC COM | 16,386 | 1,242,000 | 0.06% | ||
| 143 | PTC THERAPEUTICS INC | 1,740 | 1,221,000 | 0.06% | Call | |
| 144 | IGNYTA INC COM | 225,000 | 1,220,000 | 0.06% | ||
| 145 | AMICUS THERAPEUTICS INC | 2,234 | 1,220,000 | 0.06% | Put | |
| 146 | TearLab Corp. | 1,882,347 | 1,205,000 | 0.06% | ||
| 147 | DERMIRA INC | 412 | 1,205,000 | 0.06% | Call | |
| 148 | COLLEGIUM PHARMACEUTICAL INC COM | 101,410 | 1,202,000 | 0.06% | ||
| 149 | AERIE PHARMACEUTICALS INC | 674 | 1,186,000 | 0.06% | Call | |
| 150 | CHAMPIONS ONCOLOGY INC | 546,728 | 1,175,000 | 0.06% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-16-119067, filed 2016.08.15).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
