| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 7,619,248 | 80,002,000 | 20.77% | ||
| 2 | WELLINGTON MANAGEMENT GROUP LLP | 3,886,803 | 40,812,000 | 10.59% | ||
| 3 | NEA Management Company, LLC | 3,811,691 | 40,023,000 | 10.39% | ||
| 4 | Polaris Venture Management Co. V, L.L.C. | 2,669,280 | 28,027,000 | 7.28% | ||
| 5 | BlackRock Fund Advisors | 1,464,220 | 15,374,000 | 3.99% | ||
| 6 | CITADEL ADVISORS LLC | 1,433,431 | 15,051,000 | 3.91% | ||
| 7 | BALYASNY ASSET MANAGEMENT L.P. | 1,409,240 | 14,797,000 | 3.84% | ||
| 8 | MILLENNIUM MANAGEMENT LLC | 1,236,680 | 12,985,000 | 3.37% | ||
| 9 | VANGUARD GROUP INC | 1,145,527 | 12,027,000 | 3.12% | ||
| 10 | Broadfin Capital, LLC | 1,000,000 | 10,500,000 | 2.73% | ||
| 11 | BlackRock Institutional Trust Company, N.A. | 957,690 | 10,056,000 | 2.61% | ||
| 12 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 800,000 | 8,400,000 | 2.18% | ||
| 13 | JENNISON ASSOCIATES LLC | 702,341 | 7,375,000 | 1.91% | ||
| 14 | Numeric Investors LLC | 697,503 | 7,324,000 | 1.90% | ||
| 15 | CITIGROUP INC | 621,111 | 6,523,000 | 1.69% | ||
| 16 | PUTNAM INVESTMENTS LLC | 603,080 | 6,332,000 | 1.64% | ||
| 17 | DEUTSCHE BANK AG\ | 459,526 | 4,823,000 | 1.25% | ||
| 18 | Granahan Investment Management, LLC | 451,159 | 4,737,000 | 1.23% | ||
| 19 | BAKER BROS. ADVISORS LP | 450,000 | 4,725,000 | 1.23% | ||
| 20 | STATE STREET CORP | 381,758 | 4,007,000 | 1.04% | ||
| 21 | Informed Momentum Co LLC | 350,222 | 3,677,000 | 0.95% | ||
| 22 | NORTHERN TRUST CORP | 346,122 | 3,635,000 | 0.94% | ||
| 23 | BOGLE INVESTMENT MANAGEMENT L P /DE/ | 316,927 | 3,327,000 | 0.86% | ||
| 24 | RENAISSANCE TECHNOLOGIES LLC | 286,800 | 3,011,000 | 0.78% | ||
| 25 | GEODE CAPITAL MANAGEMENT, LLC | 253,557 | 2,662,000 | 0.69% | ||
| 26 | Connor, Clark & Lunn Investment Management Ltd. | 216,705 | 2,275,000 | 0.59% | ||
| 27 | AWM Investment Company, Inc. | 200,000 | 2,100,000 | 0.55% | ||
| 28 | Bank of New York Mellon Corp | 188,446 | 1,979,000 | 0.51% | ||
| 29 | MARSHALL WACE, LLP | 183,712 | 1,929,000 | 0.50% | ||
| 30 | TIAA CREF INVESTMENT MANAGEMENT LLC | 175,609 | 1,844,000 | 0.48% | ||
| 31 | AMERIPRISE FINANCIAL INC | 145,488 | 1,528,000 | 0.40% | ||
| 32 | NORTHPOINTE CAPITAL LLC | 139,278 | 1,442,000 | 0.37% | ||
| 33 | BLACKROCK ADVISORS LLC | 129,316 | 1,358,000 | 0.35% | ||
| 34 | RUSSELL FRANK CO/ | 124,402 | 1,340,000 | 0.35% | ||
| 35 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 125,000 | 1,313,000 | 0.34% | ||
| 36 | BlackRock Investment Management, LLC | 113,813 | 1,195,000 | 0.31% | ||
| 37 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 103,238 | 1,084,000 | 0.28% | ||
| 38 | AQR CAPITAL MANAGEMENT LLC | 88,360 | 928,000 | 0.24% | ||
| 39 | Trexquant Investment LP | 74,711 | 784,000 | 0.20% | ||
| 40 | PRICE T ROWE ASSOCIATES INC /MD/ | 72,407 | 760,000 | 0.20% | ||
| 41 | UNITED SERVICES AUTOMOBILE ASSOCIATION | 69,430 | 729,000 | 0.19% | ||
| 42 | ALPS ADVISORS INC | 66,877 | 702,000 | 0.18% | ||
| 43 | Nationwide Fund Advisors | 62,847 | 660,000 | 0.17% | ||
| 44 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 57,337 | 602,000 | 0.16% | ||
| 45 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 50,234 | 528,000 | 0.14% | ||
| 46 | Swiss National Bank | 46,000 | 483,000 | 0.13% | ||
| 47 | ProShare Advisors LLC | 45,457 | 477,000 | 0.12% | ||
| 48 | TEACHERS ADVISORS, LLC | 45,014 | 473,000 | 0.12% | ||
| 49 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 43,200 | 454,000 | 0.12% | ||
| 50 | CREDIT SUISSE AG/ | 42,618 | 447,000 | 0.12% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
