| # | % | |||||
|---|---|---|---|---|---|---|
| 251 | LEXICON PHARMACEUTICALS INC | 261,595 | 2,810,000 | 0.12% | ||
| 252 | COMMUNITY HEALTH SYS INC NEW | 662 | 2,831,000 | 0.12% | Put | |
| 253 | NOVAVAX INC | 4,018 | 2,841,000 | 0.12% | Call | |
| 254 | CEMPRA INC | 1,082 | 3,012,000 | 0.12% | Put | |
| 255 | NEUROMETRIX INC | 12,212,278 | 3,052,000 | 0.13% | ||
| 256 | ZAFGEN INC | 960 | 3,067,000 | 0.13% | Call | |
| 257 | PTC THERAPEUTICS INC | 1,161 | 3,100,000 | 0.13% | Call | |
| 258 | BENITEC BIOPHARMA LTD | 505,220 | 3,107,000 | 0.13% | ||
| 259 | Mobileye Nv Call Opt 09/17 48.0 | 686 | 3,120,000 | 0.13% | Call | |
| 260 | VERTEX PHARMACEUTICALS INC | 30,000 | 3,124,000 | 0.13% | ||
| 261 | AOXING PHARMACEUTICAL CO INC | 2,134,054 | 3,158,000 | 0.13% | ||
| 262 | ZELTIQ AESTHETICS INC | 1,000 | 3,203,000 | 0.13% | Call | |
| 263 | LION BIOTECHNOLOGIES INC COM | 561,894 | 3,237,000 | 0.13% | ||
| 264 | AMICUS THERAPEUTICS INC | 2,322 | 3,248,000 | 0.13% | Put | |
| 265 | HORIZON PHARMA PLC | 164,658 | 3,264,000 | 0.13% | ||
| 266 | HORIZON PHARMA PLC | 1,658 | 3,286,000 | 0.14% | Put | |
| 267 | DYNAVAX TECHNOLOGIES CORP | 134,954 | 3,312,000 | 0.14% | ||
| 268 | INTEC PHARMA LTD JERUSALEM | 613,910 | 3,438,000 | 0.14% | ||
| 269 | Skyline Corp | 447,944 | 3,454,000 | 0.14% | ||
| 270 | NEVRO CORP | 745 | 3,456,000 | 0.14% | Put | |
| 271 | BLUEBIRD BIO INC | 406 | 3,473,000 | 0.14% | Put | |
| 272 | ENDO INTL PLC | 50,658 | 3,510,000 | 0.14% | ||
| 273 | VERTEX PHARMACEUTICALS INC | 341 | 3,551,000 | 0.15% | Call | |
| 274 | NORTHWEST BIOTHERAPEUTICS | 572,518 | 3,578,000 | 0.15% | ||
| 275 | TRANSENTERIX INC | 1,591,117 | 3,596,000 | 0.15% | ||
| 276 | NOVAVAX INC COM | 527,040 | 3,726,000 | 0.15% | ||
| 277 | NORTHWEST BIOTHERAPEUTICS IN | 6,042 | 3,776,000 | 0.16% | Put | |
| 278 | OPKO HEALTH INC | 4,500 | 3,785,000 | 0.16% | Call | |
| 279 | CIDARA THERAPEUTICS INC | 306,044 | 3,893,000 | 0.16% | ||
| 280 | HERON THERAPEUTICS INC COM | 160,323 | 3,912,000 | 0.16% | ||
| 281 | RADIUS HEALTH INC | 578 | 4,006,000 | 0.17% | Call | |
| 282 | ENDO INTL PLC | 601 | 4,164,000 | 0.17% | Call | |
| 283 | ZS PHARMA INC | 640 | 4,202,000 | 0.17% | Put | |
| 284 | INOVIO PHARMACEUTICALS INC | 737,551 | 4,263,000 | 0.18% | ||
| 285 | NEUROCRINE BIOSCIENCES INC | 1,267 | 4,397,000 | 0.18% | Put | |
| 286 | RAPTOR PHARMACEUTICAL CORP | 7,289 | 4,410,000 | 0.18% | Call | |
| 287 | ARBUTUS BIOPHARMA CORP | 725,007 | 4,415,000 | 0.18% | ||
| 288 | GILEAD SCIENCES INC | 45,140 | 4,432,000 | 0.18% | ||
| 289 | DERMIRA INC COM | 190,000 | 4,435,000 | 0.18% | ||
| 290 | ISIS PHARMACEUTICALS INC | 1,159 | 4,685,000 | 0.19% | Call | |
| 291 | CELLDEX THERAPEUTICS INC NEW | 4,448 | 4,688,000 | 0.19% | Call | |
| 292 | AVALANCHE BIOTECHNOLOGIES IN | 574,260 | 4,732,000 | 0.19% | ||
| 293 | ACADIA PHARMACEUTICALS INC | 1,438 | 4,755,000 | 0.20% | Call | |
| 294 | ACHILLION PHARMACEUTICALS INC | 6,916 | 4,779,000 | 0.20% | Call | |
| 295 | HCA HOLDINGS INC | 624 | 4,827,000 | 0.20% | Call | |
| 296 | Nivalis Therapeutics Inc | 384,734 | 4,990,000 | 0.21% | ||
| 297 | GENOCEA BIOSCIENCES INC | 729,141 | 4,995,000 | 0.21% | ||
| 298 | DEPOMED INC | 2,680 | 5,052,000 | 0.21% | Call | |
| 299 | DYNAVAX TECHNOLOGIES CORP | 2,073 | 5,087,000 | 0.21% | Call | |
| 300 | FLUIDIGM CORP DEL COM | 628,260 | 5,095,000 | 0.21% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-15-065626, filed 2015.11.16).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
