Dark
Light
System
Institutional Investment Manager
DAFNA Capital Management LLC
DAFNA Capital Management LLC (CIK: 0001389933), located at 10990 Wilshire Boulevard, Los Angeles, CA. Institutional holdings reported to the SEC.

Institutional Holdings (2016Q3)
Portfolio Summary: 74 holdings with a total value of $143,580,000.
#
Name
Shares
Value ($)
%
Options
Notes
1 VITAE PHARMACEUTICALS INC 715,988 14,978,000 10.43%
2 CYNAPSUS THERAPEUTICS INC 230,201 9,256,000 6.45%
3 ATRICURE INC 528,946 8,368,000 5.83%
4 NXSTAGE MED INC COM 238,509 5,960,000 4.15%
5 TANDEM DIABETES CARE INC 724,286 5,548,000 3.86%
6 ALDER BIOPHARMACEUTICALS INC 165,313 5,417,000 3.77%
7 GALAPAGOS NV 66,068 4,272,000 2.98%
8 XENON PHARMACEUTICALS INC 514,091 4,164,000 2.90%
9 AERIE PHARMACEUTICALS INC 91,869 3,467,000 2.41%
10 LOXO ONCOLOGY INC COM 130,222 3,409,000 2.37%
11 DERMIRA INC 98,800 3,341,000 2.33%
12 NEUROCRINE BIOSCIE COM USD0.001 64,008 3,241,000 2.26%
13 INSULET CORPORATION 73,484 3,008,000 2.09%
14 TESARO INC 29,500 2,957,000 2.06%
15 ARDELYX INC COM 219,095 2,835,000 1.97%
16 BEIGENE LTD 90,142 2,777,000 1.93%
17 Protagonist Therapeutics, Inc. 123,804 2,616,000 1.82%
18 Foamix Pharmaceuticals Ltd. 278,067 2,575,000 1.79%
19 INSULET CORP 2 06/15/2019 2,250,000 2,481,000 1.73% PRN
20 APPLIED GENETIC TECHNOL CORP 240,298 2,350,000 1.64%
21 INOTEK PHARMACEUTICALS CORP 237,235 2,249,000 1.57%
22 AEGLEA BIOTHERAPEUTICS INC COM 350,392 2,246,000 1.56%
23 CARA THERAPEUTICS INC 267,046 2,230,000 1.55%
24 OPHTHOTECH CORP COM 46,600 2,150,000 1.50%
25 RADIUS HEALTH 36,854 1,993,000 1.39%
26 IMMUNOMEDICS INC 566,796 1,842,000 1.28%
27 BIOSPECIFICS TECHNOLOGIES CORP COM 39,704 1,813,000 1.26%
28 CYTOKINETICS INC 181,737 1,668,000 1.16%
29 DERMA SCIENCES INC COM PAR .01 353,718 1,652,000 1.15%
30 SPECTRANETICS CORP 65,496 1,643,000 1.14%
31 MACROGENICS INC 54,200 1,621,000 1.13%
32 UNIQURE NV 203,907 1,560,000 1.09%
33 PROTALIX BIOTHERAPEUTICS INC 2,500,000 1,525,000 1.06% PRN
34 SYNERGY PHARMACEUTICALS DEL COM NEW 274,563 1,513,000 1.05%
35 ACHILLION PHARMACEUTICALS INC COM 186,500 1,511,000 1.05%
36 BIOTELEMETRY INC COM 80,000 1,486,000 1.03%
37 REGULUS THERAPEUTICS INC 421,500 1,391,000 0.97%
38 RIGEL PHARMACEUTICAL INC 340,000 1,248,000 0.87%
39 WINDTREE THERAPEUTICS INC 480,833 1,231,000 0.86%
40 EIGER BIOPHARMACEUTICALS INC 90,000 1,205,000 0.84%
41 Stereotaxis Inc 1,372,862 1,194,000 0.83%
42 NOVADAQ TECHNOLOGIES INC 101,841 1,178,000 0.82%
43 JOHNSON & JOHNSON 9,400 1,110,000 0.77%
44 ZOGENIX INC 79,538 909,000 0.63%
45 Exactech Inc 31,636 855,000 0.60%
46 SCYNEXIS INC 213,250 825,000 0.57%
47 INOTEK PHARMACEUTICALS CORP 600,000 794,000 0.55% PRN
48 ESSA Pharma 195,496 733,000 0.51%
49 IRONWOOD PHARMACEUTICALS INC 600,000 717,000 0.50% PRN
50 Dicerna Pharmaceuticals 119,300 701,000 0.49%
Page 1 of 2

Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001389933-16-000037, filed 2016.11.14).

From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.