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Institutional Investment Manager
ORBIMED ADVISORS LLC
ORBIMED ADVISORS LLC (CIK: 0001055951) incorporated in Delaware, located at 601 Lexington Avenue, New York, NY. Institutional holdings reported to the SEC.

Institutional Holdings (2016Q1)
Portfolio Summary: 141 holdings with a total value of $9,503,629,000.
#
Name
Shares
Value ($)
%
Options
Notes
101 INTRA CELLULAR THERAPIES INC COM 294,000 8,173,000 0.09%
102 ULTRAGENYX PHARMACEUTICAL INC COM 128,300 8,123,000 0.09%
103 ENANTA PHARMACEUTICALS INC COM 249,400 7,325,000 0.08%
104 Biotie Therapies Corp. 268,672 7,090,000 0.07%
105 ASSEMBLY BIOSCIENCES INC 1,397,100 7,013,000 0.07%
106 Redhill Biopharma Ltd 564,900 6,920,000 0.07%
107 INCYTE CORP 4,250,000 6,727,000 0.07% PRN
108 INCYTE CORP 4,250,000 6,574,000 0.07% PRN
109 SYNERGY PHARMACEUTICALS DEL COM NEW 2,276,648 6,284,000 0.07%
110 MACROGENICS INC 317,000 5,944,000 0.06%
111 ADVAXIS INC COM NEW 636,600 5,748,000 0.06%
112 QIAGEN NV 256,800 5,737,000 0.06%
113 FLUIDIGM CORP DEL 10,000,000 5,553,000 0.06% PRN
114 Lion Biotechnologies 1,022,100 5,192,000 0.05%
115 MARINUS PHARMACEUTICALS INC 965,000 5,192,000 0.05%
116 VALEANT PHARMACEUTICALS INTL 194,900 5,126,000 0.05%
117 INVITAE CORP 456,666 4,672,000 0.05%
118 CONNECTURE INC COM 1,740,000 4,454,000 0.05%
119 SERES THERAPEUTICS INC 166,645 4,426,000 0.05%
120 MIRATI THERAPEUTICS INC COM 197,859 4,234,000 0.04%
121 Ascendis Pharma 222,223 4,122,000 0.04%
122 ADAPTIMMUNE THERAPEUTICS PLC 438,784 3,567,000 0.04%
123 CERUS CORP 578,300 3,429,000 0.04%
124 MYLAN N V 69,800 3,235,000 0.03%
125 Anacor Pharmaceuticals Inc 53,300 2,849,000 0.03%
126 ALIMERA SCIENCES INC 1,500,000 2,625,000 0.03%
127 ROKA BIOSCIENCE INC 3,220,429 2,222,000 0.02%
128 UNIQURE NV 184,800 2,195,000 0.02%
129 OREXIGEN THERAPEUTICS INC 5,210,000 2,149,000 0.02% PRN
130 PORTOLA PHARMACEUTICALS INC 100,000 2,040,000 0.02% Put
131 MEDIGUS LTD 600,000 1,608,000 0.02%
132 ACHILLION PHARMACEUTICALS INC COM 200,000 1,544,000 0.02% Call
133 XTANT MED HLDGS INC 475,439 1,288,000 0.01%
134 FATE THERAPEUTICS INC COM 692,900 1,247,000 0.01%
135 PERNIX THERAPEUTICS HLDGS IN 1,073,000 1,127,000 0.01%
136 Cogentix Medical Inc 990,745 1,090,000 0.01%
137 BIOLINERX LTD 1,038,600 1,059,000 0.01%
138 QLT INC 500,000 995,000 0.01%
139 BioMarin Pharmaceutical Inc 500,000 594,000 0.01% PRN
140 BIOMARIN PHARMACEUTICAL INC 500,000 579,000 0.01% PRN
141 AMARIN CORP PLC 350,000 536,000 0.01%
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Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001172661-16-003439, filed 2016.05.16).

From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.